Development Level

Tbio 1 | 11,445

IMPC Phenotype

abnormal retina morphology 1 | 71
decreased caudal vertebrae num... 1 | 53
increased bone mineral density 1 | 72
preweaning lethality, incomple... 1 | 499

Disease

Abnormal coordination 1 | 15
Absent speech 1 | 43
Acquired flat foot 1 | 72
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Astigmatism 1 | 54
Autonomic nervous system disorders 1 | 19
Bipolar Disorder 1 | 666
Broad flat nasal bridge 1 | 236
Cancer 1 | 2,499
Capuchin ears 1 | 17
Chromosome 18q deletion syndrome 1 | 10
Clubbing 1 | 9
Coarse facial features 1 | 108
Constipation 1 | 181
Corneal Dystrophy, Fuchs Endothelial, 3 1 | 1
Corneal disease 1 | 31
Craniofacial Abnormalities 1 | 151
Cupped ears (finding) 1 | 17
Duchenne muscular dystrophy 1 | 601
Dysautonomia 1 | 20
Dyschezia 1 | 135
Encephalopathies 1 | 43
Enophthalmos 1 | 75
Epilepsy 1 | 792
Flatfoot 1 | 73
Fuchs Endothelial Dystrophy 1 | 5
Fuchs' endothelial dystrophy 1 | 24
Gait Ataxia 1 | 51
Gastroesophageal reflux disease 1 | 110
Gastrointestinal system disease 1 | 54
Heart Diseases 1 | 43
Heartburn 1 | 78
Hypoplasia of corpus callosum 1 | 90
Intermittent hyperventilation 1 | 2
Liver Cirrhosis, Experimental 1 | 769
Liver neoplasms 1 | 130
Melanoma 1 | 711
Microcephaly 1 | 166
Motor delay 1 | 147
Myopia 1 | 176
Narrow foot 1 | 3
Narrow forehead 1 | 34
Nasal bridge wide 1 | 236
Neurodevelopmental Disorders 1 | 70
No development of motor milestones 1 | 147
Nonorganic psychosis 1 | 84
Open mouth 1 | 45
Paranoia 1 | 20
Parkinson's disease 1 | 392
Peripheral Nervous System Diseases 1 | 52
Peripheral Neuropathy 1 | 134
Physical aggression 1 | 76
Pick disease 1 | 1,894
Pitt-Hopkins syndrome 1 | 20
Polycystic ovary syndrome 1 | 360
Primary sclerosing cholangitis 1 | 14
Progressive mental retardation 1 | 37
Psychotic Disorders 1 | 151
Retinal disease 1 | 25
Schizophrenia 1 | 1,160
Seizures 1 | 596
Severe mental retardation (I.Q. 20-34) 1 | 99
Short philtrum 1 | 53
Single transverse palmar crease 1 | 29
Skin cancer 1 | 469
Strabismus 1 | 270
Sunken eyes 1 | 63
Tapering fingers (finding) 1 | 25
Thickened facial skin with coarse facial features 1 | 108
Upward slant of palpebral fissure 1 | 75
Widely spaced teeth 1 | 31
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
gastric carcinoma 1 | 807
head and neck cancer 1 | 271
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
nephrosclerosis 1 | 333
nonverbal 1 | 43
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
primary Sjogren syndrome 1 | 735
psoriasis 1 | 6,694
pterygium 1 | 76
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Transcription Factor 1 | 1,400

OMIM Phenotype

Corneal dystrophy, Fuchs endot... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor 4 TCF4 Tbio Transcription Factor -2.57908 320.1 249