Development Level

Tchem 2 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Carcinoma 2 | 11,493
Major Depressive Disorder 2 | 301
Psychotic Disorders 2 | 151
Schizophrenia 2 | 1,160
Unipolar Depression 2 | 250
ATTENTION DEFICIT-HYPERACTIVITY DISORDER, SUSCEPTIBILITY TO, 7 1 | 1
Alcohol abuse 1 | 50
Alcohol dependence 1 | 107
Amyotrophic lateral sclerosis 1 | 451
Anxiety disorder 1 | 23
Attention Deficit Disorder with Hyperactivity 1 | 21
Attention deficit hyperactivity disorder 1 | 278
Breast cancer 1 | 3,578
Cocaine Dependence 1 | 51
Depression, Bipolar 1 | 12
Depressive Disorder, Major 1 | 19
Depressive disorder 1 | 409
Drug-induced depressive state 1 | 14
Fever 1 | 138
Gilles de la Tourette syndrome 1 | 47
Kidney cancer 1 | 2,613
Mental Depression 1 | 333
Mood Disorders 1 | 184
Nonorganic psychosis 1 | 84
Oppositional defiant disorder 1 | 17
Paranoid Schizophrenia 1 | 18
Pellagra 1 | 26
Photosensitivity disease 1 | 1
Porphyria 1 | 10
SCHIZOPHRENIA 1 (disorder) 1 | 1
Starvation 1 | 1
Substance Use Disorders 1 | 1
Substance abuse 1 | 59
Sudden infant death syndrome 1 | 32
alcohol use disorder 1 | 12
astrocytic glioma 1 | 2,597
breast carcinoma 1 | 1,638
cutaneous lupus erythematosus 1 | 1,057
ductal carcinoma in situ 1 | 1,745
gastric carcinoma 1 | 807
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
malignant mesothelioma 1 | 3,232
medulloblastoma 1 | 720
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
ovarian cancer 1 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
periodontitis 1 | 293
pituitary cancer 1 | 1,972
primary Sjogren syndrome 1 | 735
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
spina bifida 1 | 1,074
ulcerative colitis 1 | 1,819

Tissue

Endocrine System 2 | 18,159
Nervous System 2 | 16,725
Blood and immune system 1 | 16,909
Digestive Tract 1 | 17,369
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Enzyme 2 | 4,145

OMIM Phenotype

Phenotype: [?Hypertryptophanem... 2 | 2
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tryptophan 5-hydroxylase 2 TPH2 Tchem Enzyme -2.44646 308.6 361
Tryptophan 2,3-dioxygenase TDO2 Tchem Enzyme -2.89113 773.6 193