Development Level

Tbio 1,011 | 10,625
Tchem 270 | 1,890
Tdark 99 | 7,003
Tclin 98 | 602

Collection

Eligible Ion Channel Proteins 8 | 117
Eligible Kinase Proteins 4 | 134
Eligible non-olfactory GPCR Proteins 4 | 143

IMPC Term

preweaning lethality, complete... 127 | 633
abnormal retina morphology 85 | 100
preweaning lethality, incomple... 67 | 260
abnormal lens morphology 60 | 73
abnormal behavior 54 | 226
decreased lean body mass 50 | 195
abnormal retinal pigmentation 49 | 61
decreased total body fat amoun... 42 | 186
decreased bone mineral content 40 | 157
decreased body weight 39 | 174
embryonic lethality prior to t... 37 | 187
abnormal bone structure 31 | 131
enlarged heart 31 | 111
hypoactivity 31 | 89
abnormal embryo size 29 | 112
increased circulating alkaline... 29 | 119
increased or absent threshold ... 28 | 128
abnormal eye morphology 27 | 38
decreased grip strength 27 | 123
decreased body length 26 | 108
decreased bone mineral density 26 | 126
decreased circulating HDL chol... 26 | 77
hyperactivity 26 | 108
cataract 24 | 26
decreased circulating choleste... 24 | 85
decreased circulating triglyce... 23 | 83
increased mean corpuscular vol... 23 | 91
increased lean body mass 22 | 107
short tibia 22 | 82
embryonic lethality prior to o... 21 | 148
corneal opacity 20 | 25
increased bone mineral content 20 | 92
abnormal coat/hair pigmentatio... 19 | 54
abnormal cornea morphology 19 | 24
decreased circulating glucose ... 19 | 121
abnormal gait 18 | 51
decreased circulating serum al... 18 | 79
increased grip strength 18 | 83
increased total body fat amoun... 18 | 57
persistence of hyaloid vascula... 18 | 22
abnormal bone mineralization 17 | 55
decreased hemoglobin content 17 | 53
increased sacral vertebrae num... 17 | 62
increased startle reflex 17 | 38
abnormal retinal blood vessel ... 16 | 18
abnormal sleep behavior 16 | 63
decreased rib number 16 | 59
prenatal lethality prior to he... 16 | 64
decreased mean corpuscular vol... 15 | 50
decreased total retina thickne... 15 | 20
limb grasping 15 | 35
abnormal retinal vasculature m... 14 | 15
decreased circulating total pr... 14 | 41
decreased lumbar vertebrae num... 14 | 62
decreased prepulse inhibition 14 | 52
impaired glucose tolerance 14 | 52
increased bone mineral density 14 | 52
decreased circulating amylase ... 13 | 24
decreased circulating insulin ... 13 | 75
increased circulating sodium l... 13 | 71
abnormal cranium morphology 12 | 32
anophthalmia 12 | 20
decreased fasted circulating g... 12 | 49
decreased startle reflex 12 | 48
hydrops fetalis 12 | 22
increased body weight 12 | 42
increased leukocyte cell numbe... 12 | 37
increased mean corpuscular hem... 12 | 93
male infertility 12 | 62
thrombocytopenia 12 | 46
decreased caudal vertebrae num... 11 | 49
decreased circulating alkaline... 11 | 41
decreased leukocyte cell numbe... 11 | 54
impaired pupillary reflex 11 | 14
increased circulating HDL chol... 11 | 63
increased circulating choleste... 11 | 53
increased circulating iron lev... 11 | 25
increased fasted circulating g... 11 | 68
increased hemoglobin content 11 | 45
abnormal behavioral response t... 10 | 52
abnormal heart morphology 10 | 51
abnormal locomotor activation 10 | 26
abnormal optic disc morphology 10 | 10
abnormal snout morphology 10 | 18
decreased erythrocyte cell num... 10 | 43
decreased heart weight 10 | 44
improved glucose tolerance 10 | 56
increased blood urea nitrogen ... 10 | 44
increased circulating chloride... 10 | 43
increased circulating potassiu... 10 | 31
increased circulating triglyce... 10 | 24
narrow eye opening 10 | 15
small testis 10 | 37
decreased T cell number 9 | 31
decreased circulating LDL chol... 9 | 37
increased circulating calcium ... 9 | 32
increased heart weight 9 | 37
increased hematocrit 9 | 36
straub tail 9 | 26
tremors 9 | 34

