Development Level

Tbio 1 | 11,445

Disease

Abnormality of cardiac ventricle 1 | 1
Abnormality of position of teeth 1 | 8
Abnormality of the iris 1 | 14
Acromicric Dysplasia 1 | 5
Aneurysm of ascending aorta 1 | 5
Aortic Aneurysm, Thoracic 1 | 8
Aortic Rupture 1 | 5
Aortic aneurysm, familial thoracic 3 1 | 13
Aortic root dilatation 1 | 11
Aortic valve stenosis 1 | 28
Ascending aorta dilatation 1 | 5
Ascending aortic dissection 1 | 13
Broad metacarpals 1 | 5
Broad metatarsals 1 | 5
Broad phalanges of the hand 1 | 2
Broad ribs 1 | 12
Broad skull 1 | 2
Bullet vertebral body 1 | 17
Bullous keratopathy 1 | 7
Cone-shaped epiphyses 1 | 24
Crumpled ear 1 | 3
Cutis marmorata 1 | 32
Cystic medial necrosis of aorta 1 | 13
Decreased muscle mass 1 | 28
Decreased subcutaneous adipose tissue 1 | 13
Deep philtrum 1 | 21
Depressed philtrum 1 | 21
Descending aortic dissection 1 | 13
Diaphragmatic eventration 1 | 11
Diffusely thickened skin 1 | 20
Dissection of aorta 1 | 9
Dural ectasia 1 | 4
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
ECTOPIA LENTIS 1, ISOLATED, AUTOSOMAL DOMINANT 1 | 1
Echocardiogram abnormal 1 | 2
Ectopia lentis, isolated, autosomal dominant 1 | 1
Enlarged thorax 1 | 18
Eyebrow abnormalities 1 | 12
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Fifth metacarpal notched on ulnar side 1 | 1
GELEOPHYSIC DYSPLASIA 2 1 | 1
GEMSS syndrome 1 | 1
Geleophysic dysplasia 1 | 3
Genu recurvatum 1 | 12
Hammer Toe 1 | 23
Heart murmur 1 | 5
Hypoplasia of iris 1 | 10
Hypoplasia of thumb 1 | 26
Hypoxemia 1 | 2
Impaired left ventricular function 1 | 16
Incisional hernia 1 | 1
Increased arm span 1 | 2
Increased axial globe length 1 | 2
Iridodonesis 1 | 1
Isolated ectopia lentis 1 | 2
Lack of skin elasticity 1 | 10
Left-Sided Heart Failure 1 | 16
Lipoatrophy 1 | 19
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Loeys-Dietz syndrome 1 | 23
Long toes 1 | 5
MARFAN LIPODYSTROPHY SYNDROME 1 | 1
MASS syndrome 1 | 1
Marfan Syndrome 1 | 15
Marfanoid body habitus 1 | 11
Medial rotation of the medial malleolus 1 | 1
Misalignment of teeth 1 | 8
Narrow palate 1 | 20
Neonatal Marfan syndrome 1 | 1
OVERLAP CONNECTIVE TISSUE DISEASE 1 | 1
Organ system cancer 1 | 18
Ovoid vertebral bodies 1 | 17
Pachyderma 1 | 20
Pneumothorax 1 | 23
Premature calcification of mitral annulus 1 | 1
Premature osteoarthritis 1 | 6
Proportionate short stature 1 | 4
Protrusio acetabuli 1 | 7
Recurrent abdominal hernia 1 | 1
Severe myopia 1 | 22
Shallow anterior chamber of eye 1 | 4
Short phalanx of finger 1 | 32
Short tubular bones 1 | 22
Shprintzen-Goldberg Craniosynostosis Syndrome 1 | 3
Shprintzen-Goldberg syndrome 1 | 2
Spade-like hand 1 | 16
Spinal canal stenosis 1 | 12
Spondylolisthesis 1 | 22
Stiff Skin Syndrome 1 | 1
Stiff skin 1 | 3
Stretched skin 1 | 10
Talipes Calcaneovarus 1 | 2
Thoracic aortic aneurysm 1 | 15
Toe-walking gait 1 | 4
Tracheal stenosis 1 | 23
Tricuspid Valve Prolapse 1 | 3
Tricuspid valve insufficiency 1 | 14
Weill-Marchesani syndrome 2 1 | 1
Widened metatarsal shaft 1 | 5

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Non-IDG 1 | 12,091

OMIM Phenotype

Marfan lipodystrophy syndrome 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325