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Development Level

Tbio 1,536 | 11,178
Tchem 381 | 1,885
Tdark 165 | 6,569
Tclin 140 | 612

Collection

Kinase: IDG Consortium (Target... 11 | 125
Ion Channel: IDG Consortium (T... 9 | 99
GPCR: IDG Consortium (Targets) 8 | 126
GPCR: IDG Consortium (Complete... 3 | 25
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 238 | 979
preweaning lethality, incomple... 151 | 499
abnormal bone structure 137 | 187
decreased bone mineral content 118 | 151
decreased total body fat amoun... 106 | 207
abnormal behavior 99 | 298
increased lean body mass 91 | 172
decreased body weight 87 | 161
decreased bone mineral density 85 | 126
decreased lean body mass 85 | 135
increased total body fat amoun... 81 | 134
increased circulating alkaline... 69 | 122
decreased body length 66 | 101
increased bone mineral content 64 | 108
short tibia 64 | 97
embryonic lethality prior to t... 59 | 278
abnormal embryo size 57 | 220
decreased circulating choleste... 48 | 93
decreased circulating glucose ... 47 | 126
enlarged heart 46 | 210
decreased vertical activity 44 | 208
embryonic lethality prior to o... 44 | 239
increased bone mineral density 44 | 72
hyperactivity 43 | 148
decreased circulating serum al... 40 | 82
hypoactivity 40 | 132
increased startle reflex 38 | 112
decreased caudal vertebrae num... 36 | 53
decreased grip strength 36 | 116
abnormal cranium morphology 35 | 36
decreased circulating HDL chol... 35 | 68
decreased circulating triglyce... 34 | 79
abnormal heart morphology 33 | 162
increased mean corpuscular hem... 33 | 96
male infertility 33 | 123
abnormal bone mineralization 32 | 38
abnormal gait 30 | 69
decreased circulating insulin ... 30 | 76
decreased hemoglobin content 30 | 68
increased heart weight 30 | 62
decreased prepulse inhibition 29 | 82
abnormal seminal vesicle morph... 28 | 114
decreased circulating total pr... 28 | 49
impaired glucose tolerance 28 | 75
increased circulating HDL chol... 28 | 80
increased circulating choleste... 27 | 66
increased mean corpuscular vol... 27 | 92
increased or absent threshold ... 27 | 101
decreased erythrocyte cell num... 26 | 62
thrombocytopenia 26 | 56
decreased circulating alkaline... 24 | 46
decreased leukocyte cell numbe... 24 | 73
abnormal tooth morphology 23 | 24
cataract 23 | 92
decreased lymphocyte cell numb... 23 | 83
decreased startle reflex 23 | 75
decreased circulating LDL chol... 22 | 38
prenatal lethality prior to he... 22 | 87
vertebral fusion 22 | 23
abnormal eye morphology 21 | 68
abnormal retina morphology 21 | 71
abnormal sleep behavior 21 | 70
corneal opacity 21 | 32
decreased circulating alanine ... 21 | 47
decreased mean corpuscular vol... 21 | 79
edema 21 | 59
improved glucose tolerance 21 | 79
increased blood urea nitrogen ... 21 | 48
increased hemoglobin content 21 | 45
abnormal coat-hair pigmentatio... 20 | 64
abnormal cornea morphology 20 | 31
abnormal lens morphology 20 | 81
abnormal snout morphology 20 | 23
decreased fasted circulating g... 20 | 65
increased circulating sodium l... 20 | 71
small superior vagus ganglion 20 | 74
decreased circulating calcium ... 19 | 36
increased grip strength 19 | 41
decreased blood urea nitrogen ... 18 | 51
decreased mean corpuscular hem... 18 | 50
increased circulating triglyce... 18 | 42
increased leukocyte cell numbe... 18 | 47
limb grasping 18 | 41
decreased circulating aspartat... 17 | 34
decreased hematocrit 17 | 46
increased circulating creatini... 17 | 38
increased circulating iron lev... 17 | 30
increased hematocrit 17 | 46
increased neutrophil cell numb... 17 | 46
tremors 17 | 39
abnormal maxilla morphology 16 | 17
abnormal spleen morphology 16 | 55
decreased circulating amylase ... 16 | 28
decreased circulating iron lev... 16 | 32
decreased heart weight 16 | 27
embryonic growth retardation 16 | 106
increased circulating chloride... 16 | 41
increased erythrocyte cell num... 16 | 39
increased fasted circulating g... 16 | 76
abnormal kidney morphology 15 | 65

