Development Level

Tbio 1,322 | 11,178
Tchem 404 | 1,885
Tclin 157 | 612
Tdark 116 | 6,569

Collection

Ion Channel: IDG Consortium (T... 15 | 99
Kinase: IDG Consortium (Target... 11 | 125
GPCR: IDG Consortium (Targets) 9 | 126
GPCR: IDG Consortium (Complete... 8 | 25
Kinase: IDG Consortium (Comple... 5 | 37

IMPC Phenotype

preweaning lethality, complete... 137 | 979
preweaning lethality, incomple... 72 | 499
embryonic lethality prior to t... 47 | 278
abnormal behavior 46 | 298
decreased vertical activity 39 | 208
abnormal bone structure 33 | 187
increased total body fat amoun... 32 | 134
abnormal embryo size 31 | 220
decreased total body fat amoun... 30 | 207
increased lean body mass 30 | 172
embryonic lethality prior to o... 29 | 239
decreased body weight 26 | 161
decreased bone mineral content 26 | 151
enlarged heart 26 | 210
abnormal heart morphology 22 | 162
decreased lean body mass 22 | 135
hypoactivity 21 | 132
abnormal seminal vesicle morph... 20 | 114
decreased circulating glucose ... 20 | 126
increased startle reflex 20 | 112
hyperactivity 19 | 148
decreased bone mineral density 18 | 126
decreased circulating choleste... 17 | 93
increased circulating alkaline... 17 | 122
prenatal lethality prior to he... 17 | 87
abnormal gait 16 | 69
impaired glucose tolerance 16 | 75
decreased lymphocyte cell numb... 15 | 83
decreased grip strength 14 | 116
increased bone mineral content 14 | 108
increased mean corpuscular hem... 14 | 96
abnormal eye morphology 13 | 68
abnormal retina morphology 13 | 71
decreased body length 13 | 101
decreased circulating insulin ... 13 | 76
decreased prepulse inhibition 13 | 82
increased circulating HDL chol... 13 | 80
increased circulating choleste... 13 | 66
decreased circulating HDL chol... 12 | 68
improved glucose tolerance 12 | 79
increased mean corpuscular vol... 12 | 92
increased monocyte cell number 12 | 63
increased neutrophil cell numb... 12 | 46
abnormal lens morphology 11 | 81
decreased circulating iron lev... 11 | 32
decreased mean corpuscular vol... 11 | 79
edema 11 | 59
embryonic growth retardation 11 | 106
increased heart weight 11 | 62
male infertility 11 | 123
abnormal kidney morphology 10 | 65
abnormal sleep behavior 10 | 70
cataract 10 | 92
decreased erythrocyte cell num... 10 | 62
decreased hemoglobin content 10 | 68
increased circulating sodium l... 10 | 71
increased circulating triglyce... 10 | 42
increased or absent threshold ... 10 | 101
short tibia 10 | 97
abnormal skin morphology 9 | 50
decreased circulating alkaline... 9 | 46
decreased circulating triglyce... 9 | 79
increased circulating chloride... 9 | 41
increased circulating iron lev... 9 | 30
increased fasted circulating g... 9 | 76
increased hemoglobin content 9 | 45
limb grasping 9 | 41
thrombocytopenia 9 | 56
tremors 9 | 39
abnormal epididymis morphology 8 | 42
decreased fasted circulating g... 8 | 65
decreased neutrophil cell numb... 8 | 42
decreased startle reflex 8 | 75
female infertility 8 | 60
increased blood urea nitrogen ... 8 | 48
increased bone mineral density 8 | 72
increased circulating serum al... 8 | 22
microphthalmia 8 | 26
abnormal bone mineralization 7 | 38
abnormal retinal blood vessel ... 7 | 26
abnormal retinal vasculature m... 7 | 27
abnormal testis morphology 7 | 43
anophthalmia 7 | 33
corneal opacity 7 | 32
decreased circulating amylase ... 7 | 28
decreased circulating serum al... 7 | 82
decreased heart weight 7 | 27
decreased hematocrit 7 | 46
decreased leukocyte cell numbe... 7 | 73
enlarged lymph nodes 7 | 37
increased body weight 7 | 25
increased circulating amylase ... 7 | 25
increased circulating creatini... 7 | 38
increased circulating glucose ... 7 | 24
increased circulating total pr... 7 | 28
small superior vagus ganglion 7 | 74
abnormal coat-hair pigmentatio... 6 | 64
decreased circulating total pr... 6 | 49
decreased spleen weight 6 | 10
pallor 6 | 34

