Development Level

Tbio 371 | 11,445
Tchem 70 | 1,598
Tdark 33 | 6,588
Tclin 32 | 613

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 54 | 979
abnormal coat-hair pigmentatio... 50 | 64
abnormal retina morphology 35 | 71
preweaning lethality, incomple... 33 | 499
enlarged heart 18 | 210
abnormal behavior 17 | 298
decreased body weight 15 | 161
decreased vertical activity 13 | 208
embryonic lethality prior to t... 13 | 278
increased lean body mass 13 | 172
abnormal embryo size 12 | 220
decreased circulating glucose ... 12 | 126
hypoactivity 12 | 132
abnormal bone structure 11 | 187
abnormal eye morphology 11 | 68
abnormal sleep behavior 11 | 70
decreased bone mineral density 11 | 126
decreased bone mineral content 10 | 151
decreased total body fat amoun... 10 | 207
embryonic lethality prior to o... 10 | 239
increased mean corpuscular vol... 10 | 92
abnormal heart morphology 9 | 162
decreased lean body mass 9 | 135
increased total body fat amoun... 9 | 134
corneal opacity 8 | 32
decreased circulating triglyce... 8 | 79
abnormal behavioral response t... 7 | 66
abnormal bone mineralization 7 | 38
abnormal cornea morphology 7 | 31
abnormal lens morphology 7 | 81
abnormal seminal vesicle morph... 7 | 114
decreased erythrocyte cell num... 7 | 62
decreased hemoglobin content 7 | 68
hyperactivity 7 | 148
increased bone mineral density 7 | 72
increased circulating alkaline... 7 | 122
increased fasted circulating g... 7 | 76
increased or absent threshold ... 7 | 101
male infertility 7 | 123
abnormal cranium morphology 6 | 36
abnormal skin morphology 6 | 50
cataract 6 | 92
decreased body length 6 | 101
decreased caudal vertebrae num... 6 | 53
decreased circulating HDL chol... 6 | 68
decreased circulating choleste... 6 | 93
decreased mean corpuscular vol... 6 | 79
decreased prepulse inhibition 6 | 82
embryonic growth retardation 6 | 106
increased hematocrit 6 | 46
increased mean corpuscular hem... 6 | 96
increased monocyte cell number 6 | 63
narrow eye opening 6 | 12
prenatal lethality prior to he... 6 | 87
small superior vagus ganglion 6 | 74
abnormal tooth morphology 5 | 24
decreased grip strength 5 | 116
decreased hematocrit 5 | 46
increased circulating choleste... 5 | 66
increased circulating triglyce... 5 | 42
increased hemoglobin content 5 | 45
increased startle reflex 5 | 112
mammalian phenotype 5 | 17
microphthalmia 5 | 26
vertebral fusion 5 | 23
abnormal gait 4 | 69
abnormal iris morphology 4 | 13
abnormal neural tube closure 4 | 46
abnormal pericardium morpholog... 4 | 26
abnormal placenta size 4 | 20
abnormal retinal blood vessel ... 4 | 26
abnormal retinal vasculature m... 4 | 27
abnormal snout morphology 4 | 23
absent pinna reflex 4 | 23
corneal vascularization 4 | 6
decreased circulating LDL chol... 4 | 38
decreased circulating chloride... 4 | 30
decreased circulating insulin ... 4 | 76
decreased circulating sodium l... 4 | 22
decreased circulating total pr... 4 | 49
decreased fasted circulating g... 4 | 65
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
decreased neutrophil cell numb... 4 | 42
decreased startle reflex 4 | 75
edema 4 | 59
female infertility 4 | 60
impaired pupillary reflex 4 | 26
increased body weight 4 | 25
increased circulating HDL chol... 4 | 80
increased circulating free fat... 4 | 20
increased circulating iron lev... 4 | 30
increased heart weight 4 | 62
increased mean corpuscular hem... 4 | 36
increased mean platelet volume 4 | 45
pale yolk sac 4 | 25
short tibia 4 | 97
anophthalmia 3 | 33
increased bone mineral content 3 | 108
increased circulating sodium l... 3 | 71

