Development Level

Tbio 1,167 | 11,445
Tchem 236 | 1,598
Tdark 110 | 6,588
Tclin 109 | 613

Collection

Ion Channel: IDG Consortium (T... 7 | 99
GPCR: IDG Consortium (Targets) 5 | 126
Kinase: IDG Consortium (Comple... 4 | 37
Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 198 | 979
preweaning lethality, incomple... 117 | 499
abnormal behavior 68 | 298
abnormal retina morphology 64 | 71
abnormal embryo size 56 | 220
embryonic lethality prior to t... 55 | 278
cataract 49 | 92
abnormal lens morphology 47 | 81
enlarged heart 46 | 210
decreased body weight 42 | 161
hypoactivity 42 | 132
decreased total body fat amoun... 41 | 207
abnormal bone structure 40 | 187
increased lean body mass 39 | 172
abnormal eye morphology 37 | 68
hyperactivity 37 | 148
decreased lean body mass 33 | 135
embryonic lethality prior to o... 33 | 239
decreased vertical activity 32 | 208
decreased bone mineral content 30 | 151
increased total body fat amoun... 30 | 134
decreased bone mineral density 29 | 126
increased circulating alkaline... 29 | 122
abnormal heart morphology 28 | 162
corneal opacity 27 | 32
abnormal cornea morphology 26 | 31
increased bone mineral content 26 | 108
short tibia 26 | 97
abnormal coat-hair pigmentatio... 25 | 64
decreased circulating glucose ... 25 | 126
increased startle reflex 25 | 112
anophthalmia 24 | 33
embryonic growth retardation 24 | 106
abnormal gait 23 | 69
edema 23 | 59
increased mean corpuscular vol... 23 | 92
prenatal lethality prior to he... 23 | 87
decreased body length 22 | 101
decreased circulating serum al... 22 | 82
increased bone mineral density 21 | 72
increased or absent threshold ... 21 | 101
persistence of hyaloid vascula... 21 | 33
abnormal retinal blood vessel ... 20 | 26
decreased circulating HDL chol... 20 | 68
decreased mean corpuscular vol... 20 | 79
abnormal retinal vasculature m... 19 | 27
decreased circulating choleste... 19 | 93
decreased circulating triglyce... 19 | 79
decreased hemoglobin content 19 | 68
impaired glucose tolerance 19 | 75
male infertility 19 | 123
abnormal seminal vesicle morph... 18 | 114
abnormal sleep behavior 18 | 70
decreased circulating total pr... 18 | 49
decreased grip strength 18 | 116
decreased prepulse inhibition 18 | 82
increased circulating HDL chol... 18 | 80
microphthalmia 18 | 26
abnormal craniofacial morpholo... 17 | 33
increased circulating choleste... 17 | 66
increased heart weight 17 | 62
limb grasping 17 | 41
abnormal cranium morphology 16 | 36
decreased circulating insulin ... 16 | 76
decreased fasted circulating g... 16 | 65
decreased lymphocyte cell numb... 16 | 83
improved glucose tolerance 16 | 79
increased fasted circulating g... 16 | 76
small superior vagus ganglion 16 | 74
abnormal bone mineralization 15 | 38
decreased caudal vertebrae num... 15 | 53
decreased startle reflex 15 | 75
increased neutrophil cell numb... 15 | 46
abnormal neural tube closure 14 | 46
decreased circulating amylase ... 14 | 28
increased circulating triglyce... 14 | 42
impaired pupillary reflex 13 | 26
increased mean corpuscular hem... 13 | 96
small testis 13 | 58
thrombocytopenia 13 | 56
abnormal behavioral response t... 12 | 66
cardiovascular system phenotyp... 12 | 36
decreased blood urea nitrogen ... 12 | 51
decreased total retina thickne... 12 | 17
hydrometra 12 | 53
increased hemoglobin content 12 | 45
increased leukocyte cell numbe... 12 | 47
abnormal snout morphology 11 | 23
abnormal spleen morphology 11 | 55
abnormal testis morphology 11 | 43
abnormal tooth morphology 11 | 24
decreased erythrocyte cell num... 11 | 62
decreased hematocrit 11 | 46
decreased leukocyte cell numbe... 11 | 73
enlarged lymph nodes 11 | 37
increased circulating sodium l... 11 | 71
increased monocyte cell number 11 | 63
increased red blood cell distr... 11 | 34
narrow eye opening 11 | 12
pallor 11 | 34

