Development Level

Tbio 366 | 11,178
Tchem 75 | 1,885
Tdark 33 | 6,569
Tclin 32 | 612

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 54 | 979
abnormal coat-hair pigmentatio... 50 | 64
abnormal retina morphology 35 | 71
preweaning lethality, incomple... 33 | 499
enlarged heart 18 | 210
abnormal behavior 17 | 298
decreased body weight 15 | 161
decreased vertical activity 13 | 208
embryonic lethality prior to t... 13 | 278
increased lean body mass 13 | 172
abnormal embryo size 12 | 220
decreased circulating glucose ... 12 | 126
hypoactivity 12 | 132
abnormal bone structure 11 | 187
abnormal eye morphology 11 | 68
abnormal sleep behavior 11 | 70
decreased bone mineral density 11 | 126
decreased bone mineral content 10 | 151
decreased total body fat amoun... 10 | 207
embryonic lethality prior to o... 10 | 239
increased mean corpuscular vol... 10 | 92
abnormal heart morphology 9 | 162
decreased lean body mass 9 | 135
increased total body fat amoun... 9 | 134
corneal opacity 8 | 32
decreased circulating triglyce... 8 | 79
abnormal behavioral response t... 7 | 66
abnormal bone mineralization 7 | 38
abnormal cornea morphology 7 | 31
abnormal lens morphology 7 | 81
abnormal seminal vesicle morph... 7 | 114
decreased erythrocyte cell num... 7 | 62
decreased hemoglobin content 7 | 68
hyperactivity 7 | 148
increased bone mineral density 7 | 72
increased circulating alkaline... 7 | 122
increased fasted circulating g... 7 | 76
increased or absent threshold ... 7 | 101
male infertility 7 | 123
abnormal cranium morphology 6 | 36
abnormal skin morphology 6 | 50
cataract 6 | 92
decreased body length 6 | 101
decreased caudal vertebrae num... 6 | 53
decreased circulating HDL chol... 6 | 68
decreased circulating choleste... 6 | 93
decreased mean corpuscular vol... 6 | 79
decreased prepulse inhibition 6 | 82
embryonic growth retardation 6 | 106
increased hematocrit 6 | 46
increased mean corpuscular hem... 6 | 96
increased monocyte cell number 6 | 63
narrow eye opening 6 | 12
prenatal lethality prior to he... 6 | 87
small superior vagus ganglion 6 | 74
abnormal tooth morphology 5 | 24
decreased grip strength 5 | 116
decreased hematocrit 5 | 46
increased circulating choleste... 5 | 66
increased circulating triglyce... 5 | 42
increased hemoglobin content 5 | 45
increased startle reflex 5 | 112
mammalian phenotype 5 | 17
microphthalmia 5 | 26
vertebral fusion 5 | 23
abnormal gait 4 | 69
abnormal iris morphology 4 | 13
abnormal neural tube closure 4 | 46
abnormal pericardium morpholog... 4 | 26
abnormal placenta size 4 | 20
abnormal retinal blood vessel ... 4 | 26
abnormal retinal vasculature m... 4 | 27
abnormal snout morphology 4 | 23
absent pinna reflex 4 | 23
corneal vascularization 4 | 6
decreased circulating LDL chol... 4 | 38
decreased circulating chloride... 4 | 30
decreased circulating insulin ... 4 | 76
decreased circulating sodium l... 4 | 22
decreased circulating total pr... 4 | 49
decreased fasted circulating g... 4 | 65
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
decreased neutrophil cell numb... 4 | 42
decreased startle reflex 4 | 75
edema 4 | 59
female infertility 4 | 60
impaired pupillary reflex 4 | 26
increased body weight 4 | 25
increased circulating HDL chol... 4 | 80
increased circulating free fat... 4 | 20
increased circulating iron lev... 4 | 30
increased heart weight 4 | 62
increased mean corpuscular hem... 4 | 36
increased mean platelet volume 4 | 45
pale yolk sac 4 | 25
short tibia 4 | 97
anophthalmia 3 | 33
increased bone mineral content 3 | 108
increased circulating sodium l... 3 | 71

