Development Level

Tbio 90 | 10,625
Tchem 30 | 1,890
Tclin 15 | 602
Tdark 7 | 7,003

Collection

Eligible Ion Channel Proteins 4 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, incomple... 7 | 260
preweaning lethality, complete... 6 | 633
increased circulating alkaline... 4 | 119
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
decreased rib number 3 | 59
enlarged heart 3 | 111
abnormal behavior 2 | 226
abnormal tooth morphology 2 | 24
decreased body weight 2 | 174
hypoactivity 2 | 89
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
limb grasping 2 | 35
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal digit morphology 1 | 13
abnormal ear morphology 1 | 5
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal seminal vesicle morph... 1 | 47
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
absent teeth 1 | 4
decreased B cell number 1 | 30
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
enlarged thymus 1 | 4
hydrometra 1 | 13
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
male infertility 1 | 62
small kidney 1 | 10
small superior vagus ganglion 1 | 20
tremors 1 | 34

Disease

psoriasis 64 | 6,685
medulloblastoma, large-cell 61 | 6,234
ovarian cancer 57 | 8,484
osteosarcoma 54 | 7,933
glioblastoma 48 | 5,572
atypical teratoid / rhabdoid tumor 42 | 4,369
lung cancer 38 | 4,466
malignant mesothelioma 37 | 3,162
Cancer 36 | 2,346
pilocytic astrocytoma 34 | 3,086
oligodendroglioma 32 | 2,849
Breast cancer 31 | 3,094
invasive ductal carcinoma 29 | 2,950
pituitary cancer 29 | 1,972
primitive neuroectodermal tumor 29 | 3,031
Carcinoma 28 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
lung carcinoma 27 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
Obesity 25 | 616
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
ependymoma 23 | 2,514
group 4 medulloblastoma 23 | 1,875
lung adenocarcinoma 22 | 2,713
non-small cell lung cancer 22 | 2,798
pediatric high grade glioma 22 | 2,712
cystic fibrosis 20 | 1,665
interstitial cystitis 20 | 2,299
Intellectual disability 19 | 573
adult high grade glioma 19 | 2,148
astrocytic glioma 19 | 2,241
diabetes mellitus 19 | 1,663
pancreatic cancer 19 | 2,300
posterior fossa group B ependymoma 19 | 1,530
medulloblastoma 18 | 1,524
sonic hedgehog group medulloblastoma 18 | 1,482
colon cancer 17 | 1,475
ductal carcinoma in situ 17 | 1,745
Parkinson's disease 16 | 364
breast carcinoma 16 | 1,614
nasopharyngeal carcinoma 16 | 1,056
Schizophrenia 15 | 501
adrenocortical carcinoma 15 | 1,427
group 3 medulloblastoma 15 | 2,254
subependymal giant cell astrocytoma 15 | 2,287
Pick disease 14 | 1,893
astrocytoma 14 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Alzheimer's disease 13 | 644
Autistic Disorder 13 | 320
posterior fossa group A ependymoma 13 | 1,511
tuberculosis 13 | 1,557
Epilepsy 12 | 346
juvenile dermatomyositis 12 | 1,189
cutaneous lupus erythematosus 11 | 1,056
esophageal adenocarcinoma 11 | 737
Amyotrophic Lateral Sclerosis 10 | 431
Atopic dermatitis 10 | 944
Holoprosencephaly 10 | 52
Mammary Neoplasms 10 | 410
Polydactyly 10 | 93
atypical teratoid/rhabdoid tumor 10 | 1,095
ulcerative colitis 10 | 2,087
Craniofacial Abnormalities 9 | 147
Lung Neoplasms 9 | 171
Nerve Degeneration 9 | 73
Toxic encephalopathy 9 | 131
acute quadriplegic myopathy 9 | 1,157
Down syndrome 8 | 548
Neuropathy 8 | 210
gastric carcinoma 8 | 832
nervous system disorder 8 | 53
spina bifida 8 | 1,064
Attention deficit hyperactivity disorder 7 | 156
Dementia 7 | 129
Fundus dystrophy 7 | 77
Kidney disease 7 | 396
Neurodegenerative disease 7 | 383
Retinitis pigmentosa 7 | 153
Seizures 7 | 95
aldosterone-producing adenoma 7 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
non-small cell lung carcinoma 7 | 413
primary pancreatic ductal adenocarcinoma 7 | 1,271
Acquired metabolic disease 6 | 267
Asthma 6 | 349
Bardet-Biedl Syndrome 6 | 40
Bipolar Disorder 6 | 266
Cleft palate 6 | 125
Coronary artery disease 6 | 240
Duchenne muscular dystrophy 6 | 602
Heart disease 6 | 279
Huntington's disease 6 | 72
Microphthalmia 6 | 78
Osteoporosis 6 | 257
Pain agnosia 6 | 99
Stomach Neoplasms 6 | 282
Waldenstrons macroglobulinemia 6 | 765
fibroadenoma 6 | 557
non primary Sjogren syndrome sicca 6 | 840

Tissue

Female tissues 139 | 18,647
Liver and Pancreas 138 | 18,136
Nervous System 138 | 18,561
Urinary Tract 138 | 18,444
Digestive Tract 137 | 18,473
Endocrine System 137 | 18,512
Cardiovascular System 135 | 17,958
Skin and soft tissues 134 | 18,115
Blood and immune system 132 | 17,995
Male tissues 130 | 17,969
Respiratory system 125 | 17,484

Target Family

Non-IDG 46 | 11,971
Transcription Factor 35 | 1,400
Enzyme 22 | 4,146
Ion Channel 14 | 341
GPCR 11 | 406
Kinase 5 | 634
Transporter 4 | 473
oGPCR 4 | 421
Nuclear Receptor 1 | 48

MGI Term

taste/olfaction phenotype 142 | 142
mortality/aging 4,850 | 4,850
homeostasis/metabolism phenoty... 4,454 | 4,454
growth/size/body region phenot... 3,915 | 3,915
cellular phenotype 3,348 | 3,348
nervous system phenotype 3,201 | 3,201
behavior/neurological phenotyp... 3,192 | 3,192
immune system phenotype 3,148 | 3,148
hematopoietic system phenotype 3,145 | 3,145
cardiovascular system phenotyp... 2,448 | 2,448
endocrine/exocrine gland pheno... 2,084 | 2,084
skeleton phenotype 2,058 | 2,058
normal phenotype 1,916 | 1,916
reproductive system phenotype 1,873 | 1,873
integument phenotype 1,748 | 1,748
embryo phenotype 1,674 | 1,674
vision/eye phenotype 1,478 | 1,478
muscle phenotype 1,385 | 1,385
digestive/alimentary phenotype 1,292 | 1,292
respiratory system phenotype 1,291 | 1,291
liver/biliary system phenotype 1,160 | 1,160
renal/urinary system phenotype 1,157 | 1,157
craniofacial phenotype 1,077 | 1,077
limbs/digits/tail phenotype 1,011 | 1,011
neoplasm 918 | 918
adipose tissue phenotype 901 | 901
hearing/vestibular/ear phenoty... 692 | 692
pigmentation phenotype 459 | 459
obsolete other phenotype 69 | 69

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.19758 165.4 232
Taste receptor type 1 member 1 TAS1R1 Tbio GPCR -1.71516 50.8 165
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
LIM/homeobox protein Lhx2 LHX2 Tbio Transcription Factor -1.89097 87.7 161
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.02060 88.8 104
Nuclear receptor ROR-alpha RORA Tchem Nuclear Receptor -2.17386 139.2 340
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188