Disease

Carcinoma 1,163 | 11,493
ovarian cancer 877 | 8,520
osteosarcoma 779 | 7,950
psoriasis 699 | 6,694
medulloblastoma, large-cell 696 | 6,241
glioblastoma 674 | 5,792
lung cancer 598 | 4,740
atypical teratoid / rhabdoid tumor 596 | 5,112
ependymoma 550 | 4,679
Cancer 472 | 2,499
Breast cancer 461 | 3,578
group 3 medulloblastoma 448 | 4,104
malignant mesothelioma 412 | 3,232
adult high grade glioma 409 | 3,801
invasive ductal carcinoma 374 | 2,951
Astrocytoma, Pilocytic 364 | 3,081
Kidney cancer 360 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 359 | 2,955
primitive neuroectodermal tumor 359 | 3,035
oligodendroglioma 355 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 354 | 3,291
non-small cell lung cancer 350 | 2,890
lung carcinoma 344 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 334 | 2,989
Autosomal recessive predisposition 326 | 1,442
lung adenocarcinoma 326 | 2,716
pancreatic cancer 326 | 2,398
astrocytic glioma 308 | 2,597
interstitial cystitis 283 | 2,312
pituitary cancer 274 | 1,972
subependymal giant cell astrocytoma 267 | 2,287
Intellectual disability 257 | 1,016
ulcerative colitis 249 | 1,819
cystic fibrosis 233 | 1,696
Schizophrenia 230 | 1,160
breast carcinoma 230 | 1,638
tuberculosis 230 | 2,010
group 4 medulloblastoma 228 | 1,855
ductal carcinoma in situ 226 | 1,745
Pick disease 218 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 210 | 1,962
adrenocortical carcinoma 204 | 1,428
diabetes mellitus 202 | 1,728
Dull intelligence 199 | 645
Low intelligence 199 | 645
Mental Retardation 199 | 645
Mental deficiency 199 | 645
Poor school performance 199 | 645
colon cancer 198 | 1,478
Epilepsy 174 | 792
Obesity 166 | 678
Seizures 164 | 596
primary pancreatic ductal adenocarcinoma 164 | 1,109
astrocytoma 154 | 1,146
Cognitive delay 153 | 608
Global developmental delay 153 | 608
Mental and motor retardation 153 | 608
Rheumatoid arthritis 146 | 1,191
Short stature 146 | 531
Cataract 145 | 297
acute quadriplegic myopathy 145 | 1,158
juvenile dermatomyositis 145 | 1,187
Muscle hypotonia 143 | 571
spina bifida 143 | 1,074
pediatric high grade glioma 139 | 1,064
Nystagmus 135 | 317
cutaneous lupus erythematosus 130 | 1,057
Bipolar Disorder 128 | 666
Melanoma 125 | 711
gastric carcinoma 125 | 807
Liver Cirrhosis, Experimental 122 | 769
Breast Neoplasms 120 | 445
nasopharyngeal carcinoma 120 | 1,058
Atopic dermatitis 118 | 952
Lens Opacities 118 | 231
Mammary Neoplasms 116 | 425
Multiple myeloma 116 | 1,332
Alzheimer's disease 114 | 658
Retinitis Pigmentosa 113 | 226
Sensorineural Hearing Loss (disorder) 109 | 284
autosomal dominant Emery-Dreifuss muscular dystrophy 106 | 510
Prostatic Neoplasms 105 | 495
dermatomyositis 105 | 966
Down syndrome 103 | 499
Broad flat nasal bridge 100 | 236
Nasal bridge wide 100 | 236
Depressive disorder 99 | 409
Glaucoma 99 | 239
Liver cancer 99 | 604
esophageal adenocarcinoma 98 | 737
Strabismus 97 | 270
Kidney disease 95 | 430
Small head 95 | 374
Duchenne muscular dystrophy 93 | 601
Hypertension 93 | 396
medulloblastoma 93 | 720
Hypertensive disease 91 | 292
Cleft Palate 90 | 271
Cryptorchidism 89 | 296
non primary Sjogren syndrome sicca 88 | 891

Tissue

Endocrine System 1,588 | 18,159
Digestive Tract 1,546 | 17,369
Skin and soft tissues 1,545 | 17,230
Female tissues 1,533 | 17,400
Male tissues 1,523 | 17,142
Nervous System 1,520 | 16,725
Urinary Tract 1,503 | 16,678
Blood and immune system 1,502 | 16,909
Liver and Pancreas 1,494 | 16,750
Respiratory system 1,466 | 16,393
Cardiovascular System 1,385 | 15,192

Target Family

Non-IDG 815 | 12,091
Enzyme 322 | 4,145
Transcription Factor 209 | 1,400
Kinase 90 | 634
GPCR 48 | 408
Ion Channel 41 | 344
Transporter 39 | 473
Epigenetic 38 | 242
Nuclear Receptor 15 | 48
TF/Epigenetic 5 | 38

MGI Phenotype

vision-eye phenotype 1,622 | 1,622
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Zinc finger protein Helios IKZF2 Tbio Transcription Factor -1.26324 15.8 221
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221