Development Level

Tbio 3,736 | 11,445
Tchem 738 | 1,598
Tclin 307 | 613
Tdark 237 | 6,588

Collection

RFA-RM-18-021 43 | 328
Kinase: IDG Consortium (Target... 22 | 125
Ion Channel: IDG Consortium (T... 16 | 99
Kinase: IDG Consortium (Comple... 13 | 37
GPCR: IDG Consortium (Complete... 5 | 25
GPCR: IDG Consortium (Targets) 5 | 126

IMPC Phenotype

preweaning lethality, complete... 781 | 979
preweaning lethality, incomple... 319 | 499
embryonic lethality prior to t... 254 | 278
embryonic lethality prior to o... 214 | 239
abnormal embryo size 195 | 220
abnormal behavior 115 | 298
embryonic growth retardation 95 | 106
enlarged heart 95 | 210
decreased total body fat amoun... 81 | 207
decreased vertical activity 80 | 208
prenatal lethality prior to he... 80 | 87
abnormal bone structure 78 | 187
abnormal heart morphology 76 | 162
decreased body weight 69 | 161
increased lean body mass 66 | 172
decreased bone mineral content 64 | 151
increased total body fat amoun... 63 | 134
hypoactivity 61 | 132
decreased lean body mass 59 | 135
increased startle reflex 59 | 112
abnormal seminal vesicle morph... 54 | 114
edema 52 | 59
decreased circulating glucose ... 50 | 126
cataract 49 | 92
hyperactivity 48 | 148
increased circulating alkaline... 48 | 122
impaired glucose tolerance 46 | 75
decreased bone mineral density 45 | 126
abnormal lens morphology 44 | 81
decreased grip strength 44 | 116
increased bone mineral content 44 | 108
decreased prepulse inhibition 43 | 82
abnormal neural tube closure 41 | 46
abnormal eye morphology 40 | 68
decreased circulating choleste... 39 | 93
decreased mean corpuscular vol... 38 | 79
male infertility 38 | 123
small superior vagus ganglion 38 | 74
decreased body length 37 | 101
decreased lymphocyte cell numb... 37 | 83
increased mean corpuscular hem... 37 | 96
short tibia 37 | 97
abnormal retina morphology 36 | 71
increased mean corpuscular vol... 36 | 92
decreased fasted circulating g... 35 | 65
abnormal gait 33 | 69
decreased circulating serum al... 33 | 82
decreased circulating triglyce... 33 | 79
improved glucose tolerance 33 | 79
increased fasted circulating g... 33 | 76
increased circulating HDL chol... 32 | 80
increased or absent threshold ... 32 | 101
abnormal craniofacial morpholo... 31 | 33
pallor 31 | 34
abnormal kidney morphology 30 | 65
anophthalmia 30 | 33
increased circulating choleste... 30 | 66
abnormal embryo turning 29 | 31
decreased leukocyte cell numbe... 29 | 73
increased bone mineral density 29 | 72
decreased circulating HDL chol... 28 | 68
decreased circulating insulin ... 28 | 76
increased circulating sodium l... 28 | 71
thrombocytopenia 28 | 56
abnormal coat-hair pigmentatio... 27 | 64
decreased blood urea nitrogen ... 27 | 51
decreased circulating alkaline... 27 | 46
decreased startle reflex 27 | 75
small testis 27 | 58
decreased hemoglobin content 26 | 68
increased heart weight 26 | 62
prenatal lethality 26 | 28
decreased mean corpuscular hem... 25 | 50
increased leukocyte cell numbe... 25 | 47
abnormal pericardium morpholog... 24 | 26
abnormal testis morphology 24 | 43
hydrometra 24 | 53
increased circulating chloride... 24 | 41
increased monocyte cell number 24 | 63
increased neutrophil cell numb... 24 | 46
decreased caudal vertebrae num... 23 | 53
decreased circulating alanine ... 23 | 47
decreased circulating total pr... 23 | 49
hemorrhage 23 | 23
increased circulating triglyce... 23 | 42
tremors 23 | 39
decreased erythrocyte cell num... 22 | 62
increased grip strength 22 | 41
limb grasping 22 | 41
pale yolk sac 22 | 25
abnormal skin morphology 21 | 50
enlarged lymph nodes 21 | 37
increased blood urea nitrogen ... 21 | 48
abnormal cranium morphology 20 | 36
female infertility 20 | 60
abnormal placenta size 19 | 20
corneal opacity 19 | 32
decreased circulating creatini... 19 | 39
increased mean platelet volume 19 | 45
syndactyly 19 | 23

