Development Level

Tbio 322 | 10,625
Tchem 73 | 1,890
Tdark 35 | 7,003
Tclin 29 | 602

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

abnormal coat/hair pigmentatio... 44 | 54
abnormal retinal pigmentation 43 | 61
preweaning lethality, complete... 35 | 633
abnormal retina morphology 31 | 100
preweaning lethality, incomple... 21 | 260
abnormal behavior 16 | 226
decreased body weight 12 | 174
decreased lean body mass 12 | 195
enlarged heart 12 | 111
abnormal eye morphology 10 | 38
decreased bone mineral content 10 | 157
decreased circulating glucose ... 10 | 121
decreased circulating triglyce... 10 | 83
abnormal bone mineralization 9 | 55
decreased total body fat amoun... 9 | 186
hypoactivity 9 | 89
increased circulating alkaline... 9 | 119
increased mean corpuscular vol... 9 | 91
abnormal sleep behavior 8 | 63
embryonic lethality prior to t... 8 | 187
abnormal behavioral response t... 7 | 52
abnormal bone structure 7 | 131
abnormal embryo size 7 | 112
decreased bone mineral density 7 | 126
increased body weight 7 | 42
narrow eye opening 7 | 15
abnormal lens morphology 6 | 73
corneal opacity 6 | 25
decreased body length 6 | 108
decreased caudal vertebrae num... 6 | 49
decreased circulating HDL chol... 6 | 77
decreased circulating choleste... 6 | 85
decreased hemoglobin content 6 | 53
embryonic lethality prior to o... 6 | 148
increased fasted circulating g... 6 | 68
increased mean corpuscular hem... 6 | 93
increased or absent threshold ... 6 | 128
abnormal cornea morphology 5 | 24
decreased circulating LDL chol... 5 | 37
decreased circulating amylase ... 5 | 24
decreased erythrocyte cell num... 5 | 43
decreased fasted circulating g... 5 | 49
decreased grip strength 5 | 123
decreased mean corpuscular vol... 5 | 50
hyperactivity 5 | 108
increased bone mineral density 5 | 52
increased grip strength 5 | 83
increased hematocrit 5 | 36
increased hemoglobin content 5 | 45
increased lean body mass 5 | 107
abnormal cranium morphology 4 | 32
abnormal gait 4 | 51
abnormal retinal vasculature m... 4 | 15
abnormal seminal vesicle morph... 4 | 47
cataract 4 | 26
decreased circulating insulin ... 4 | 75
decreased circulating serum al... 4 | 79
decreased circulating total pr... 4 | 41
decreased leukocyte cell numbe... 4 | 54
decreased mean corpuscular hem... 4 | 19
decreased prepulse inhibition 4 | 52
decreased rib number 4 | 59
impaired pupillary reflex 4 | 14
increased B cell number 4 | 23
increased NK cell number 4 | 19
increased circulating iron lev... 4 | 25
increased circulating sodium l... 4 | 71
increased total body fat amoun... 4 | 57
microphthalmia 4 | 15
prenatal lethality prior to he... 4 | 64
vertebral fusion 4 | 23
abnormal heart morphology 3 | 51
abnormal optic disc morphology 3 | 10
abnormal retinal blood vessel ... 3 | 18
abnormal rib morphology 3 | 28
abnormal snout morphology 3 | 18
abnormal startle reflex 3 | 14
abnormal tooth morphology 3 | 24
absent pinna reflex 3 | 21
absent vibrissae 3 | 14
decreased CD4-positive, alpha ... 3 | 19
decreased blood urea nitrogen ... 3 | 31
decreased circulating alanine ... 3 | 53
decreased circulating chloride... 3 | 32
decreased circulating iron lev... 3 | 25
decreased circulating sodium l... 3 | 18
decreased eosinophil cell numb... 3 | 41
decreased heart weight 3 | 44
decreased hematocrit 3 | 25
decreased neutrophil cell numb... 3 | 37
increased bone mineral content 3 | 92
increased circulating chloride... 3 | 43
increased circulating potassiu... 3 | 31
increased circulating triglyce... 3 | 24
increased exploration in new e... 3 | 56
increased mean corpuscular hem... 3 | 25
increased rib number 3 | 41
male infertility 3 | 62
short tibia 3 | 82
trunk curl 3 | 15

