Development Level

Tbio 1 | 11,445

Disease

ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
ATRIAL SEPTAL DEFECT 7 WITH OR WITHOUT ATRIOVENTRICULAR CONDUCTION DEFECTS 1 | 1
Abdomen distended 1 | 43
Abnormal nasal morphology 1 | 16
Abnormality of metabolism/homeostasis 1 | 134
Asplenia, isolated congenital 1 | 2
Athyreosis 1 | 4
Athyroidal hypothyroidism 1 | 5
Atrial Fibrillation 1 | 124
Atrial heart septal defect 1 | 18
Atrioventricular Septal Defect 1 | 22
Atrioventricular block 1 | 35
Bilateral fifth finger clinodactyly 1 | 110
Brachydactyly 1 | 156
Broad forehead 1 | 59
Broad hallux 1 | 29
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomegaly 1 | 116
Cardiomyopathy 1 | 116
Cardiomyopathy, Dilated 1 | 83
Chromosome 5, monosomy 5q35 1 | 2
Coarse facial features 1 | 108
Conduction disorder of the heart 1 | 79
Congenital atresia of aortic valve 1 | 1
Congenital atresia of mitral valve 1 | 2
Congenital heart disease 1 | 93
Congenital hypoplasia of aortic arch 1 | 2
Congenital hypothyroidism 1 | 26
Conotruncal Heart Malformations 1 | 10
Constipation 1 | 181
Curvature of little finger 1 | 110
Discordant ventriculoarterial connection 1 | 17
Double Outlet Right Ventricle 1 | 11
Dyschezia 1 | 135
EKG abnormalities 1 | 78
Ebstein anomaly 1 | 16
Ectopic thyroid tissue (disorder) 1 | 2
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Exophthalmos 1 | 112
Familial atrial fibrillation 1 | 23
Familial progressive cardiac conduction defect 1 | 4
Fatigue 1 | 182
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
HYPOTHYROIDISM, CONGENITAL, DUE TO THYROID DYSGENESIS 1 | 4
HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 5 (disorder) 1 | 1
Heart Septal Defects, Ventricular 1 | 6
Hereditary bundle branch system defect 1 | 4
Holt-Oram syndrome 1 | 12
Hypersomnia 1 | 8
Hypertrophic pyloric stenosis 1 | 3
Hypoplastic Left Heart Syndrome 1 | 14
Hypoplastic Left Heart Syndrome 2 1 | 1
Hypothyroidism 1 | 122
Hypothyroidism, congenital, nongoitrous, 5 1 | 1
Icterus 1 | 82
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Long narrow head 1 | 75
Macroglossia 1 | 65
Muscle Weakness 1 | 170
Myocardial Infarction 1 | 151
Myotonic Dystrophy 1 | 3
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Ostium secundum atrial septal defect 1 | 9
POLYDACTYLY, POSTAXIAL 1 | 13
Persistant truncus arteriosus 1 | 17
Poor growth 1 | 114
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Progressive mental retardation 1 | 37
Prolonged PR interval 1 | 1
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Right atrial isomerism 1 | 29
Severe mental retardation (I.Q. 20-34) 1 | 99
Splenic Hypoplasia 1 | 2
Tetralogy of Fallot 1 | 63
Thickened facial skin with coarse facial features 1 | 108
Thin lips 1 | 49
Thyroid Agenesis 1 | 5
Thyroid Hypoplasia 1 | 4
Thyroid ectopia 1 | 2
Tricuspid atresia 1 | 7
Turridolichocephaly 1 | 75
Underdeveloped brows 1 | 38
Underdeveloped supraorbital ridges 1 | 38
VENTRICULAR SEPTAL DEFECT 3 1 | 1
Ventricular Septal Defects 1 | 119
Very poor growth 1 | 114
Wide bregma sutures 1 | 46
ventricular septal defect 1 | 20

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Female tissues 1 | 17,400
Urinary Tract 1 | 16,678

Target Family

Transcription Factor 1 | 1,400

OMIM Phenotype

Hypoplastic left heart syndrom... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385