Development Level

Tbio 1 | 11,445

IMPC Phenotype

abnormal adrenal gland morphol... 1 | 1
abnormal epididymis morphology 1 | 42
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Acquired scoliosis 1 | 281
Alzheimer's disease 1 | 658
Astrocytoma, Pilocytic 1 | 3,081
Autosomal recessive predisposition 1 | 1,442
Axonal degeneration/regeneration 1 | 7
Axonal regeneration 1 | 3
Basal lamina 'onion bulb' formations on nerve biopsy 1 | 1
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2K 1 | 1
CHARCOT-MARIE-TOOTH DISEASE, TYPE 4A (disorder) 1 | 1
CNS hypomyelination 1 | 17
Charcot-Marie-Tooth Disease, Axonal, With Vocal Cord Paresis, Autosomal Recessive 1 | 1
Charcot-Marie-Tooth Disease, Recessive Intermediate A 1 | 1
Charcot-Marie-Tooth Disease, Type 4A 1 | 1
Charcot-Marie-Tooth disease 1 | 62
Charcot-Marie-Tooth disease axonal type 2K 1 | 2
Charcot-Marie-Tooth disease, Type 2H 1 | 1
Charcot-Marie-Tooth disease, Type 2K 1 | 2
Charcot-Marie-Tooth disease, Type 4A, axonal form 1 | 2
Childhood onset 1 | 38
Claw hand 1 | 26
Congenital clubfoot 1 | 109
Congenital pes cavus 1 | 88
Contracture 1 | 96
Contracture of joint 1 | 93
Curvature of spine 1 | 282
Decreased motor NCV 1 | 22
Decreased number of large and small myelinated fibers 1 | 20
Decreased tendon reflex 1 | 122
Deformity of spine 1 | 1
Depletion of large myelinated fibers 1 | 7
Distal amyotrophy 1 | 51
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Distal sensory impairment 1 | 52
EMG: neuropathic changes 1 | 15
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Hammer Toe 1 | 23
Hoarse voice due to vocal cord paresis 1 | 3
Hypertrophic nerve changes 1 | 5
Hypomyelination 1 | 17
Inability to walk by childhood/adolescence 1 | 1
Infantile onset 1 | 238
Kyphoscoliosis deformity of spine 1 | 60
Motor delay 1 | 147
Muscle weakness of limb 1 | 21
Neonatal onset 1 | 21
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
No development of motor milestones 1 | 147
Obesity 1 | 678
Onion bulb formation 1 | 19
Partial Paralysis (Paresis) Vocal Cords 1 | 3
Peripheral Neuropathy 1 | 134
Peripheral axonal degeneration 1 | 4
Peripheral demyelination 1 | 16
Peripheral hypomyelination 1 | 7
Pick disease 1 | 1,894
Polyneuropathy 1 | 64
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Reflex, Deep Tendon, Absent 1 | 92
Rheumatoid arthritis 1 | 1,191
Ulnar claw 1 | 6
Vocal cord paresis in severe cases 1 | 3
Weakness of vocal cord 1 | 3
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
juvenile dermatomyositis 1 | 1,187
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
medulloblastoma 1 | 720
medulloblastoma, large-cell 1 | 6,241
ovarian cancer 1 | 8,520
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Non-IDG 1 | 12,091

