Development Level

Tbio 4 | 11,651

IMPC Phenotype

abnormal heart morphology 1 | 162
enlarged heart 1 | 210
increased circulating alkaline... 1 | 122
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46

Disease

Myocardial Infarction 4 | 151
psoriasis 4 | 6,694
Schizophrenia 3 | 1,160
colon cancer 3 | 1,478
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
Cancer 2 | 2,499
Coronary artery disease 2 | 268
Major Depressive Disorder 2 | 301
Unipolar Depression 2 | 250
adult high grade glioma 2 | 3,801
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
Alcoholic Intoxication, Chronic 1 | 289
Alzheimer's disease 1 | 658
Ancylostomiasis 1 | 6
Antiphospholipid syndrome 1 | 19
Arthritis, Juvenile 1 | 126
Arthritis, Psoriatic 1 | 14
Asthma 1 | 385
Astrocytoma, Pilocytic 1 | 3,081
Atherosclerosis 1 | 291
Atopic dermatitis 1 | 952
Berylliosis 1 | 28
Breast cancer 1 | 3,578
Carcinoma 1 | 11,493
Cardiomyopathies 1 | 110
DOID:3394 1 | 1
Heart failure 1 | 162
Hepatic encephalopathy 1 | 27
Hypersensitivity reaction type II disease 1 | 253
Hypertension 1 | 396
Hypertensive disease 1 | 292
Juvenile arthritis 1 | 126
Leprosy 1 | 73
Lipid metabolism disorder 1 | 114
Lissencephaly 1 | 69
Mesothelioma, Malignant 1 | 105
Multiple Sclerosis 1 | 540
Nerve Degeneration 1 | 121
Pick disease 1 | 1,894
Psychoses, Drug 1 | 9
Residual schizophrenia 1 | 2
Rheumatoid arthritis 1 | 1,191
Sepsis 1 | 24
Shared Paranoid Disorder 1 | 5
Syndromic X-linked intellectual disability Snyder type 1 | 21
Toxic encephalopathy 1 | 141
Toxic shock syndrome 1 | 28
Type 1 diabetes mellitus 1 | 109
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
atypical teratoid / rhabdoid tumor 1 | 5,112
breast carcinoma 1 | 1,638
cutaneous lupus erythematosus 1 | 1,057
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
gastric cancer 1 | 459
group 4 medulloblastoma 1 | 1,855
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung carcinoma 1 | 2,843
mucosa-associated lymphoid tissue lymphoma 1 | 484
nasopharyngeal carcinoma 1 | 1,058
osteoporosis-pseudoglioma syndrome 1 | 9
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
primary Sjogren syndrome 1 | 735
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Respiratory system 4 | 16,393
Urinary Tract 4 | 16,678
Cardiovascular System 3 | 15,192
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Skin and soft tissues 3 | 17,230

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145

OMIM Phenotype

Phenotype: {Myocardial infarct... 4 | 4
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate--cysteine ligase regulatory subunit GCLM Tbio Enzyme -2.23855 156.3 277
Lymphotoxin-alpha LTA Tbio Non-IDG -2.87108 629.6 561
Low-density lipoprotein receptor-related protein 8 LRP8 Tbio Non-IDG -2.17223 148.7 283
Oxidized low-density lipoprotein receptor 1 OLR1 Tbio Non-IDG -2.81842 744.2 439