Development Level

Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Alopecia areata 1 | 41
Atony of facial musculature 1 | 3
Autistic Disorder 1 | 364
Babinski Reflex 1 | 100
Big calvaria 1 | 147
Brachydactyly 1 | 156
Carcinoma 1 | 11,493
Carcinoma, Renal Cell 1 | 124
Class III malocclusion 1 | 78
Congenital clubfoot 1 | 109
Congenital hypoplasia of penis 1 | 176
Cryptorchidism 1 | 296
Decreased projection of maxilla 1 | 66
Deficiency of upper jaw bones 1 | 66
Delayed speech and language development 1 | 112
Diastema of Teeth 1 | 4
Enophthalmos 1 | 75
Epilepsy 1 | 792
Facial hypotonia 1 | 3
Fissured tongue 1 | 25
Gait, Shuffling 1 | 8
High, narrow palate 1 | 32
Hyperopia 1 | 70
Hyperreflexia 1 | 209
Hypertrophy of lower jaw 1 | 78
Hypoplasia of forehead 1 | 2
Hypoplasia of the maxilla 1 | 66
Hypoplastic feet 1 | 66
Hypoplastic mandible condyle 1 | 275
Hypotrophic forehead 1 | 2
Hypotrophic maxilla 1 | 66
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of mandible 1 | 78
Increased size of skull 1 | 147
Intellectual disability 1 | 1,016
Jensen syndrome 1 | 6
Kidney cancer 1 | 2,613
Language Delay 1 | 112
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large hand 1 | 18
Large intestine cancer 1 | 126
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Low frustration tolerance 1 | 2
Lower limb atrophy 1 | 8
Lower limb hyperreflexia 1 | 10
Lower limb hypertonia 1 | 2
Lower limb muscle hypotrophy 1 | 8
MENTAL RETARDATION, X-LINKED, SYNDROMIC, CLAES-JENSEN TYPE 1 | 1
Macrotia 1 | 87
Mandibular hyperplasia 1 | 78
Mandibular hypoplasia 1 | 275
Maxillary retrognathia 1 | 66
Mental Retardation, X-Linked, Syndromic, Jarid1c-Related 1 | 1
Micrognathism 1 | 275
Muscle Spasticity 1 | 195
Muscle atrophy, lower limb, distal 1 | 8
Myopia 1 | 176
Pectus excavatum 1 | 100
Physical aggression 1 | 76
Progressive mental retardation 1 | 37
Progressive spastic paraplegia 1 | 2
Renal Cell Carcinoma 1 | 214
Restlessness 1 | 14
Retrusion of upper jaw bones 1 | 66
Seizures 1 | 596
Severe mental retardation (I.Q. 20-34) 1 | 99
Short distal phalanges 1 | 50
Short stature 1 | 531
Small forehead 1 | 2
Smooth philtrum 1 | 43
Speech Delay 1 | 112
Speech impairment 1 | 112
Sunken eyes 1 | 63
Talipes Calcaneovarus 1 | 2
Thin upper lip vermilion 1 | 67
Upward slant of palpebral fissure 1 | 75
X- linked recessive 1 | 110
lung cancer 1 | 4,740
mandibular excess (physical finding) 1 | 78
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
psoriasis 1 | 6,694

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

TF/Epigenetic 1 | 38

OMIM Phenotype

Phenotype: Mental retardation,... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysine-specific demethylase 5C KDM5C Tchem TF/Epigenetic -1.94004 86.4 135