OMIM Phenotype

Charcot-Marie-Tooth disease, a... 1 | 1
Abacavir hypersensitivity, sus... 35 | 35
Phenotype: {Spondyloarthropath... 35 | 35
Stevens-Johnson syndrome, susc... 35 | 35
Synovitis, chronic, susceptibi... 35 | 35
Toxic epidermal necrolysis, su... 35 | 35
Phenotype: {Hypersensitivity s... 21 | 21
HIV-1 viremia, susceptibility ... 14 | 14
Phenotype: {Psoriasis suscepti... 14 | 14
Multiple sclerosis, susceptibi... 13 | 13
Phenotype: {Sarcoidosis, susce... 13 | 13
Colorectal cancer, somatic 8 | 8
Gastric cancer, somatic 6 | 6
Diabetes mellitus, noninsulin-... 5 | 5
Pheochromocytoma 5 | 5
ACTH-independent macronodular ... 4 | 4
Alzheimer disease, susceptibil... 4 | 4
Malaria, resistance to 4 | 4
McCune-Albright syndrome, soma... 4 | 4
Mycobacterium tuberculosis, su... 4 | 4
Osseous heteroplasia, progress... 4 | 4
Phenotype: Colorectal cancer, ... 4 | 4
Phenotype: Pseudohypoparathyro... 4 | 4
Phenotype: [Blood group 4 | 4
Phenotype: {Myocardial infarct... 4 | 4
Phenotype: {Schizophrenia, sus... 4 | 4
Pituitary adenoma 3, multiple ... 4 | 4
Pseudohypoparathyroidism Ib 4 | 4
Pseudohypoparathyroidism Ic 4 | 4
Pseudopseudohypoparathyroidism 4 | 4
Renal tubular dysgenesis 4 | 4
Tetralogy of Fallot 4 | 4
Afibrinogenemia, congenital 3 | 3
Aplastic anemia 3 | 3
Bladder cancer, somatic 3 | 3
COACH syndrome 3 | 3
Central hypoventilation syndro... 3 | 3
Dejerine-Sottas disease 3 | 3
Diabetes mellitus, permanent n... 3 | 3
LADD syndrome 3 | 3
Leukemia, acute myeloid 3 | 3
Lung cancer, susceptibility to 3 | 3
Mismatch repair cancer syndrom... 3 | 3
Multiple pterygium syndrome, l... 3 | 3
Myocardial infarction, suscept... 3 | 3
Neuropathy, distal hereditary ... 3 | 3
Omenn syndrome 3 | 3
Paraganglioma and gastric stro... 3 | 3
Parkinson disease, susceptibil... 3 | 3
Phenotype: Anterior segment dy... 3 | 3
Phenotype: Bethlem myopathy 1 3 | 3
Phenotype: Dysfibrinogenemia, ... 3 | 3
Phenotype: Epilepsy, progressi... 3 | 3
Phenotype: Leigh syndrome due ... 3 | 3
Phenotype: Orthostatic intoler... 3 | 3
Phenotype: {Breast cancer, sus... 3 | 3
Prostate cancer, susceptibilit... 3 | 3
Retinitis punctata albescens 3 | 3
Roussy-Levy syndrome 3 | 3
Schimmelpenning-Feuerstein-Mim... 3 | 3
Schizencephaly 3 | 3
Ullrich congenital muscular dy... 3 | 3
Arthrogryposis, distal, type 2... 2 | 2
Asthma, susceptibility to 2 | 2
Brachydactyly, type A2 2 | 2
Cerebrooculofacioskeletal synd... 2 | 2
De Sanctis-Cacchione syndrome 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Epidermolysis bullosa simplex,... 2 | 2
Hypercholesterolemia, familial... 2 | 2
Hypofibrinogenemia, congenital 2 | 2
Ichthyosis, cyclic, with epide... 2 | 2
Jackson-Weiss syndrome 2 | 2
Leukemia, acute lymphoblastic,... 2 | 2
Leukemia, acute myeloid, somat... 2 | 2
Macular degeneration, age-rela... 2 | 2
Melanoma, cutaneous malignant,... 2 | 2
Microvascular complications of... 2 | 2
Ovarian cancer, somatic 2 | 2
Phenotype: Cockayne syndrome, ... 2 | 2
Phenotype: Epidermodysplasia v... 2 | 2
Phenotype: Epidermolysis bullo... 2 | 2
Phenotype: Epidermolytic hyper... 2 | 2
Phenotype: Hemochromatosis 2 | 2
Phenotype: Lacticacidemia due ... 2 | 2
Phenotype: Meesmann corneal dy... 2 | 2
Phenotype: Obesity, severe 2 | 2
Phenotype: Paroxysmal nonkines... 2 | 2
Phenotype: T-cell immunodefici... 2 | 2
Phenotype: Vitreoretinopathy, ... 2 | 2
Phenotype: {Alcohol dependence... 2 | 2
Phenotype: {Diabetes mellitus,... 2 | 2
Phenotype: {Nephrolithiasis, u... 2 | 2
Pick disease 2 | 2
Porphyria cutanea tarda, susce... 2 | 2
Porphyria variegata, susceptib... 2 | 2
Premature ovarian failure 11 2 | 2
Restrictive dermopathy, lethal 2 | 2
UV-sensitive syndrome 1 2 | 2
[Transferrin serum level QTL2] 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ganglioside-induced differentiation-associated protein 1 GDAP1 Tbio Non-IDG -1.99050 105.9 77