Development Level

Tclin 1 | 613

IMPC Phenotype

decreased circulating alkaline... 1 | 46
preweaning lethality, complete... 1 | 979

Disease

Acetazolamide responsive myotonia 1 | 1
Acetazolamide-responsive myotonia 1 | 1
Administration of Local Anesthetic Nerve Block 1 | 14
Administration of Regional Anesthesia 1 | 7
Anesthesia for cesarean section 1 | 8
Apneic episodes in infancy 1 | 2
Bipolar disorder in remission 1 | 19
Chest Pain 1 | 38
Congenital myasthenic syndrome, acetazolamide-responsive 1 | 5
Cough 1 | 23
Deglutition Disorders 1 | 132
Dysuria 1 | 26
Epilepsy characterized by intractable complex partial seizures 1 | 28
Episodic flaccid weakness 1 | 4
Episodic hypokalemia 1 | 4
Exercise-induced muscle fatigue 1 | 5
External Ophthalmoplegia 1 | 6
Glossopharyngeal neuralgia 1 | 5
HYPOKALEMIC PERIODIC PARALYSIS, TYPE 1 1 | 2
Handgrip myotonia 1 | 3
Hemorrhoids 1 | 13
Hyperglycemia, Postprandial 1 | 8
Hyperkalemia 1 | 17
Hyperkalemic periodic paralysis 1 | 9
Hypokalemia 1 | 52
Hypokalemic Periodic Paralysis, Type 2 1 | 1
Hypokalemic periodic paralysis 1 | 11
Hypokalemic periodic paralysis 1 1 | 2
Hypokalemic periodic paralysis type 1 1 | 3
Increased intramyocellular lipid droplets 1 | 13
Infestation by Phthirus pubis 1 | 7
Infestation by Sarcoptes scabiei var hominis 1 | 7
Inspiratory stridor 1 | 2
Itching of skin 1 | 18
Lennox-Gastaut syndrome 1 | 34
Life-Threatening Ventricular Tachycardia 1 | 15
Local Anesthesia for Endotracheal Intubation 1 | 6
Local Anesthesia for Ophthalmologic Procedure 1 | 7
Local Anesthesia for Urethral Pain 1 | 6
Local anesthesia 1 | 40
Local anesthesia, by infiltration 1 | 14
Local anesthetic intrathecal block 1 | 7
Localization-related epilepsy 1 | 13
MYASTHENIC SYNDROME, CONGENITAL, 16 1 | 1
Major Nerve Block for Surgery 1 | 8
Malignant hyperthermia 1 | 26
Mildly increased creatine kinase 1 | 20
Minor Skin Wound Pain 1 | 12
Mixed Epilepsy 1 | 3
Motor cortex epilepsy 1 | 10
Mouth Irritation 1 | 12
Muscle Cramp 1 | 55
Muscle Weakness 1 | 170
Muscular fasciculation 1 | 22
Muscular stiffness 1 | 12
Myalgia 1 | 54
Myasthenias 1 | 8
Myasthenic Syndromes, Congenital 1 | 16
Myotonia 1 | 10
Myotonia Fluctuans (disorder) 1 | 1
Myotonia congenita 1 | 8
Myotonia fluctuans 1 | 1
Myotonia permanens 1 | 1
Myotonic Disorders 1 | 2
Noisy respiration 1 | 5
Paradoxical myotonia 1 | 1
Paralysis, Hyperkalemic Periodic 1 | 1
Paramyotonia Congenita (disorder) 1 | 1
Paramyotonia congenita of von Eulenburg 1 | 1
Pediculosis capitis 1 | 7
Percussion Myotonia 1 | 1
Periodic hypokalemic paresis 1 | 7
Postherpetic neuralgia 1 | 11
Potassium aggravated myotonia 1 | 1
Potassium-aggravated myotonia 1 | 1
Prevent Minor Bacterial Skin Infection 1 | 10
Prevention of Seizures following Cranial Trauma or Surgery 1 | 7
Pruritus ani 1 | 14
Regional Anesthesia for Labor Pain 1 | 9
Regional Anesthesia for Ophthalmologic Surgery 1 | 6
Regional Anesthesia for Postoperative Pain 1 | 9
Regional Anesthesia for Surgery 1 | 9
Seizures in Neurosurgery 1 | 7
Simple partial seizure 1 | 26
Skeletal muscle hypertrophy 1 | 16
Sore throat symptom 1 | 12
Spasticity 1 | 26
Stridor 1 | 5
Suppression of the Gag Reflex 1 | 12
Tachyarrhythmia 1 | 2
Thyrotoxicosis 1 | 38
Tinea Infections 1 | 10
Tinea corporis 1 | 25
Tonic-clonic epilepsy 1 | 47
Tonic-clonic seizure 1 | 11
Trigeminal Neuralgia 1 | 24
Urethritis 1 | 10
Urinary Tract Irritation 1 | 24
Ventricular arrhythmia 1 | 27
periodic paralysis (finding) 1 | 3

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Ion Channel 1 | 344

OMIM Phenotype

Myotonia congenita, atypical, ... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 4 subunit alpha SCN4A Tclin Ion Channel -2.57811 366.4 57