Development Level

Tclin 1 | 612

IMPC Phenotype

decreased hemoglobin content 1 | 68
tremors 1 | 39

Disease

Abdomen distended 1 | 43
Adenocarcinoma, Follicular 1 | 2
Attention deficit hyperactivity disorder 1 | 278
Autosomal recessive predisposition 1 | 1,442
Becker muscular dystrophy 1 | 191
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Coarse facial features 1 | 108
Congenital deafness 1 | 185
Congenital hypothyroidism 1 | 26
Congenital pectus carinatum 1 | 52
Constipation 1 | 181
Convex nasal ridge 1 | 37
Craniofacial Abnormalities 1 | 151
Deafness 1 | 198
Delayed bone age 1 | 136
Delayed speech and language development 1 | 112
Diagnostic Test for Thyroid Dysfunction 1 | 3
Diaphragmatic Hernia 1 | 40
Dyschezia 1 | 135
Enhanced S-cone syndrome 1 | 17
Exophthalmos 1 | 112
Feeding difficulties 1 | 127
Follicular thyroid carcinoma 1 | 14
Generalized resistance to thyroid hormone 1 | 1
Goiter 1 | 38
Graves' disease 1 | 24
Hashimoto Thyroiditis 1 | 3
Hearing Loss, Partial 1 | 185
Hernia, Diaphragmatic 1 | 40
Hyperlipidemia 1 | 43
Hyperthyroidism 1 | 53
Hyperthyroxinemia 1 | 9
Hypothyroidism 1 | 122
Icterus 1 | 82
Increased serum free triiodothyronine 1 | 1
Language Delay 1 | 112
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Low Birth Weights 1 | 69
Macroglossia 1 | 65
Malignant tumor of thyroid gland 1 | 3
Mild Hypothyroidism 1 | 2
Muscle hypotonia 1 | 571
Myxedema 1 | 11
Myxedema coma 1 | 2
Peripheral resistance to thyroid hormones 1 | 2
Peripheral vascular disease 1 | 87
Pituitary adenoma 1 | 38
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Radial neuropathy 1 | 3
Raised TSH level 1 | 8
Sensorineural Hearing Loss (disorder) 1 | 284
Sickle Cell Anemia 1 | 53
Simple goiter 1 | 2
Sleep disturbances 1 | 37
Small for gestational age (disorder) 1 | 69
Speech Delay 1 | 112
Speech impairment 1 | 112
Sprengel deformity 1 | 16
Stippled epiphyses 1 | 28
T3 Suppression for Thyroid Function Test 1 | 2
THYROID HORMONE RESISTANCE, GENERALIZED, AUTOSOMAL DOMINANT 1 | 1
THYROID HORMONE RESISTANCE, SELECTIVE PITUITARY 1 | 1
Thickened facial skin with coarse facial features 1 | 108
Thyroid Diseases 1 | 24
Thyroid Hormone Resistance Syndrome 1 | 5
Thyroid Hormone Resistance, Generalized, Autosomal Recessive 1 | 1
Thyrotoxicosis 1 | 38
Umbilical hernia 1 | 93
Wide bregma sutures 1 | 46
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
head and neck cancer 1 | 271
hearing impairment 1 | 199
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma, large-cell 1 | 6,241
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Nuclear Receptor 1 | 48

OMIM Phenotype

Thyroid hormone resistance, au... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid hormone receptor beta THRB Tclin Nuclear Receptor -2.82486 627.3 399