Development Level

Tbio 96 | 11,445
Tchem 28 | 1,598
Tclin 16 | 613
Tdark 7 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 8 | 499
enlarged heart 5 | 210
decreased vertical activity 4 | 208
increased circulating alkaline... 3 | 122
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased lean body mass 2 | 135
edema 2 | 59
embryonic lethality prior to t... 2 | 278
enlarged spleen 2 | 41
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
limb grasping 2 | 41
male infertility 2 | 123
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
decreased B cell number 1 | 5
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
enlarged thymus 1 | 5
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
mammalian phenotype 1 | 17
small kidney 1 | 16
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 107 | 11,493
psoriasis 67 | 6,694
medulloblastoma, large-cell 62 | 6,241
ovarian cancer 58 | 8,520
osteosarcoma 56 | 7,950
glioblastoma 52 | 5,792
ependymoma 50 | 4,679
atypical teratoid / rhabdoid tumor 49 | 5,112
Breast cancer 41 | 3,578
lung cancer 40 | 4,740
malignant mesothelioma 39 | 3,232
Cancer 38 | 2,499
Astrocytoma, Pilocytic 34 | 3,081
Schizophrenia 34 | 1,160
group 3 medulloblastoma 34 | 4,104
oligodendroglioma 33 | 2,850
adult high grade glioma 32 | 3,801
invasive ductal carcinoma 31 | 2,951
Kidney cancer 30 | 2,613
pituitary cancer 30 | 1,972
Obesity 29 | 678
primitive neuroectodermal tumor 29 | 3,035
Intellectual disability 28 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
lung carcinoma 28 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
Autosomal recessive predisposition 24 | 1,442
astrocytic glioma 24 | 2,597
pancreatic cancer 24 | 2,398
Cognitive delay 23 | 608
Global developmental delay 23 | 608
Mental and motor retardation 23 | 608
diabetes mellitus 23 | 1,728
interstitial cystitis 23 | 2,312
lung adenocarcinoma 23 | 2,716
Dull intelligence 22 | 645
Epilepsy 22 | 792
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
Seizures 22 | 596
non-small cell lung cancer 22 | 2,890
cystic fibrosis 21 | 1,696
Bipolar Disorder 20 | 666
Short stature 19 | 531
breast carcinoma 19 | 1,638
group 4 medulloblastoma 19 | 1,855
colon cancer 18 | 1,478
ductal carcinoma in situ 17 | 1,745
medulloblastoma 17 | 720
subependymal giant cell astrocytoma 17 | 2,287
Muscle hypotonia 16 | 571
Parkinson's disease 16 | 392
adrenocortical carcinoma 16 | 1,428
nasopharyngeal carcinoma 16 | 1,058
tuberculosis 16 | 2,010
Alzheimer's disease 15 | 658
Pick disease 15 | 1,894
Strabismus 15 | 270
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Cleft Palate 14 | 271
Cryptorchidism 14 | 296
Alcoholic Intoxication, Chronic 13 | 289
Autistic Disorder 13 | 364
Depressive disorder 13 | 409
Cerebellar Ataxia 12 | 304
Liver cancer 12 | 604
Mental Depression 12 | 333
cutaneous lupus erythematosus 12 | 1,057
juvenile dermatomyositis 12 | 1,187
Amyotrophic lateral sclerosis 11 | 451
Atopic dermatitis 11 | 952
Breast Neoplasms 11 | 445
Congenital hypoplasia of penis 11 | 176
Constipation 11 | 181
Craniofacial Abnormalities 11 | 151
Holoprosencephaly 11 | 56
Melanoma 11 | 711
Nystagmus 11 | 317
Polydactyly 11 | 107
Skin cancer 11 | 469
astrocytoma 11 | 1,146
esophageal adenocarcinoma 11 | 737
Mammary Neoplasms 10 | 425
Nerve Degeneration 10 | 121
Neurodegenerative disease 10 | 414
Small head 10 | 374
pediatric high grade glioma 10 | 1,064
spina bifida 10 | 1,074
ulcerative colitis 10 | 1,819
Acquired scoliosis 9 | 281
Asthma 9 | 385
Attention deficit hyperactivity disorder 9 | 278
Curvature of spine 9 | 282
Lung Neoplasms 9 | 232
Retinitis Pigmentosa 9 | 226
Toxic encephalopathy 9 | 141
acute quadriplegic myopathy 9 | 1,158

Tissue

Endocrine System 137 | 18,159
Digestive Tract 129 | 17,369
Skin and soft tissues 126 | 17,230
Nervous System 125 | 16,725
Female tissues 124 | 17,400
Blood and immune system 123 | 16,909
Liver and Pancreas 120 | 16,750
Urinary Tract 120 | 16,678
Male tissues 118 | 17,142
Respiratory system 113 | 16,393
Cardiovascular System 98 | 15,192

Target Family

Non-IDG 51 | 12,091
Transcription Factor 35 | 1,400
Enzyme 22 | 4,145
Ion Channel 14 | 344
GPCR 11 | 408
Kinase 5 | 634
Transporter 4 | 473
oGPCR 4 | 421
Nuclear Receptor 1 | 48

MGI Phenotype

taste-olfaction phenotype 147 | 147
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
POU domain, class 2, transcription factor 3 POU2F3 Tbio Transcription Factor -2.50813 322.4 96
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Ectonucleoside triphosphate diphosphohydrolase 2 ENTPD2 Tchem Enzyme -2.37613 245.8 150
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Neuron navigator 2 NAV2 Tbio Non-IDG -1.59478 40.0 57