Development Level

Tbio 3,406 | 10,625
Tchem 870 | 1,890
Tclin 296 | 602
Tdark 278 | 7,003

Collection

Eligible Kinase Proteins 27 | 134
Eligible Ion Channel Proteins 17 | 117
Eligible non-olfactory GPCR Proteins 5 | 143

IMPC Term

preweaning lethality, complete... 622 | 633
preweaning lethality, incomple... 254 | 260
embryonic lethality prior to t... 182 | 187
embryonic lethality prior to o... 144 | 148
abnormal embryo size 106 | 112
decreased lean body mass 93 | 195
abnormal behavior 90 | 226
decreased bone mineral content 74 | 157
decreased total body fat amoun... 73 | 186
decreased body weight 69 | 174
prenatal lethality prior to he... 63 | 64
enlarged heart 58 | 111
decreased grip strength 56 | 123
abnormal retina morphology 55 | 100
abnormal bone structure 54 | 131
decreased bone mineral density 54 | 126
increased circulating alkaline... 49 | 119
increased or absent threshold ... 49 | 128
increased grip strength 46 | 83
decreased body length 45 | 108
decreased circulating glucose ... 44 | 121
increased bone mineral content 39 | 92
increased lean body mass 39 | 107
hypoactivity 38 | 89
abnormal lens morphology 37 | 73
decreased circulating choleste... 37 | 85
hyperactivity 37 | 108
increased mean corpuscular hem... 36 | 93
abnormal neural tube closure 35 | 37
decreased circulating HDL chol... 35 | 77
increased mean corpuscular vol... 35 | 91
short tibia 34 | 82
decreased circulating triglyce... 31 | 83
impaired glucose tolerance 31 | 52
increased total body fat amoun... 31 | 57
decreased circulating serum al... 30 | 79
increased fasted circulating g... 30 | 68
decreased mean corpuscular vol... 29 | 50
increased circulating HDL chol... 29 | 63
increased circulating sodium l... 29 | 71
abnormal retinal pigmentation 28 | 61
decreased fasted circulating g... 28 | 49
embryonic growth retardation 28 | 28
decreased lumbar vertebrae num... 27 | 62
decreased rib number 27 | 59
improved glucose tolerance 27 | 56
abnormal bone mineralization 26 | 55
decreased prepulse inhibition 26 | 52
abnormal heart morphology 24 | 51
decreased circulating alanine ... 24 | 53
abnormal eye morphology 23 | 38
abnormal gait 23 | 51
decreased circulating insulin ... 23 | 75
decreased hemoglobin content 23 | 53
increased circulating choleste... 23 | 53
increased sacral vertebrae num... 23 | 62
abnormal hindbrain development 22 | 24
decreased caudal vertebrae num... 22 | 49
decreased circulating alkaline... 22 | 41
increased startle reflex 22 | 38
male infertility 22 | 62
abnormal coat/hair pigmentatio... 21 | 54
increased blood urea nitrogen ... 21 | 44
increased bone mineral density 21 | 52
increased exploration in new e... 21 | 56
abnormal midbrain development 20 | 22
decreased leukocyte cell numbe... 20 | 54
decreased mean corpuscular hem... 20 | 34
increased leukocyte cell numbe... 20 | 37
small testis 20 | 37
thrombocytopenia 20 | 46
abnormal behavioral response t... 19 | 52
abnormal seminal vesicle morph... 19 | 47
decreased eosinophil cell numb... 19 | 41
increased circulating chloride... 19 | 43
limb grasping 19 | 35
abnormal testis morphology 18 | 30
abnormal tooth morphology 18 | 24
anophthalmia 18 | 20
decreased circulating LDL chol... 18 | 37
decreased startle reflex 18 | 48
hydrops fetalis 18 | 22
tremors 18 | 34
abnormal forebrain development 17 | 18
decreased circulating total pr... 17 | 41
decreased heart weight 17 | 44
increased body weight 17 | 42
abnormal cranium morphology 16 | 32
abnormal sleep behavior 16 | 63
cardiovascular system phenotyp... 16 | 35
increased circulating triglyce... 16 | 24
increased heart weight 16 | 37
prenatal lethality 16 | 16
abnormal embryo turning 15 | 15
corneal opacity 15 | 25
decreased blood urea nitrogen ... 15 | 31
decreased circulating calcium ... 15 | 33
enlarged lymph nodes 15 | 27
female infertility 15 | 34
increased circulating calcium ... 15 | 32

