Development Level
Tbio | 9,614 | 11,445 | |
Tdark | 3,514 | 6,588 | |
Tchem | 1,427 | 1,598 | |
Tclin | 562 | 613 |
Collection
RFA-RM-18-021 | 277 | 328 | |
Kinase: IDG Consortium (Target... | 107 | 125 | |
GPCR: IDG Consortium (Targets) | 94 | 126 | |
Ion Channel: IDG Consortium (T... | 91 | 99 | |
Kinase: IDG Consortium (Comple... | 32 | 37 | |
GPCR: IDG Consortium (Complete... | 23 | 25 |
IMPC Phenotype
preweaning lethality, complete... | 913 | 979 | |
preweaning lethality, incomple... | 448 | 499 | |
abnormal behavior | 266 | 298 | |
embryonic lethality prior to t... | 257 | 278 | |
embryonic lethality prior to o... | 223 | 239 | |
abnormal embryo size | 201 | 220 | |
enlarged heart | 193 | 210 | |
decreased total body fat amoun... | 188 | 207 | |
decreased vertical activity | 178 | 208 | |
abnormal bone structure | 162 | 187 | |
increased lean body mass | 155 | 172 | |
decreased body weight | 151 | 161 | |
abnormal heart morphology | 150 | 162 | |
decreased bone mineral content | 134 | 151 | |
hyperactivity | 131 | 148 | |
hypoactivity | 121 | 132 | |
decreased lean body mass | 120 | 135 | |
increased total body fat amoun... | 119 | 134 | |
decreased bone mineral density | 116 | 126 | |
decreased circulating glucose ... | 116 | 126 | |
increased circulating alkaline... | 110 | 122 | |
male infertility | 109 | 123 | |
abnormal seminal vesicle morph... | 108 | 114 | |
decreased grip strength | 104 | 116 | |
embryonic growth retardation | 99 | 106 | |
increased startle reflex | 99 | 112 | |
increased bone mineral content | 97 | 108 | |
decreased body length | 89 | 101 | |
increased mean corpuscular hem... | 89 | 96 | |
increased or absent threshold ... | 88 | 101 | |
short tibia | 86 | 97 | |
increased mean corpuscular vol... | 85 | 92 | |
cataract | 83 | 92 | |
decreased circulating choleste... | 83 | 93 | |
prenatal lethality prior to he... | 81 | 87 | |
decreased lymphocyte cell numb... | 77 | 83 | |
decreased prepulse inhibition | 77 | 82 | |
increased circulating HDL chol... | 76 | 80 | |
decreased circulating triglyce... | 72 | 79 | |
decreased circulating serum al... | 71 | 82 | |
improved glucose tolerance | 71 | 79 | |
abnormal lens morphology | 70 | 81 | |
decreased mean corpuscular vol... | 70 | 79 | |
decreased startle reflex | 69 | 75 | |
increased fasted circulating g... | 69 | 76 | |
increased circulating sodium l... | 68 | 71 | |
decreased circulating insulin ... | 67 | 76 | |
impaired glucose tolerance | 67 | 75 | |
small superior vagus ganglion | 67 | 74 | |
abnormal retina morphology | 65 | 71 | |
abnormal eye morphology | 64 | 68 | |
abnormal gait | 63 | 69 | |
abnormal sleep behavior | 63 | 70 | |
decreased leukocyte cell numbe... | 63 | 73 | |
decreased hemoglobin content | 62 | 68 | |
increased circulating choleste... | 62 | 66 | |
decreased fasted circulating g... | 60 | 65 | |
increased bone mineral density | 60 | 72 | |
abnormal behavioral response t... | 59 | 66 | |
decreased circulating HDL chol... | 59 | 68 | |
decreased erythrocyte cell num... | 59 | 62 | |
increased monocyte cell number | 59 | 63 | |
abnormal kidney morphology | 58 | 65 | |
increased heart weight | 56 | 62 | |
abnormal coat-hair pigmentatio... | 55 | 64 | |
edema | 55 | 59 | |
small testis | 55 | 58 | |
thrombocytopenia | 55 | 56 | |
female infertility | 54 | 60 | |
abnormal spleen morphology | 52 | 55 | |
hydrometra | 50 | 53 | |
decreased caudal vertebrae num... | 49 | 53 | |
decreased circulating total pr... | 47 | 49 | |
decreased blood urea nitrogen ... | 46 | 51 | |
decreased mean corpuscular hem... | 46 | 50 | |
decreased circulating alanine ... | 44 | 47 | |
abnormal skin morphology | 43 | 50 | |
decreased circulating alkaline... | 43 | 46 | |
increased leukocyte cell numbe... | 43 | 47 | |
increased neutrophil cell numb... | 43 | 46 | |
abnormal neural tube closure | 42 | 46 | |
abnormal testis morphology | 42 | 43 | |
decreased hematocrit | 42 | 46 | |
increased mean platelet volume | 42 | 45 | |
increased blood urea nitrogen ... | 41 | 48 | |
abnormal epididymis morphology | 39 | 42 | |
decreased neutrophil cell numb... | 39 | 42 | |
decreased red blood cell distr... | 39 | 41 | |
increased grip strength | 39 | 41 | |
increased circulating triglyce... | 38 | 42 | |
increased hematocrit | 38 | 46 | |
limb grasping | 38 | 41 | |
increased hemoglobin content | 37 | 45 | |
prolonged QT interval | 37 | 38 | |
decreased circulating LDL chol... | 36 | 38 | |
decreased circulating calcium ... | 36 | 36 | |
decreased circulating creatini... | 36 | 39 | |
enlarged spleen | 36 | 41 | |
increased circulating chloride... | 36 | 41 | |
prolonged ST segment | 36 | 36 |
Disease
Tissue
Endocrine System | 14,648 | 18,159 | |
Digestive Tract | 14,209 | 17,369 | |
Female tissues | 14,193 | 17,400 | |
Skin and soft tissues | 14,108 | 17,230 | |
Male tissues | 14,036 | 17,142 | |
Blood and immune system | 13,864 | 16,909 | |
Nervous System | 13,818 | 16,725 | |
Liver and Pancreas | 13,794 | 16,750 | |
Urinary Tract | 13,766 | 16,678 | |
Respiratory system | 13,506 | 16,393 | |
Cardiovascular System | 12,675 | 15,192 |
Target Family
Non-IDG | 8,607 | 12,091 | |
Enzyme | 3,452 | 4,145 | |
Transcription Factor | 943 | 1,400 | |
Kinase | 561 | 634 | |
Transporter | 419 | 473 | |
GPCR | 339 | 408 | |
Ion Channel | 315 | 344 | |
oGPCR | 210 | 421 | |
Epigenetic | 198 | 242 | |
Nuclear Receptor | 43 | 48 | |
TF/Epigenetic | 30 | 38 |
Ortholog Species
Rat | 15,117 | 15,117 | |
Mouse | 16,570 | 16,570 | |
Cow | 15,320 | 15,320 | |
Dog | 15,073 | 15,073 | |
Horse | 14,252 | 14,252 | |
Chimp | 14,140 | 14,140 | |
Macaque | 12,761 | 12,761 | |
Opossum | 12,230 | 12,230 | |
Anole lizard | 10,588 | 10,588 | |
Xenopus | 10,468 | 10,468 | |
Pig | 10,168 | 10,168 | |
Zebrafish | 9,726 | 9,726 | |
Chicken | 7,827 | 7,827 | |
Platypus | 5,703 | 5,703 | |
C. elegans | 3,179 | 3,179 | |
Fruitfly | 3,050 | 3,050 | |
S.cerevisiae | 1,799 | 1,799 |
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