Disease

ovarian cancer 253 | 8,484
osteosarcoma 233 | 7,933
psoriasis 204 | 6,685
medulloblastoma, large-cell 174 | 6,234
glioblastoma 164 | 5,572
lung cancer 159 | 4,466
Cancer 140 | 2,346
atypical teratoid / rhabdoid tumor 135 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 105 | 3,289
malignant mesothelioma 104 | 3,162
Breast cancer 103 | 3,094
invasive ductal carcinoma 101 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 100 | 2,956
oligodendroglioma 100 | 2,849
primitive neuroectodermal tumor 100 | 3,031
non-small cell lung cancer 94 | 2,798
Carcinoma 93 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 91 | 2,988
pilocytic astrocytoma 91 | 3,086
ependymoma 89 | 2,514
pediatric high grade glioma 83 | 2,712
lung adenocarcinoma 79 | 2,713
lung carcinoma 79 | 2,844
pancreatic cancer 79 | 2,300
pituitary cancer 78 | 1,972
ulcerative colitis 76 | 2,087
interstitial cystitis 73 | 2,299
subependymal giant cell astrocytoma 69 | 2,287
astrocytoma 68 | 1,493
ductal carcinoma in situ 67 | 1,745
astrocytic glioma 63 | 2,241
group 3 medulloblastoma 62 | 2,254
group 4 medulloblastoma 62 | 1,875
sonic hedgehog group medulloblastoma 59 | 1,482
cystic fibrosis 57 | 1,665
breast carcinoma 56 | 1,614
Pick disease 55 | 1,893
adult high grade glioma 54 | 2,148
diabetes mellitus 54 | 1,663
colon cancer 52 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 52 | 1,795
tuberculosis 50 | 1,557
adrenocortical carcinoma 49 | 1,427
medulloblastoma 49 | 1,524
acute quadriplegic myopathy 47 | 1,157
primary pancreatic ductal adenocarcinoma 47 | 1,271
cutaneous lupus erythematosus 45 | 1,056
posterior fossa group B ependymoma 45 | 1,530
nasopharyngeal carcinoma 44 | 1,056
juvenile dermatomyositis 43 | 1,189
spina bifida 41 | 1,064
Intellectual disability 39 | 573
Melanoma 39 | 261
Rheumatoid Arthritis 39 | 1,160
atypical teratoid/rhabdoid tumor 39 | 1,095
posterior fossa group A ependymoma 39 | 1,511
Prostatic Neoplasms 38 | 471
gastric carcinoma 37 | 832
Multiple myeloma 35 | 1,327
primary Sjogren syndrome 35 | 789
Atopic dermatitis 34 | 944
Mammary Neoplasms 34 | 410
dermatomyositis 33 | 933
Obesity 31 | 616
Endometriosis 30 | 535
Alzheimer's disease 27 | 644
Retinitis pigmentosa 27 | 153
autosomal dominant Emery-Dreifuss muscular dystrophy 27 | 499
Duchenne muscular dystrophy 26 | 602
non primary Sjogren syndrome sicca 26 | 840
Kidney disease 25 | 396
Neurodegenerative disease 25 | 383
Blindness 24 | 84
Down syndrome 24 | 548
Hermansky-Pudlak syndrome 24 | 43
acute myeloid leukemia 24 | 780
progressive supranuclear palsy 24 | 674
Craniofacial Abnormalities 23 | 147
Microphthalmia 23 | 78
aldosterone-producing adenoma 23 | 664
esophageal adenocarcinoma 23 | 737
Colorectal Neoplasms 22 | 217
Lung Neoplasms 22 | 171
Peripheral Neuropathy 22 | 303
fibroadenoma 22 | 557
non-small cell lung carcinoma 22 | 413
Adenoma 21 | 165
Oculocutaneous albinism 21 | 27
Stomach Neoplasms 21 | 282
Amyotrophic Lateral Sclerosis 20 | 431
Fundus dystrophy 20 | 77
Hypertension 20 | 287
Schizophrenia 20 | 501
Asthma 19 | 349
gastric cancer 19 | 430
Colonic Neoplasms 18 | 126
Liver carcinoma 18 | 217
Vascular disease 18 | 281
active Crohn's disease 18 | 918
pancreatic carcinoma 18 | 567

Tissue

Digestive Tract 457 | 18,473
Endocrine System 457 | 18,512
Female tissues 456 | 18,647
Nervous System 456 | 18,561
Urinary Tract 456 | 18,444
Cardiovascular System 453 | 17,958
Skin and soft tissues 453 | 18,115
Liver and Pancreas 452 | 18,136
Male tissues 451 | 17,969
Blood and immune system 450 | 17,995
Respiratory system 449 | 17,484

Target Family

Non-IDG 240 | 11,971
Enzyme 93 | 4,146
Transcription Factor 54 | 1,400
Kinase 26 | 634
GPCR 16 | 406
Transporter 12 | 473
Ion Channel 7 | 341
Epigenetic 5 | 242
Nuclear Receptor 5 | 48
TF/Epigenetic 1 | 38

MGI Term

pigmentation phenotype 459 | 459
mortality/aging 4,850 | 4,850
homeostasis/metabolism phenoty... 4,454 | 4,454
growth/size/body region phenot... 3,915 | 3,915
cellular phenotype 3,348 | 3,348
nervous system phenotype 3,201 | 3,201
behavior/neurological phenotyp... 3,192 | 3,192
immune system phenotype 3,148 | 3,148
hematopoietic system phenotype 3,145 | 3,145
cardiovascular system phenotyp... 2,448 | 2,448
endocrine/exocrine gland pheno... 2,084 | 2,084
skeleton phenotype 2,058 | 2,058
normal phenotype 1,916 | 1,916
reproductive system phenotype 1,873 | 1,873
integument phenotype 1,748 | 1,748
embryo phenotype 1,674 | 1,674
vision/eye phenotype 1,478 | 1,478
muscle phenotype 1,385 | 1,385
digestive/alimentary phenotype 1,292 | 1,292
respiratory system phenotype 1,291 | 1,291
liver/biliary system phenotype 1,160 | 1,160
renal/urinary system phenotype 1,157 | 1,157
craniofacial phenotype 1,077 | 1,077
limbs/digits/tail phenotype 1,011 | 1,011
neoplasm 918 | 918
adipose tissue phenotype 901 | 901
hearing/vestibular/ear phenoty... 692 | 692
taste/olfaction phenotype 142 | 142
obsolete other phenotype 69 | 69

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.00063 1061.1 65
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Hermansky-Pudlak syndrome 5 protein HPS5 Tbio Non-IDG -1.13658 13.9 71
m7GpppN-mRNA hydrolase DCP2 Tbio Enzyme -1.89749 80.7 139