Disease

ovarian cancer 2,759 | 8,484
osteosarcoma 2,443 | 7,933
psoriasis 2,099 | 6,685
medulloblastoma, large-cell 1,968 | 6,234
glioblastoma 1,844 | 5,572
lung cancer 1,708 | 4,466
atypical teratoid / rhabdoid tumor 1,394 | 4,369
Cancer 1,358 | 2,346
malignant mesothelioma 1,180 | 3,162
Breast cancer 1,135 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 1,085 | 3,289
invasive ductal carcinoma 1,038 | 2,950
non-small cell lung cancer 1,013 | 2,798
primitive neuroectodermal tumor 996 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 993 | 2,988
pilocytic astrocytoma 980 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 974 | 2,956
oligodendroglioma 966 | 2,849
lung adenocarcinoma 956 | 2,713
pediatric high grade glioma 938 | 2,712
lung carcinoma 902 | 2,844
Carcinoma 858 | 2,147
pancreatic cancer 858 | 2,300
ependymoma 794 | 2,514
subependymal giant cell astrocytoma 762 | 2,287
interstitial cystitis 750 | 2,299
group 3 medulloblastoma 742 | 2,254
ulcerative colitis 727 | 2,087
astrocytic glioma 683 | 2,241
pituitary cancer 663 | 1,972
Pick disease 652 | 1,893
group 4 medulloblastoma 641 | 1,875
adult high grade glioma 638 | 2,148
breast carcinoma 622 | 1,614
ductal carcinoma in situ 620 | 1,745
colon cancer 604 | 1,475
astrocytoma 603 | 1,493
diabetes mellitus 594 | 1,663
cystic fibrosis 588 | 1,665
pancreatic ductal adenocarcinoma liver metastasis 550 | 1,795
tuberculosis 530 | 1,557
adrenocortical carcinoma 528 | 1,427
posterior fossa group A ependymoma 525 | 1,511
primary pancreatic ductal adenocarcinoma 506 | 1,271
Multiple myeloma 486 | 1,327
medulloblastoma 480 | 1,524
sonic hedgehog group medulloblastoma 466 | 1,482
acute quadriplegic myopathy 463 | 1,157
Rheumatoid Arthritis 459 | 1,160
juvenile dermatomyositis 456 | 1,189
posterior fossa group B ependymoma 403 | 1,530
dermatomyositis 401 | 933
atypical teratoid/rhabdoid tumor 361 | 1,095
cutaneous lupus erythematosus 348 | 1,056
spina bifida 348 | 1,064
nasopharyngeal carcinoma 344 | 1,056
Atopic dermatitis 330 | 944
Waldenstrons macroglobulinemia 321 | 765
gastric carcinoma 316 | 832
Alzheimer's disease 301 | 644
Intellectual disability 291 | 573
Obesity 289 | 616
active Crohn's disease 279 | 918
esophageal adenocarcinoma 271 | 737
primary Sjogren syndrome 262 | 789
Mammary Neoplasms 261 | 410
acute myeloid leukemia 260 | 780
Down syndrome 249 | 548
Prostatic Neoplasms 245 | 471
aldosterone-producing adenoma 245 | 664
Kidney disease 244 | 396
Duchenne muscular dystrophy 239 | 602
non primary Sjogren syndrome sicca 236 | 840
progressive supranuclear palsy 224 | 674
autosomal dominant Emery-Dreifuss muscular dystrophy 221 | 499
Endometriosis 219 | 535
Schizophrenia 211 | 501
Multiple Sclerosis 207 | 498
tuberculosis and treatment for 6 months 206 | 686
pancreatic carcinoma 204 | 567
Neurodegenerative disease 199 | 383
Amyotrophic Lateral Sclerosis 195 | 431
fibroadenoma 188 | 557
IGA Glomerulonephritis 187 | 454
hepatocellular carcinoma 184 | 532
Parkinson's disease 180 | 364
Autistic Disorder 178 | 320
Epilepsy 173 | 346
Vascular disease 168 | 281
Heart disease 167 | 279
Asthma 164 | 349
Hypertension 164 | 287
chronic rhinosinusitis 162 | 512
mucosa-associated lymphoid tissue lymphoma 161 | 480
non-small cell lung carcinoma 155 | 413
active ulcerative colitis 151 | 477
Stomach Neoplasms 150 | 282
gastric cancer 150 | 430
Anemia 148 | 252
Arthritis 147 | 248

Tissue

Nervous System 4,801 | 18,561
Female tissues 4,798 | 18,647
Endocrine System 4,797 | 18,512
Digestive Tract 4,794 | 18,473
Urinary Tract 4,781 | 18,444
Liver and Pancreas 4,773 | 18,136
Blood and immune system 4,753 | 17,995
Male tissues 4,752 | 17,969
Cardiovascular System 4,745 | 17,958
Skin and soft tissues 4,744 | 18,115
Respiratory system 4,691 | 17,484

Target Family

Non-IDG 2,388 | 11,971
Enzyme 1,116 | 4,146
Transcription Factor 573 | 1,400
Kinase 278 | 634
Transporter 120 | 473
Epigenetic 119 | 242
Ion Channel 102 | 341
GPCR 98 | 406
Nuclear Receptor 37 | 48
TF/Epigenetic 19 | 38

MGI Term

mortality/aging 4,850 | 4,850
homeostasis/metabolism phenoty... 4,454 | 4,454
growth/size/body region phenot... 3,915 | 3,915
cellular phenotype 3,348 | 3,348
nervous system phenotype 3,201 | 3,201
behavior/neurological phenotyp... 3,192 | 3,192
immune system phenotype 3,148 | 3,148
hematopoietic system phenotype 3,145 | 3,145
cardiovascular system phenotyp... 2,448 | 2,448
endocrine/exocrine gland pheno... 2,084 | 2,084
skeleton phenotype 2,058 | 2,058
normal phenotype 1,916 | 1,916
reproductive system phenotype 1,873 | 1,873
integument phenotype 1,748 | 1,748
embryo phenotype 1,674 | 1,674
vision/eye phenotype 1,478 | 1,478
muscle phenotype 1,385 | 1,385
digestive/alimentary phenotype 1,292 | 1,292
respiratory system phenotype 1,291 | 1,291
liver/biliary system phenotype 1,160 | 1,160
renal/urinary system phenotype 1,157 | 1,157
craniofacial phenotype 1,077 | 1,077
limbs/digits/tail phenotype 1,011 | 1,011
neoplasm 918 | 918
adipose tissue phenotype 901 | 901
hearing/vestibular/ear phenoty... 692 | 692
pigmentation phenotype 459 | 459
taste/olfaction phenotype 142 | 142
obsolete other phenotype 69 | 69

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955