Disease

Carcinoma 344 | 11,192
ovarian cancer 271 | 8,297
osteosarcoma 249 | 7,766
psoriasis 211 | 6,514
medulloblastoma, large-cell 189 | 6,086
glioblastoma 178 | 5,635
lung cancer 173 | 4,607
atypical teratoid / rhabdoid tumor 166 | 4,971
ependymoma 155 | 4,559
Cancer 145 | 2,388
group 3 medulloblastoma 133 | 4,002
Breast cancer 131 | 3,469
malignant mesothelioma 119 | 3,135
Autosomal recessive predisposition 116 | 1,407
primitive neuroectodermal tumor 109 | 2,957
intraductal papillary-mucinous neoplasm (IPMN) 107 | 3,204
oligodendroglioma 106 | 2,768
Kidney cancer 105 | 2,548
invasive ductal carcinoma 105 | 2,867
adult high grade glioma 102 | 3,701
intraductal papillary-mucinous adenoma (IPMA) 102 | 2,872
non-small cell lung cancer 98 | 2,799
Astrocytoma, Pilocytic 95 | 3,006
intraductal papillary-mucinous carcinoma (IPMC) 95 | 2,902
astrocytic glioma 91 | 2,530
Intellectual disability 89 | 998
pancreatic cancer 85 | 2,322
lung adenocarcinoma 82 | 2,627
lung carcinoma 81 | 2,755
pituitary cancer 81 | 1,915
interstitial cystitis 76 | 2,237
Dull intelligence 75 | 634
Low intelligence 75 | 634
Mental Retardation 75 | 634
Mental deficiency 75 | 634
Poor school performance 75 | 634
subependymal giant cell astrocytoma 74 | 2,230
ulcerative colitis 71 | 1,765
ductal carcinoma in situ 69 | 1,686
pancreatic ductal adenocarcinoma liver metastasis 66 | 1,911
tuberculosis 65 | 1,963
Melanoma 63 | 689
group 4 medulloblastoma 62 | 1,806
Pick disease 61 | 1,856
diabetes mellitus 61 | 1,683
Schizophrenia 60 | 1,136
breast carcinoma 60 | 1,589
cystic fibrosis 59 | 1,629
Epilepsy 56 | 775
colon cancer 56 | 1,428
Obesity 52 | 655
Seizures 51 | 584
Short stature 51 | 514
astrocytoma 51 | 1,113
Muscle hypotonia 50 | 562
acute quadriplegic myopathy 49 | 1,133
Cataract 48 | 290
Nystagmus 48 | 309
Sensorineural Hearing Loss (disorder) 48 | 281
adrenocortical carcinoma 48 | 1,385
Cognitive delay 47 | 596
Global developmental delay 47 | 596
Mental and motor retardation 47 | 596
Lens Opacities 46 | 227
cutaneous lupus erythematosus 46 | 1,016
Strabismus 45 | 265
juvenile dermatomyositis 44 | 1,147
nasopharyngeal carcinoma 44 | 1,024
spina bifida 44 | 1,053
Skin cancer 42 | 451
Multiple myeloma 41 | 1,296
Rheumatoid arthritis 41 | 1,156
pediatric high grade glioma 41 | 1,035
Broad flat nasal bridge 40 | 232
Nasal bridge wide 40 | 232
primary pancreatic ductal adenocarcinoma 38 | 1,071
Small head 37 | 366
Breast Neoplasms 36 | 423
Glaucoma 36 | 232
Mammary Neoplasms 36 | 403
Optic Atrophy 36 | 239
Photodysphoria 36 | 117
Photophobia 36 | 117
non primary Sjogren syndrome sicca 36 | 861
Atopic dermatitis 35 | 915
Prostatic Neoplasms 35 | 472
Low Vision 34 | 167
Visual Impairment 34 | 167
Depressive disorder 33 | 401
gastric carcinoma 33 | 781
primary Sjogren syndrome 33 | 710
Congenital hypoplasia of penis 32 | 168
Hypoplastic mandible condyle 32 | 273
Liver cancer 32 | 589
Mandibular hypoplasia 32 | 273
Micrognathism 32 | 273
dermatomyositis 32 | 941
Anteverted nostril 31 | 186
Bipolar Disorder 31 | 646
Endometriosis 31 | 521

Tissue

Endocrine System 494 | 18,159
Skin and soft tissues 485 | 17,230
Female tissues 483 | 17,400
Digestive Tract 480 | 17,369
Male tissues 479 | 17,142
Blood and immune system 473 | 16,909
Nervous System 472 | 16,725
Liver and Pancreas 467 | 16,750
Urinary Tract 465 | 16,678
Respiratory system 455 | 16,393
Cardiovascular System 436 | 15,192

Target Family

Non-IDG 258 | 12,091
Enzyme 112 | 4,145
Transcription Factor 57 | 1,400
Kinase 29 | 634
GPCR 16 | 408
Transporter 14 | 473
Ion Channel 9 | 344
Epigenetic 6 | 242
Nuclear Receptor 4 | 48
TF/Epigenetic 1 | 38

MGI Phenotype

pigmentation phenotype 506 | 506
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Protein RCC2 RCC2 Tbio Non-IDG -1.49831 31.4 148
Prominin-2 PROM2 Tbio Non-IDG -1.12562 11.0 199
Keratin, type I cytoskeletal 17 KRT17 Tbio Non-IDG -2.43909 265.8 711
C-Jun-amino-terminal kinase-interacting protein 4 SPAG9 Tbio Enzyme -2.45490 258.6 149
Alkaline ceramidase 1 ACER1 Tbio Enzyme -0.89946 7.07 114
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
P protein OCA2 Tbio Non-IDG -2.47946 286.8 125
Transcription factor E3 TFE3 Tbio Transcription Factor -2.43611 297.2 314
Ribosome biogenesis protein WDR12 WDR12 Tbio Non-IDG -1.28968 20.5 125