Development Level

Tbio 2 | 11,445

IMPC Phenotype

abnormal retina morphology 1 | 71
decreased caudal vertebrae num... 1 | 53
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased lean body mass 1 | 172
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Bipolar Disorder 2 | 666
Carcinoma 2 | 11,493
Duchenne muscular dystrophy 2 | 601
Neurodevelopmental Disorders 2 | 70
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abnormal coordination 1 | 15
Absent speech 1 | 43
Acquired metabolic disease 1 | 336
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Amyotrophic lateral sclerosis 1 | 451
Arthritis, Juvenile 1 | 126
Astigmatism 1 | 54
Atopic dermatitis 1 | 952
Autonomic nervous system disorders 1 | 19
Broad flat nasal bridge 1 | 236
Cancer 1 | 2,499
Capuchin ears 1 | 17
Cardiovascular system disease 1 | 246
Clubbing 1 | 9
Coarse facial features 1 | 108
Colonic Neoplasms 1 | 142
Colorectal Neoplasms 1 | 243
Constipation 1 | 181
Corneal disease 1 | 31
Coronary Disease 1 | 25
Craniofacial Abnormalities 1 | 151
Cupped ears (finding) 1 | 17
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Dysautonomia 1 | 20
Dyschezia 1 | 135
Encephalopathies 1 | 43
Enophthalmos 1 | 75
Epilepsy 1 | 792
Gait Ataxia 1 | 51
Gastroesophageal reflux disease 1 | 110
Heartburn 1 | 78
Hyperplasia 1 | 27
Hypoplasia of corpus callosum 1 | 90
Juvenile arthritis 1 | 126
Liver Cirrhosis, Experimental 1 | 769
Liver neoplasms 1 | 130
Melanoma 1 | 711
Metabolic syndrome X 1 | 52
Microcephaly 1 | 166
Motor delay 1 | 147
Myopia 1 | 176
Narrow forehead 1 | 34
Nasal bridge wide 1 | 236
No development of motor milestones 1 | 147
Parkinson's disease 1 | 392
Peripheral Neuropathy 1 | 134
Physical aggression 1 | 76
Polycystic ovary syndrome 1 | 360
Psychotic Disorders 1 | 151
Schizoaffective Disorder 1 | 55
Seizures 1 | 596
Severe mental retardation (I.Q. 20-34) 1 | 99
Short philtrum 1 | 53
Skin cancer 1 | 469
Strabismus 1 | 270
Sunken eyes 1 | 63
Tapering fingers (finding) 1 | 25
Thickened facial skin with coarse facial features 1 | 108
Type 2 diabetes mellitus 1 | 272
Upward slant of palpebral fissure 1 | 75
acute quadriplegic myopathy 1 | 1,158
aldosterone-producing adenoma 1 | 665
esophageal adenocarcinoma 1 | 737
head and neck cancer 1 | 271
lung adenocarcinoma 1 | 2,716
nephrosclerosis 1 | 333
nonverbal 1 | 43
pancreatic carcinoma 1 | 562
pituitary cancer 1 | 1,972
pterygium 1 | 76

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Transcription Factor 2 | 1,400

OMIM Phenotype

Phenotype: {Diabetes mellitus,... 2 | 2
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor 4 TCF4 Tbio Transcription Factor -2.57908 320.1 249
Transcription factor 7-like 2 TCF7L2 Tbio Transcription Factor -2.63620 474.2 327