Disease

Carcinoma 3,496 | 11,493
ovarian cancer 2,873 | 8,520
osteosarcoma 2,536 | 7,950
psoriasis 2,167 | 6,694
medulloblastoma, large-cell 2,034 | 6,241
glioblastoma 1,985 | 5,792
lung cancer 1,817 | 4,740
atypical teratoid / rhabdoid tumor 1,699 | 5,112
ependymoma 1,492 | 4,679
Cancer 1,458 | 2,499
group 3 medulloblastoma 1,397 | 4,104
Breast cancer 1,364 | 3,578
malignant mesothelioma 1,247 | 3,232
adult high grade glioma 1,230 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 1,118 | 3,291
non-small cell lung cancer 1,066 | 2,890
invasive ductal carcinoma 1,065 | 2,951
primitive neuroectodermal tumor 1,031 | 3,035
Kidney cancer 1,020 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 1,019 | 2,989
Astrocytoma, Pilocytic 1,009 | 3,081
oligodendroglioma 996 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 995 | 2,955
lung adenocarcinoma 985 | 2,716
pancreatic cancer 939 | 2,398
lung carcinoma 930 | 2,843
astrocytic glioma 872 | 2,597
Autosomal recessive predisposition 810 | 1,442
subependymal giant cell astrocytoma 789 | 2,287
interstitial cystitis 768 | 2,312
tuberculosis 711 | 2,010
pituitary cancer 683 | 1,972
Pick disease 681 | 1,894
ulcerative colitis 654 | 1,819
breast carcinoma 653 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 642 | 1,962
diabetes mellitus 641 | 1,728
ductal carcinoma in situ 633 | 1,745
colon cancer 619 | 1,478
cystic fibrosis 615 | 1,696
group 4 medulloblastoma 605 | 1,855
Intellectual disability 578 | 1,016
Schizophrenia 576 | 1,160
adrenocortical carcinoma 541 | 1,428
Multiple myeloma 508 | 1,332
acute quadriplegic myopathy 484 | 1,158
Rheumatoid arthritis 479 | 1,191
juvenile dermatomyositis 472 | 1,187
astrocytoma 463 | 1,146
Epilepsy 460 | 792
primary pancreatic ductal adenocarcinoma 452 | 1,109
dermatomyositis 415 | 966
Dull intelligence 411 | 645
Low intelligence 411 | 645
Mental Retardation 411 | 645
Mental deficiency 411 | 645
Poor school performance 411 | 645
pediatric high grade glioma 396 | 1,064
Seizures 395 | 596
Cognitive delay 391 | 608
Global developmental delay 391 | 608
Mental and motor retardation 391 | 608
spina bifida 370 | 1,074
Short stature 369 | 531
Muscle hypotonia 363 | 571
cutaneous lupus erythematosus 363 | 1,057
nasopharyngeal carcinoma 359 | 1,058
Atopic dermatitis 345 | 952
Obesity 339 | 678
Waldenstrons macroglobulinemia 333 | 765
Bipolar Disorder 329 | 666
Alzheimer's disease 313 | 658
gastric carcinoma 308 | 807
Liver Cirrhosis, Experimental 297 | 769
Melanoma 293 | 711
active Crohn's disease 289 | 922
Liver cancer 287 | 604
Breast Neoplasms 285 | 445
esophageal adenocarcinoma 275 | 737
acute myeloid leukemia 274 | 783
Mammary Neoplasms 273 | 425
non primary Sjogren syndrome sicca 263 | 891
Prostatic Neoplasms 262 | 495
medulloblastoma 262 | 720
aldosterone-producing adenoma 258 | 665
Small head 257 | 374
primary Sjogren syndrome 256 | 735
active ulcerative colitis 255 | 764
Kidney disease 252 | 430
Duchenne muscular dystrophy 245 | 601
Failure to gain weight 244 | 365
Pediatric failure to thrive 244 | 365
Down syndrome 243 | 499
progressive supranuclear palsy 239 | 676
autosomal dominant Emery-Dreifuss muscular dystrophy 236 | 510
Multiple Sclerosis 233 | 540
Hypertension 230 | 396
Depressive disorder 225 | 409
Anemia 223 | 365
Neurodegenerative disease 223 | 414

Tissue

Endocrine System 4,906 | 18,159
Digestive Tract 4,848 | 17,369
Skin and soft tissues 4,813 | 17,230
Female tissues 4,812 | 17,400
Male tissues 4,782 | 17,142
Blood and immune system 4,749 | 16,909
Nervous System 4,746 | 16,725
Urinary Tract 4,735 | 16,678
Liver and Pancreas 4,727 | 16,750
Respiratory system 4,656 | 16,393
Cardiovascular System 4,445 | 15,192

Target Family

Non-IDG 2,492 | 12,091
Enzyme 1,155 | 4,145
Transcription Factor 578 | 1,400
Kinase 284 | 634
Transporter 127 | 473
Epigenetic 122 | 242
Ion Channel 104 | 344
GPCR 100 | 408
Nuclear Receptor 37 | 48
TF/Epigenetic 19 | 38

MGI Phenotype

mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
Cryptic protein CFC1 Tbio Non-IDG -1.89131 76.4 159
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Carbonic anhydrase 12 CA12 Tclin Enzyme -2.28368 173.2 309
Protein timeless homolog TIMELESS Tbio Non-IDG -2.76871 578.0 138
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453