Development Level

Tbio 569 | 10,625
Tchem 252 | 1,890
Tclin 85 | 602
Tdark 12 | 7,003

Collection

Eligible Kinase Proteins 4 | 134
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, complete... 46 | 633
embryonic lethality prior to t... 20 | 187
decreased body weight 18 | 174
preweaning lethality, incomple... 17 | 260
decreased bone mineral content 15 | 157
decreased lean body mass 15 | 195
decreased bone mineral density 12 | 126
decreased circulating triglyce... 12 | 83
decreased total body fat amoun... 12 | 186
embryonic lethality prior to o... 12 | 148
abnormal behavior 11 | 226
abnormal retina morphology 11 | 100
increased circulating alkaline... 11 | 119
decreased body length 10 | 108
abnormal bone mineralization 9 | 55
abnormal bone structure 9 | 131
increased mean corpuscular hem... 9 | 93
decreased circulating HDL chol... 8 | 77
decreased circulating alkaline... 8 | 41
decreased circulating choleste... 8 | 85
decreased circulating glucose ... 8 | 121
decreased hemoglobin content 8 | 53
increased circulating choleste... 8 | 53
increased lean body mass 8 | 107
increased mean corpuscular vol... 8 | 91
increased or absent threshold ... 8 | 128
thrombocytopenia 8 | 46
abnormal embryo size 7 | 112
abnormal eye morphology 7 | 38
decreased circulating alanine ... 7 | 53
decreased grip strength 7 | 123
enlarged heart 7 | 111
abnormal lens morphology 6 | 73
abnormal retinal pigmentation 6 | 61
cataract 6 | 26
decreased circulating free fat... 6 | 39
decreased leukocyte cell numbe... 6 | 54
hypoactivity 6 | 89
increased bone mineral content 6 | 92
increased circulating HDL chol... 6 | 63
increased grip strength 6 | 83
increased heart weight 6 | 37
short tibia 6 | 82
abnormal coat/hair pigmentatio... 5 | 54
abnormal sleep behavior 5 | 63
decreased T cell number 5 | 31
decreased circulating LDL chol... 5 | 37
decreased circulating fructosa... 5 | 31
decreased circulating insulin ... 5 | 75
decreased circulating serum al... 5 | 79
decreased erythrocyte cell num... 5 | 43
decreased lactate dehydrogenas... 5 | 14
decreased lumbar vertebrae num... 5 | 62
decreased prepulse inhibition 5 | 52
increased circulating calcium ... 5 | 32
increased circulating glucose ... 5 | 16
increased circulating triglyce... 5 | 24
increased hemoglobin content 5 | 45
increased total body fat amoun... 5 | 57
abnormal heart morphology 4 | 51
abnormal neural tube closure 4 | 37
abnormal response to tactile s... 4 | 16
abnormal spleen morphology 4 | 36
decreased blood urea nitrogen ... 4 | 31
decreased circulating creatini... 4 | 31
decreased circulating total pr... 4 | 41
decreased eosinophil cell numb... 4 | 41
decreased heart weight 4 | 44
decreased hematocrit 4 | 25
decreased mean corpuscular vol... 4 | 50
decreased neutrophil cell numb... 4 | 37
improved glucose tolerance 4 | 56
increased body weight 4 | 42
increased bone mineral density 4 | 52
increased exploration in new e... 4 | 56
increased leukocyte cell numbe... 4 | 37
increased mean corpuscular hem... 4 | 25
increased sacral vertebrae num... 4 | 62
male infertility 4 | 62
small testis 4 | 37
abnormal coping response 3 | 12
abnormal gait 3 | 51
abnormal startle reflex 3 | 14
abnormal testis morphology 3 | 30
abnormal tooth morphology 3 | 24
decreased circulating aspartat... 3 | 27
decreased fasted circulating g... 3 | 49
decreased rib number 3 | 59
female infertility 3 | 34
hydrops fetalis 3 | 22
impaired glucose tolerance 3 | 52
increased circulating iron lev... 3 | 25
increased circulating potassiu... 3 | 31
increased circulating serum al... 3 | 25
increased circulating sodium l... 3 | 71
increased circulating total pr... 3 | 20
increased startle reflex 3 | 38
persistence of hyaloid vascula... 3 | 22
prenatal lethality prior to he... 3 | 64
vertebral fusion 3 | 23