Disease

ovarian cancer 798 | 8,484
osteosarcoma 713 | 7,933
psoriasis 646 | 6,685
medulloblastoma, large-cell 638 | 6,234
glioblastoma 592 | 5,572
lung cancer 531 | 4,466
atypical teratoid / rhabdoid tumor 452 | 4,369
Cancer 435 | 2,346
malignant mesothelioma 367 | 3,162
Breast cancer 364 | 3,094
invasive ductal carcinoma 347 | 2,950
pilocytic astrocytoma 339 | 3,086
primitive neuroectodermal tumor 334 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 332 | 2,956
oligodendroglioma 329 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 325 | 3,289
lung carcinoma 317 | 2,844
non-small cell lung cancer 315 | 2,798
Carcinoma 312 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 308 | 2,988
lung adenocarcinoma 307 | 2,713
pediatric high grade glioma 305 | 2,712
pancreatic cancer 277 | 2,300
ependymoma 266 | 2,514
interstitial cystitis 263 | 2,299
ulcerative colitis 262 | 2,087
pituitary cancer 253 | 1,972
subependymal giant cell astrocytoma 244 | 2,287
group 4 medulloblastoma 241 | 1,875
astrocytic glioma 228 | 2,241
ductal carcinoma in situ 216 | 1,745
cystic fibrosis 213 | 1,665
breast carcinoma 211 | 1,614
adult high grade glioma 197 | 2,148
Pick disease 192 | 1,893
group 3 medulloblastoma 192 | 2,254
astrocytoma 188 | 1,493
adrenocortical carcinoma 187 | 1,427
colon cancer 185 | 1,475
sonic hedgehog group medulloblastoma 178 | 1,482
posterior fossa group A ependymoma 177 | 1,511
pancreatic ductal adenocarcinoma liver metastasis 176 | 1,795
diabetes mellitus 174 | 1,663
primary pancreatic ductal adenocarcinoma 171 | 1,271
tuberculosis 161 | 1,557
medulloblastoma 156 | 1,524
posterior fossa group B ependymoma 155 | 1,530
juvenile dermatomyositis 139 | 1,189
acute quadriplegic myopathy 136 | 1,157
Rheumatoid Arthritis 135 | 1,160
atypical teratoid/rhabdoid tumor 132 | 1,095
spina bifida 125 | 1,064
gastric carcinoma 123 | 832
Obesity 118 | 616
cutaneous lupus erythematosus 118 | 1,056
Intellectual disability 117 | 573
nasopharyngeal carcinoma 115 | 1,056
Atopic dermatitis 108 | 944
Mammary Neoplasms 107 | 410
Alzheimer's disease 106 | 644
Multiple myeloma 106 | 1,327
autosomal dominant Emery-Dreifuss muscular dystrophy 102 | 499
dermatomyositis 101 | 933
Down syndrome 100 | 548
Prostatic Neoplasms 94 | 471
esophageal adenocarcinoma 92 | 737
Retinitis pigmentosa 91 | 153
Duchenne muscular dystrophy 87 | 602
Kidney disease 87 | 396
Endometriosis 85 | 535
Schizophrenia 79 | 501
active Crohn's disease 78 | 918
fibroadenoma 77 | 557
Neurodegenerative disease 76 | 383
Vascular disease 76 | 281
non primary Sjogren syndrome sicca 76 | 840
progressive supranuclear palsy 76 | 674
aldosterone-producing adenoma 75 | 664
primary Sjogren syndrome 73 | 789
acute myeloid leukemia 72 | 780
Multiple Sclerosis 69 | 498
Asthma 68 | 349
Craniofacial Abnormalities 68 | 147
chronic rhinosinusitis 68 | 512
Parkinson's disease 67 | 364
Stomach Neoplasms 65 | 282
Heart disease 64 | 279
Amyotrophic Lateral Sclerosis 62 | 431
Atherosclerosis 62 | 275
Epilepsy 62 | 346
Lung Neoplasms 62 | 171
Hypertension 61 | 287
Waldenstrons macroglobulinemia 61 | 765
non-small cell lung carcinoma 61 | 413
Blindness 59 | 84
Cerebrovascular disease 59 | 231
pancreatic carcinoma 59 | 567
tuberculosis and treatment for 6 months 58 | 686
Autistic Disorder 57 | 320
IGA Glomerulonephritis 55 | 454

Tissue

Nervous System 1,471 | 18,561
Female tissues 1,465 | 18,647
Endocrine System 1,464 | 18,512
Digestive Tract 1,463 | 18,473
Urinary Tract 1,456 | 18,444
Liver and Pancreas 1,452 | 18,136
Skin and soft tissues 1,452 | 18,115
Male tissues 1,449 | 17,969
Blood and immune system 1,448 | 17,995
Cardiovascular System 1,448 | 17,958
Respiratory system 1,417 | 17,484

Target Family

Non-IDG 743 | 11,971
Enzyme 278 | 4,146
Transcription Factor 197 | 1,400
Kinase 86 | 634
GPCR 46 | 406
Ion Channel 38 | 341
Transporter 37 | 473
Epigenetic 35 | 242
Nuclear Receptor 14 | 48
TF/Epigenetic 4 | 38

MGI Term

vision/eye phenotype 1,478 | 1,478
mortality/aging 4,850 | 4,850
homeostasis/metabolism phenoty... 4,454 | 4,454
growth/size/body region phenot... 3,915 | 3,915
cellular phenotype 3,348 | 3,348
nervous system phenotype 3,201 | 3,201
behavior/neurological phenotyp... 3,192 | 3,192
immune system phenotype 3,148 | 3,148
hematopoietic system phenotype 3,145 | 3,145
cardiovascular system phenotyp... 2,448 | 2,448
endocrine/exocrine gland pheno... 2,084 | 2,084
skeleton phenotype 2,058 | 2,058
normal phenotype 1,916 | 1,916
reproductive system phenotype 1,873 | 1,873
integument phenotype 1,748 | 1,748
embryo phenotype 1,674 | 1,674
muscle phenotype 1,385 | 1,385
digestive/alimentary phenotype 1,292 | 1,292
respiratory system phenotype 1,291 | 1,291
liver/biliary system phenotype 1,160 | 1,160
renal/urinary system phenotype 1,157 | 1,157
craniofacial phenotype 1,077 | 1,077
limbs/digits/tail phenotype 1,011 | 1,011
neoplasm 918 | 918
adipose tissue phenotype 901 | 901
hearing/vestibular/ear phenoty... 692 | 692
pigmentation phenotype 459 | 459
taste/olfaction phenotype 142 | 142
obsolete other phenotype 69 | 69

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.00063 1061.1 65
NADH-ubiquinone oxidoreductase chain 6 MT-ND6 Tclin Enzyme -2.74395 585.6 62
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0