Development Level

Tchem 2 | 1,598

IMPC Phenotype

increased circulating glucose ... 1 | 24
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Abnormal dermatoglyphic pattern 2 | 24
Abnormality of cranial vault shape 2 | 5
Abnormality of cranium shape 2 | 5
Abnormality of dental color 2 | 5
Abnormality of head shape 2 | 5
Abnormality of vision 2 | 40
Alopecia 2 | 115
Asymmetric growth 2 | 5
Asymmetry of head 2 | 5
Asymmetry of the posterior cranium 2 | 20
Basal cell carcinoma 2 | 54
Basal cell nevi 2 | 23
Blepharoptosis 2 | 231
Byzanthine arch palate 2 | 194
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cerebellar hypoplasia and atrophy 2 | 41
Conduction disorder of the heart 2 | 79
Congenital ocular coloboma (disorder) 2 | 40
Congenital pectus carinatum 2 | 52
Connective tissue cancer 2 | 10
Cranial asymmetry 2 | 5
Curly hair (finding) 2 | 14
DOID:2415 2 | 5
Decreased to absent deep tendon reflexes 2 | 42
Defect of vertebral segmentation 2 | 17
Delayed bone age 2 | 136
Dental abnormalities 2 | 60
Downward slant of palpebral fissure 2 | 158
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Electroencephalogram abnormal 2 | 101
Epidermal Nevus 2 | 4
Epidermal nevus syndrome 2 | 3
Excess nuchal skin 2 | 30
Facial asymmetry 2 | 32
Fetal overgrowth 2 | 16
Fibrous skin tumor of tuberous sclerosis 2 | 18
Finger abnormalities 2 | 3
Flattening of cranial vault 2 | 20
Flattening of head 2 | 20
Frequent fractures 2 | 53
Frontal bossing 2 | 157
Full lower lip 2 | 64
Generalized osteopenia 2 | 99
Generalized overgrowth 2 | 16
Genu recurvatum 2 | 12
Hemangioma 2 | 69
Hemangioma, Cavernous 2 | 20
Hemimegalencephaly 2 | 5
Horseshoe Kidney 2 | 16
Hyperkeratosis 2 | 50
Hyperreflexia 2 | 209
Hypophosphatemic Rickets 2 | 11
Hypopigmentation disorder 2 | 25
Ichthyoses 2 | 41
Increased fracture rate 2 | 53
Irregular hyperpigmentation 2 | 33
Isolated cases 2 | 72
Joint hyperflexibility 2 | 78
Kyphoscoliosis deformity of spine 2 | 60
Malformation of cranial vault shape 2 | 5
Malformation of cranium shape 2 | 5
Malformation of head shape 2 | 5
Melanocytic Nevus Syndrome, Congenital 2 | 3
Melanocytic nevus 2 | 43
Melanoma 2 | 711
Neoplasms, Experimental 2 | 40
Neuroblastoma 2 | 80
Nevus sebaceous 2 | 3
Nevus, Epidermal 2 | 5
Nevus, Sebaceous of Jadassohn 2 | 3
Noncancerous mole 2 | 28
Noonan syndrome 2 | 34
Osteopenia 2 | 99
Overgrowth 2 | 16
Papillary thyroid carcinoma 2 | 43
Plagiocephaly 2 | 20
Plagiocephaly, Nonsynostotic 2 | 20
Plummer's disease 2 | 11
Porencephaly 2 | 20
Prominent back of the head 2 | 21
Prominent lower lip 2 | 64
Prominent occiput 2 | 21
Rhabdomyosarcoma 2 | 39
Rhomboid shaped head 2 | 20
Sebaceous adenoma 2 | 26
Seizures 2 | 596
Somatic mosaicism 2 | 6
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
Telecanthus 2 | 62
Thyroid Cancer, Nonmedullary, 2 2 | 6
Thyroid cancer 2 | 36
Thyroid cancer, follicular 2 | 8
Toe abnormalities 2 | 4
Tooth Abnormalities 2 | 69
Upper respiratory tract disease 2 | 15
Varying degree of multiple fractures 2 | 53

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

OMIM Phenotype

Thyroid carcinoma, follicular,... 2 | 2
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328