Disease

ovarian cancer 557 | 8,484
Cancer 541 | 2,346
osteosarcoma 512 | 7,933
psoriasis 459 | 6,685
glioblastoma 400 | 5,572
lung cancer 391 | 4,466
medulloblastoma, large-cell 376 | 6,234
Breast cancer 277 | 3,094
malignant mesothelioma 263 | 3,162
atypical teratoid / rhabdoid tumor 252 | 4,369
non-small cell lung cancer 252 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 242 | 3,289
invasive ductal carcinoma 242 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 240 | 2,988
lung adenocarcinoma 232 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 228 | 2,956
lung carcinoma 225 | 2,844
pancreatic cancer 223 | 2,300
pediatric high grade glioma 206 | 2,712
pilocytic astrocytoma 206 | 3,086
ulcerative colitis 204 | 2,087
primitive neuroectodermal tumor 201 | 3,031
Carcinoma 190 | 2,147
interstitial cystitis 185 | 2,299
pituitary cancer 173 | 1,972
oligodendroglioma 168 | 2,849
subependymal giant cell astrocytoma 166 | 2,287
tuberculosis 162 | 1,557
cystic fibrosis 152 | 1,665
colon cancer 150 | 1,475
ductal carcinoma in situ 150 | 1,745
diabetes mellitus 149 | 1,663
breast carcinoma 148 | 1,614
group 3 medulloblastoma 145 | 2,254
ependymoma 143 | 2,514
group 4 medulloblastoma 133 | 1,875
adrenocortical carcinoma 132 | 1,427
astrocytoma 129 | 1,493
primary pancreatic ductal adenocarcinoma 126 | 1,271
posterior fossa group A ependymoma 122 | 1,511
Rheumatoid Arthritis 121 | 1,160
Mammary Neoplasms 119 | 410
Prostatic Neoplasms 117 | 471
adult high grade glioma 113 | 2,148
cutaneous lupus erythematosus 111 | 1,056
juvenile dermatomyositis 109 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 109 | 1,795
acute quadriplegic myopathy 108 | 1,157
Multiple myeloma 106 | 1,327
nasopharyngeal carcinoma 104 | 1,056
astrocytic glioma 100 | 2,241
dermatomyositis 98 | 933
Pick disease 96 | 1,893
sonic hedgehog group medulloblastoma 91 | 1,482
Endometriosis 90 | 535
medulloblastoma 90 | 1,524
Lung Neoplasms 85 | 171
primary Sjogren syndrome 84 | 789
spina bifida 81 | 1,064
Kidney disease 80 | 396
Multiple Sclerosis 80 | 498
gastric carcinoma 80 | 832
Obesity 79 | 616
esophageal adenocarcinoma 77 | 737
Adenoma 76 | 165
Stomach Neoplasms 75 | 282
atypical teratoid/rhabdoid tumor 75 | 1,095
Arthritis 73 | 248
Atopic dermatitis 73 | 944
Asthma 71 | 349
Down syndrome 70 | 548
Waldenstrons macroglobulinemia 70 | 765
non-small cell lung carcinoma 70 | 413
Alzheimer's disease 69 | 644
active Crohn's disease 69 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 68 | 499
Vascular disease 67 | 281
Liver carcinoma 66 | 217
acute myeloid leukemia 65 | 780
posterior fossa group B ependymoma 65 | 1,530
Colorectal Neoplasms 64 | 217
Duchenne muscular dystrophy 62 | 602
Heart disease 60 | 279
Peripheral Neuropathy 58 | 303
IGA Glomerulonephritis 57 | 454
Liver disease 56 | 219
Atherosclerosis 55 | 275
Melanoma 54 | 261
Hypersensitivity reaction type II disease 53 | 235
aldosterone-producing adenoma 53 | 664
pancreatic carcinoma 53 | 567
Neoplasm Metastasis 51 | 138
Hypertensive disease 50 | 193
Lung disease 50 | 132
hepatocellular carcinoma 50 | 532
Amyotrophic Lateral Sclerosis 49 | 431
Colonic Neoplasms 49 | 126
Schizophrenia 49 | 501
mucosa-associated lymphoid tissue lymphoma 49 | 480
Adenocarcinoma 46 | 115

Tissue

Endocrine System 910 | 18,512
Female tissues 909 | 18,647
Nervous System 909 | 18,561
Urinary Tract 909 | 18,444
Digestive Tract 908 | 18,473
Liver and Pancreas 904 | 18,136
Blood and immune system 901 | 17,995
Male tissues 901 | 17,969
Cardiovascular System 900 | 17,958
Skin and soft tissues 898 | 18,115
Respiratory system 894 | 17,484

Target Family

Non-IDG 426 | 11,971
Enzyme 197 | 4,146
Transcription Factor 109 | 1,400
Kinase 97 | 634
Epigenetic 29 | 242
GPCR 26 | 406
Nuclear Receptor 12 | 48
Transporter 12 | 473
TF/Epigenetic 6 | 38
Ion Channel 4 | 341

MGI Term

neoplasm 918 | 918
mortality/aging 4,850 | 4,850
homeostasis/metabolism phenoty... 4,454 | 4,454
growth/size/body region phenot... 3,915 | 3,915
cellular phenotype 3,348 | 3,348
nervous system phenotype 3,201 | 3,201
behavior/neurological phenotyp... 3,192 | 3,192
immune system phenotype 3,148 | 3,148
hematopoietic system phenotype 3,145 | 3,145
cardiovascular system phenotyp... 2,448 | 2,448
endocrine/exocrine gland pheno... 2,084 | 2,084
skeleton phenotype 2,058 | 2,058
normal phenotype 1,916 | 1,916
reproductive system phenotype 1,873 | 1,873
integument phenotype 1,748 | 1,748
embryo phenotype 1,674 | 1,674
vision/eye phenotype 1,478 | 1,478
muscle phenotype 1,385 | 1,385
digestive/alimentary phenotype 1,292 | 1,292
respiratory system phenotype 1,291 | 1,291
liver/biliary system phenotype 1,160 | 1,160
renal/urinary system phenotype 1,157 | 1,157
craniofacial phenotype 1,077 | 1,077
limbs/digits/tail phenotype 1,011 | 1,011
adipose tissue phenotype 901 | 901
hearing/vestibular/ear phenoty... 692 | 692
pigmentation phenotype 459 | 459
taste/olfaction phenotype 142 | 142
obsolete other phenotype 69 | 69

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Programmed cell death protein 4 PDCD4 Tchem Non-IDG -2.40380 284.9 546
Class A basic helix-loop-helix protein 15 BHLHA15 Tbio Transcription Factor -1.24086 19.1 70