Disease

Carcinoma 1,329 | 11,192
ovarian cancer 1,002 | 8,297
osteosarcoma 907 | 7,766
psoriasis 821 | 6,514
medulloblastoma, large-cell 792 | 6,086
glioblastoma 784 | 5,635
atypical teratoid / rhabdoid tumor 680 | 4,971
lung cancer 652 | 4,607
Cancer 622 | 2,388
ependymoma 611 | 4,559
Breast cancer 524 | 3,469
group 3 medulloblastoma 512 | 4,002
adult high grade glioma 497 | 3,701
malignant mesothelioma 490 | 3,135
Astrocytoma, Pilocytic 448 | 3,006
invasive ductal carcinoma 432 | 2,867
oligodendroglioma 426 | 2,768
non-small cell lung cancer 425 | 2,799
lung carcinoma 412 | 2,755
Kidney cancer 410 | 2,548
primitive neuroectodermal tumor 407 | 2,957
lung adenocarcinoma 405 | 2,627
intraductal papillary-mucinous neoplasm (IPMN) 397 | 3,204
intraductal papillary-mucinous adenoma (IPMA) 392 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 384 | 2,902
pancreatic cancer 363 | 2,322
astrocytic glioma 352 | 2,530
interstitial cystitis 344 | 2,237
subependymal giant cell astrocytoma 314 | 2,230
pituitary cancer 307 | 1,915
breast carcinoma 280 | 1,589
cystic fibrosis 275 | 1,629
ductal carcinoma in situ 268 | 1,686
ulcerative colitis 268 | 1,765
Schizophrenia 261 | 1,136
tuberculosis 261 | 1,963
diabetes mellitus 250 | 1,683
Pick disease 239 | 1,856
group 4 medulloblastoma 237 | 1,806
adrenocortical carcinoma 229 | 1,385
colon cancer 221 | 1,428
Autosomal recessive predisposition 214 | 1,407
pancreatic ductal adenocarcinoma liver metastasis 199 | 1,911
Rheumatoid arthritis 196 | 1,156
primary pancreatic ductal adenocarcinoma 184 | 1,071
astrocytoma 181 | 1,113
Intellectual disability 176 | 998
juvenile dermatomyositis 167 | 1,147
cutaneous lupus erythematosus 163 | 1,016
Epilepsy 160 | 775
acute quadriplegic myopathy 156 | 1,133
pediatric high grade glioma 153 | 1,035
Bipolar Disorder 150 | 646
spina bifida 150 | 1,053
Obesity 146 | 655
dermatomyositis 143 | 941
Alzheimer's disease 141 | 640
Multiple myeloma 141 | 1,296
Liver Cirrhosis, Experimental 139 | 733
Melanoma 137 | 689
Seizures 132 | 584
gastric carcinoma 132 | 781
Dull intelligence 130 | 634
Low intelligence 130 | 634
Mental Retardation 130 | 634
Mental deficiency 130 | 634
Poor school performance 130 | 634
nasopharyngeal carcinoma 130 | 1,024
Breast Neoplasms 129 | 423
Atopic dermatitis 128 | 915
Mammary Neoplasms 127 | 403
Short stature 126 | 514
Liver cancer 119 | 589
active Crohn's disease 118 | 882
Endometriosis 117 | 521
Cognitive delay 116 | 596
Global developmental delay 116 | 596
Mental and motor retardation 116 | 596
Prostatic Neoplasms 116 | 472
medulloblastoma 114 | 702
Kidney disease 109 | 411
Depressive disorder 108 | 401
Duchenne muscular dystrophy 106 | 587
Muscle hypotonia 106 | 562
esophageal adenocarcinoma 106 | 696
Down syndrome 105 | 480
Waldenstrons macroglobulinemia 104 | 742
active ulcerative colitis 104 | 736
non primary Sjogren syndrome sicca 103 | 861
autosomal dominant Emery-Dreifuss muscular dystrophy 102 | 492
primary Sjogren syndrome 101 | 710
Hypertension 100 | 372
acute myeloid leukemia 100 | 760
aldosterone-producing adenoma 97 | 646
Skin cancer 95 | 451
Parkinson's disease 94 | 378
Autistic Disorder 92 | 358
Major Depressive Disorder 91 | 293
Multiple Sclerosis 86 | 527
fibroadenoma 83 | 538

Tissue

Endocrine System 1,943 | 18,159
Digestive Tract 1,904 | 17,369
Skin and soft tissues 1,883 | 17,230
Female tissues 1,878 | 17,400
Male tissues 1,860 | 17,142
Blood and immune system 1,837 | 16,909
Nervous System 1,831 | 16,725
Urinary Tract 1,831 | 16,678
Liver and Pancreas 1,827 | 16,750
Respiratory system 1,784 | 16,393
Cardiovascular System 1,680 | 15,192

Target Family

Non-IDG 943 | 12,091
Enzyme 380 | 4,145
Transcription Factor 277 | 1,400
Kinase 150 | 634
GPCR 73 | 408
Ion Channel 61 | 344
Epigenetic 51 | 242
Transporter 29 | 473
Nuclear Receptor 23 | 48
TF/Epigenetic 11 | 38
oGPCR 1 | 421

MGI Phenotype

normal phenotype 1,999 | 1,999
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Protein SOX-15 SOX15 Tbio Transcription Factor -1.31464 23.3 166
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 GCNT4 Tdark Enzyme -1.56850 33.7 45
Protein atonal homolog 7 ATOH7 Tbio Transcription Factor -3.08645 1060.6 178
Zinc finger protein 423 ZNF423 Tbio Transcription Factor -1.62303 45.3 77
Secreted frizzled-related protein 5 SFRP5 Tbio Non-IDG -1.81796 74.9 180
Neuronatin NNAT Tbio Non-IDG -1.98217 101.3 38
Serine/threonine-protein kinase N1 PKN1 Tchem Kinase -2.03368 117.6 153