Disease

Carcinoma 1,487 | 11,192
ovarian cancer 1,203 | 8,297
osteosarcoma 1,068 | 7,766
psoriasis 940 | 6,514
medulloblastoma, large-cell 880 | 6,086
glioblastoma 871 | 5,635
atypical teratoid / rhabdoid tumor 750 | 4,971
lung cancer 748 | 4,607
ependymoma 684 | 4,559
Breast cancer 629 | 3,469
Cancer 620 | 2,388
group 3 medulloblastoma 554 | 4,002
malignant mesothelioma 529 | 3,135
adult high grade glioma 516 | 3,701
Astrocytoma, Pilocytic 512 | 3,006
invasive ductal carcinoma 502 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 490 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 489 | 3,204
intraductal papillary-mucinous carcinoma (IPMC) 469 | 2,902
pancreatic cancer 461 | 2,322
Kidney cancer 459 | 2,548
non-small cell lung cancer 447 | 2,799
primitive neuroectodermal tumor 442 | 2,957
lung carcinoma 431 | 2,755
oligodendroglioma 419 | 2,768
lung adenocarcinoma 398 | 2,627
interstitial cystitis 381 | 2,237
astrocytic glioma 375 | 2,530
Autosomal recessive predisposition 370 | 1,407
ulcerative colitis 350 | 1,765
pituitary cancer 344 | 1,915
subependymal giant cell astrocytoma 325 | 2,230
tuberculosis 316 | 1,963
cystic fibrosis 301 | 1,629
breast carcinoma 288 | 1,589
diabetes mellitus 284 | 1,683
ductal carcinoma in situ 284 | 1,686
group 4 medulloblastoma 281 | 1,806
Pick disease 279 | 1,856
pancreatic ductal adenocarcinoma liver metastasis 279 | 1,911
Intellectual disability 259 | 998
colon cancer 256 | 1,428
Schizophrenia 252 | 1,136
adrenocortical carcinoma 248 | 1,385
Rheumatoid arthritis 227 | 1,156
primary pancreatic ductal adenocarcinoma 223 | 1,071
Short stature 219 | 514
juvenile dermatomyositis 212 | 1,147
astrocytoma 206 | 1,113
acute quadriplegic myopathy 205 | 1,133
Dull intelligence 194 | 634
Low intelligence 194 | 634
Mental Retardation 194 | 634
Mental deficiency 194 | 634
Poor school performance 194 | 634
pediatric high grade glioma 188 | 1,035
Obesity 184 | 655
Epilepsy 180 | 775
cutaneous lupus erythematosus 178 | 1,016
spina bifida 173 | 1,053
Multiple myeloma 169 | 1,296
Muscle hypotonia 169 | 562
Cognitive delay 167 | 596
Global developmental delay 167 | 596
Mental and motor retardation 167 | 596
gastric carcinoma 166 | 781
Liver Cirrhosis, Experimental 164 | 733
Seizures 161 | 584
dermatomyositis 153 | 941
nasopharyngeal carcinoma 152 | 1,024
Atopic dermatitis 151 | 915
Breast Neoplasms 144 | 423
Duchenne muscular dystrophy 143 | 587
Hypoplastic mandible condyle 142 | 273
Mandibular hypoplasia 142 | 273
Melanoma 142 | 689
Micrognathism 142 | 273
Osteoporosis 142 | 348
Cleft Palate 139 | 265
Liver cancer 138 | 589
Mammary Neoplasms 138 | 403
autosomal dominant Emery-Dreifuss muscular dystrophy 138 | 492
esophageal adenocarcinoma 134 | 696
Alzheimer's disease 133 | 640
Bipolar Disorder 133 | 646
Prostatic Neoplasms 133 | 472
active Crohn's disease 133 | 882
Kidney disease 132 | 411
non primary Sjogren syndrome sicca 128 | 861
Acquired scoliosis 125 | 274
Curvature of spine 125 | 275
Down syndrome 124 | 480
active ulcerative colitis 124 | 736
medulloblastoma 122 | 702
Depressive disorder 121 | 401
Small head 121 | 366
Orbital separation excessive 116 | 240
acute myeloid leukemia 116 | 760
Cryptorchidism 113 | 287
Endometriosis 109 | 521

Tissue

Endocrine System 2,175 | 18,159
Digestive Tract 2,138 | 17,369
Female tissues 2,126 | 17,400
Male tissues 2,124 | 17,142
Skin and soft tissues 2,122 | 17,230
Urinary Tract 2,089 | 16,678
Blood and immune system 2,077 | 16,909
Liver and Pancreas 2,072 | 16,750
Nervous System 2,067 | 16,725
Respiratory system 2,042 | 16,393
Cardiovascular System 1,917 | 15,192

Target Family

Non-IDG 1,086 | 12,091
Enzyme 449 | 4,145
Transcription Factor 310 | 1,400
Kinase 128 | 634
Epigenetic 68 | 242
GPCR 64 | 408
Transporter 54 | 473
Ion Channel 35 | 344
Nuclear Receptor 19 | 48
TF/Epigenetic 9 | 38

MGI Phenotype

skeleton phenotype 2,222 | 2,222
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Mitogen-activated protein kinase-binding protein 1 MAPKBP1 Tbio Enzyme -0.46630 4.01 51
Ryanodine receptor 1 RYR1 Tclin Ion Channel -3.00978 1018.9 103
Bone sialoprotein 2 IBSP Tbio Non-IDG -2.95483 756.8 261
Solute carrier family 22 member 8 SLC22A8 Tclin Transporter -2.40126 258.4 113
Tumor necrosis factor receptor superfamily member 1B TNFRSF1B Tchem Non-IDG -3.67481 4484.7 712
Bcl-2 homologous antagonist/killer BAK1 Tchem Non-IDG -2.29199 175.9 554