Development Level

Tbio 1 | 11,445

Disease

Acquired scoliosis 1 | 281
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Almond-shaped eyes 1 | 23
Amyotrophic lateral sclerosis 1 | 451
Asthma, Occupational 1 | 10
Asymmetry of the posterior cranium 1 | 20
Attention deficit hyperactivity disorder 1 | 278
Autosomal recessive predisposition 1 | 1,442
Class III malocclusion 1 | 78
Clitoral hypoplasia 1 | 11
Cognitive delay 1 | 608
Colitis, Ulcerative 1 | 59
Curvature of digit 1 | 57
Curvature of spine 1 | 282
Decreased muscle mass 1 | 28
Decreased pain sensation 1 | 17
Delayed Puberty 1 | 97
Delayed speech and language development 1 | 112
Dilated ventricles (finding) 1 | 121
Downturned corners of mouth 1 | 48
Dull intelligence 1 | 645
Failure to thrive in infancy 1 | 32
Flattening of cranial vault 1 | 20
Flattening of head 1 | 20
Gait, Unsteady 1 | 29
Generalized hypopigmentation 1 | 12
Generalized hypotonia 1 | 37
Hyperactive behavior 1 | 91
Hyperinsulinism 1 | 133
Hyperkyphosis 1 | 111
Hypernasal voice 1 | 39
Hyperopia 1 | 70
Hyperphagia 1 | 23
Hypertrophy of lower jaw 1 | 78
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplastic feet 1 | 66
Hypoplastic labia minora 1 | 10
Hypoventilation 1 | 8
Increased appetite (finding) 1 | 23
Increased size of mandible 1 | 78
Infantile onset 1 | 238
Infertility 1 | 188
Inflammatory bowel disease 1 | 151
Isolated cases 1 | 72
Isolated somatotropin deficiency 1 | 30
Kyphosis deformity of spine 1 | 114
Language Delay 1 | 112
Long narrow head 1 | 75
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 38 1 | 1
Mandibular hyperplasia 1 | 78
Mental and motor retardation 1 | 608
Motor delay 1 | 147
Narrow cranium shape 1 | 75
Narrow forehead 1 | 34
Narrow hands 1 | 6
Narrow head shape 1 | 75
Narrow nose 1 | 20
Narrow palate 1 | 20
Narrow skull shape 1 | 75
Nasal voice 1 | 39
No development of motor milestones 1 | 147
Obesity, Abdominal 1 | 24
Ocular albinism 1 | 26
Oculocutaneous albinism 1 | 29
Oligomenorrhea 1 | 16
Photosensitivity of skin 1 | 51
Physical aggression 1 | 76
Pick disease 1 | 1,894
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Plagiocephaly 1 | 20
Plagiocephaly, Nonsynostotic 1 | 20
Poor gross motor coordination 1 | 6
Poor suck 1 | 17
Prader-Willi syndrome 1 | 48
Recurrent respiratory infections 1 | 141
Reduced fetal movement 1 | 51
Respiratory Depression 1 | 10
Rhomboid shaped head 1 | 20
Sandal gap 1 | 24
Schizophrenia 1 | 1,160
Self Mutilation 1 | 14
Short hands 1 | 50
Sleep Apnea Syndromes 1 | 13
Small hand 1 | 36
Specific learning disability 1 | 47
Speech Delay 1 | 112
Speech impairment 1 | 112
Strabismus 1 | 270
Thin upper lip vermilion 1 | 67
Turridolichocephaly 1 | 75
Vitiligo 1 | 73
blue iris (physical finding) 1 | 17
glioblastoma 1 | 5,792
mandibular excess (physical finding) 1 | 78
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Enzyme 1 | 4,145

OMIM Phenotype

Mental retardation, autosomal ... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase HERC2 HERC2 Tbio Enzyme -1.25001 18.4 38