Disease

Carcinoma 359 | 11,493
ovarian cancer 280 | 8,520
osteosarcoma 256 | 7,950
psoriasis 218 | 6,694
medulloblastoma, large-cell 197 | 6,241
glioblastoma 186 | 5,792
lung cancer 180 | 4,740
atypical teratoid / rhabdoid tumor 172 | 5,112
ependymoma 161 | 4,679
Cancer 153 | 2,499
group 3 medulloblastoma 137 | 4,104
Breast cancer 136 | 3,578
malignant mesothelioma 125 | 3,232
Autosomal recessive predisposition 120 | 1,442
primitive neuroectodermal tumor 113 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 111 | 3,291
oligodendroglioma 111 | 2,850
Kidney cancer 109 | 2,613
invasive ductal carcinoma 109 | 2,951
non-small cell lung cancer 107 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 105 | 2,955
adult high grade glioma 103 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 99 | 2,989
Astrocytoma, Pilocytic 98 | 3,081
astrocytic glioma 94 | 2,597
Intellectual disability 91 | 1,016
pancreatic cancer 89 | 2,398
lung adenocarcinoma 87 | 2,716
lung carcinoma 85 | 2,843
pituitary cancer 85 | 1,972
interstitial cystitis 79 | 2,312
Dull intelligence 77 | 645
Low intelligence 77 | 645
Mental Retardation 77 | 645
Mental deficiency 77 | 645
Poor school performance 77 | 645
subependymal giant cell astrocytoma 77 | 2,287
ulcerative colitis 75 | 1,819
ductal carcinoma in situ 71 | 1,745
group 4 medulloblastoma 70 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 68 | 1,962
tuberculosis 67 | 2,010
breast carcinoma 65 | 1,638
Melanoma 63 | 711
Schizophrenia 63 | 1,160
cystic fibrosis 63 | 1,696
diabetes mellitus 63 | 1,728
Pick disease 62 | 1,894
Epilepsy 59 | 792
colon cancer 57 | 1,478
Obesity 55 | 678
Seizures 54 | 596
astrocytoma 54 | 1,146
Muscle hypotonia 53 | 571
Short stature 53 | 531
adrenocortical carcinoma 53 | 1,428
Nystagmus 51 | 317
Cataract 50 | 297
Cognitive delay 50 | 608
Global developmental delay 50 | 608
Mental and motor retardation 50 | 608
Sensorineural Hearing Loss (disorder) 50 | 284
acute quadriplegic myopathy 50 | 1,158
Lens Opacities 48 | 231
Strabismus 47 | 270
cutaneous lupus erythematosus 47 | 1,057
nasopharyngeal carcinoma 46 | 1,058
juvenile dermatomyositis 45 | 1,187
pediatric high grade glioma 45 | 1,064
spina bifida 45 | 1,074
Rheumatoid arthritis 43 | 1,191
Broad flat nasal bridge 42 | 236
Multiple myeloma 42 | 1,332
Nasal bridge wide 42 | 236
Prostatic Neoplasms 42 | 495
Skin cancer 42 | 469
primary pancreatic ductal adenocarcinoma 40 | 1,109
Small head 39 | 374
Low Vision 38 | 174
Photodysphoria 38 | 121
Photophobia 38 | 121
Visual Impairment 38 | 174
Breast Neoplasms 37 | 445
Glaucoma 37 | 239
Mammary Neoplasms 37 | 425
Optic Atrophy 37 | 242
non primary Sjogren syndrome sicca 37 | 891
Atopic dermatitis 36 | 952
Congenital hypoplasia of penis 36 | 176
Depressive disorder 36 | 409
gastric carcinoma 35 | 807
dermatomyositis 34 | 966
primary Sjogren syndrome 34 | 735
Bipolar Disorder 33 | 666
Liver Cirrhosis, Experimental 33 | 769
Liver cancer 33 | 604
Hypoplastic mandible condyle 32 | 275
Mandibular hypoplasia 32 | 275
Micrognathism 32 | 275
Retinitis Pigmentosa 32 | 226

Tissue

Endocrine System 494 | 18,159
Skin and soft tissues 485 | 17,230
Female tissues 483 | 17,400
Digestive Tract 480 | 17,369
Male tissues 479 | 17,142
Blood and immune system 473 | 16,909
Nervous System 472 | 16,725
Liver and Pancreas 467 | 16,750
Urinary Tract 465 | 16,678
Respiratory system 455 | 16,393
Cardiovascular System 436 | 15,192

Target Family

Non-IDG 258 | 12,091
Enzyme 112 | 4,145
Transcription Factor 57 | 1,400
Kinase 29 | 634
GPCR 16 | 408
Transporter 14 | 473
Ion Channel 9 | 344
Epigenetic 6 | 242
Nuclear Receptor 4 | 48
TF/Epigenetic 1 | 38

MGI Phenotype

pigmentation phenotype 506 | 506
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
LIM domain only protein 7 LMO7 Tbio Non-IDG -1.24771 19.7 80
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133