Development Level

Tchem 1 | 1,598

Disease

AUDITORY NEUROPATHY, AUTOSOMAL DOMINANT, 1 1 | 2
Abnormality of the iris 1 | 14
Abortion, Spontaneous 1 | 109
Acquired flat foot 1 | 72
Acquired scoliosis 1 | 281
Aneurysm, Dissecting 1 | 8
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm 1 | 38
Aortic aneurysm, familial thoracic 3 1 | 13
Arachnodactyly 1 | 49
Arterial tortuosity 1 | 5
Arterial tortuosity syndrome 1 | 7
Ascending aortic dissection 1 | 13
Astrocytoma, Pilocytic 1 | 3,081
Atypical scarring of skin 1 | 62
Blue sclera 1 | 32
Breast cancer 1 | 3,578
Byzanthine arch palate 1 | 194
Camurati-Engelmann disease 1 | 6
Cancer 1 | 2,499
Carcinoma 1 | 11,493
Cardiomegaly 1 | 116
Chemical and Drug Induced Liver Injury 1 | 195
Chest Pain 1 | 38
Cleft Palate 1 | 271
Cleft palate with cleft lip 1 | 23
Cleft uvula 1 | 27
Colorectal Neoplasms 1 | 243
Coronary artery disease 1 | 268
Craniosynostosis 1 | 74
Curvature of spine 1 | 282
Cutis marmorata 1 | 32
Cystic medial necrosis of aorta 1 | 13
Descending aortic dissection 1 | 13
Dissection of aorta 1 | 9
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Ehlers-Danlos syndrome 1 | 43
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Flatfoot 1 | 73
Flexion contracture of proximal interphalangeal joint 1 | 75
Gaucher disease type 1 1 | 180
Hereditary hemorrhagic telangiectasia 1 | 13
Hypertensive disease 1 | 292
Hypoplastic mandible condyle 1 | 275
Hypotrophic malar bone 1 | 129
Idiopathic pulmonary fibrosis 1 | 23
Impaired left ventricular function 1 | 16
Increase in blood pressure 1 | 119
Keratoacanthoma familial 1 | 1
Kidney cancer 1 | 2,613
Left-Sided Heart Failure 1 | 16
Linear atrophy 1 | 15
Liver Cirrhosis 1 | 181
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Loeys-Dietz Syndrome 1 1 | 1
Loeys-Dietz syndrome 1 | 23
MULTIPLE SELF-HEALING SQUAMOUS EPITHELIOMA, SUSCEPTIBILITY TO 1 | 1
Macular degeneration 1 | 65
Malar flattening 1 | 129
Mandibular hypoplasia 1 | 275
Micrognathism 1 | 275
Multiple self-healing squamous epithelioma 1 | 1
Oral cleft 1 | 18
Orbital separation excessive 1 | 244
Patent ductus arteriosus 1 | 90
Prostate cancer 1 | 175
Pulmonary Fibrosis 1 | 106
Skin Neoplasms 1 | 69
Skull malformation 1 | 38
Spontaneous abortion 1 | 113
Systemic scleroderma 1 | 60
Tall stature 1 | 34
Thoracic aortic aneurysm 1 | 15
Uremia 1 | 19
Ureteral obstruction 1 | 33
Uterine Rupture 1 | 2
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
astrocytoma 1 | 1,146
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
juvenile dermatomyositis 1 | 1,187
medulloblastoma, large-cell 1 | 6,241
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
primitive neuroectodermal tumor 1 | 3,035

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Kinase 1 | 634

OMIM Phenotype

Multiple self-healing squamous... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413