Development Level

Tbio 801 | 11,445
Tchem 149 | 1,598
Tdark 64 | 6,588
Tclin 57 | 613

Collection

RFA-RM-18-021 8 | 328
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 133 | 979
preweaning lethality, incomple... 77 | 499
short tibia 57 | 97
abnormal embryo size 49 | 220
abnormal behavior 48 | 298
embryonic lethality prior to t... 47 | 278
abnormal bone structure 45 | 187
decreased total body fat amoun... 38 | 207
decreased body weight 35 | 161
increased total body fat amoun... 33 | 134
decreased body length 32 | 101
decreased bone mineral content 32 | 151
decreased lean body mass 32 | 135
decreased caudal vertebrae num... 28 | 53
enlarged heart 28 | 210
abnormal heart morphology 26 | 162
increased circulating alkaline... 26 | 122
increased lean body mass 26 | 172
embryonic lethality prior to o... 25 | 239
decreased bone mineral density 24 | 126
hypoactivity 23 | 132
increased startle reflex 23 | 112
decreased vertical activity 22 | 208
edema 21 | 59
hyperactivity 21 | 148
embryonic growth retardation 20 | 106
abnormal tail morphology 19 | 25
decreased circulating choleste... 19 | 93
decreased circulating glucose ... 19 | 126
decreased hemoglobin content 19 | 68
prenatal lethality prior to he... 19 | 87
decreased circulating serum al... 18 | 82
increased bone mineral content 18 | 108
increased or absent threshold ... 18 | 101
abnormal eye morphology 17 | 68
abnormal neural tube closure 17 | 46
decreased circulating HDL chol... 17 | 68
decreased grip strength 17 | 116
impaired glucose tolerance 17 | 75
abnormal craniofacial morpholo... 15 | 33
abnormal gait 15 | 69
abnormal limb bud morphology 15 | 17
abnormal retina morphology 15 | 71
abnormal seminal vesicle morph... 15 | 114
decreased erythrocyte cell num... 15 | 62
increased bone mineral density 15 | 72
abnormal cranium morphology 14 | 36
abnormal femur morphology 14 | 14
abnormal tibia morphology 14 | 14
decreased circulating alkaline... 14 | 46
decreased circulating triglyce... 14 | 79
abnormal coat-hair pigmentatio... 13 | 64
cataract 13 | 92
decreased circulating insulin ... 13 | 76
decreased prepulse inhibition 13 | 82
increased blood urea nitrogen ... 13 | 48
increased circulating HDL chol... 13 | 80
male infertility 13 | 123
abnormal limb morphology 12 | 13
decreased circulating total pr... 12 | 49
decreased lymphocyte cell numb... 12 | 83
increased circulating choleste... 12 | 66
increased heart weight 12 | 62
increased mean corpuscular vol... 12 | 92
pallor 12 | 34
thrombocytopenia 12 | 56
abnormal joint morphology 11 | 23
corneal opacity 11 | 32
decreased circulating calcium ... 11 | 36
increased mean corpuscular hem... 11 | 96
increased neutrophil cell numb... 11 | 46
limb grasping 11 | 41
pale yolk sac 11 | 25
prenatal lethality 11 | 28
abnormal facial morphology 10 | 17
abnormal snout morphology 10 | 23
abnormal vertebrae morphology 10 | 18
anophthalmia 10 | 33
enlarged lymph nodes 10 | 37
increased hemoglobin content 10 | 45
long tibia 10 | 25
small superior vagus ganglion 10 | 74
abnormal humerus morphology 9 | 11
abnormal kidney morphology 9 | 65
abnormal pericardium morpholog... 9 | 26
decreased blood urea nitrogen ... 9 | 51
decreased hematocrit 9 | 46
hemorrhage 9 | 23
increased circulating chloride... 9 | 41
increased circulating glucose ... 9 | 24
abnormal lens morphology 8 | 81
abnormal placenta size 8 | 20
cardiovascular system phenotyp... 8 | 36
decreased circulating iron lev... 8 | 32
decreased startle reflex 8 | 75
improved glucose tolerance 8 | 79
increased body weight 8 | 25
increased circulating amylase ... 8 | 25
increased circulating sodium l... 8 | 71
increased fasted circulating g... 8 | 76

Disease

Carcinoma 793 | 11,493
ovarian cancer 632 | 8,520
osteosarcoma 544 | 7,950
psoriasis 482 | 6,694
glioblastoma 449 | 5,792
medulloblastoma, large-cell 439 | 6,241
atypical teratoid / rhabdoid tumor 404 | 5,112
lung cancer 389 | 4,740
Breast cancer 364 | 3,578
ependymoma 358 | 4,679
Cancer 334 | 2,499
malignant mesothelioma 298 | 3,232
group 3 medulloblastoma 292 | 4,104
invasive ductal carcinoma 278 | 2,951
Kidney cancer 263 | 2,613
adult high grade glioma 260 | 3,801
Astrocytoma, Pilocytic 257 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 250 | 3,291
pancreatic cancer 250 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 249 | 2,955
non-small cell lung cancer 246 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 234 | 2,989
primitive neuroectodermal tumor 230 | 3,035
lung adenocarcinoma 212 | 2,716
oligodendroglioma 211 | 2,850
Autosomal recessive predisposition 209 | 1,442
lung carcinoma 208 | 2,843
interstitial cystitis 206 | 2,312
pituitary cancer 197 | 1,972
astrocytic glioma 185 | 2,597
ductal carcinoma in situ 184 | 1,745
breast carcinoma 169 | 1,638
cystic fibrosis 164 | 1,696
subependymal giant cell astrocytoma 164 | 2,287
ulcerative colitis 158 | 1,819
group 4 medulloblastoma 150 | 1,855
Intellectual disability 147 | 1,016
diabetes mellitus 144 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 141 | 1,962
Pick disease 136 | 1,894
Short stature 136 | 531
adrenocortical carcinoma 134 | 1,428
colon cancer 129 | 1,478
tuberculosis 129 | 2,010
primary pancreatic ductal adenocarcinoma 126 | 1,109
Schizophrenia 123 | 1,160
Rheumatoid arthritis 118 | 1,191
Dull intelligence 111 | 645
Low intelligence 111 | 645
Mental Retardation 111 | 645
Mental deficiency 111 | 645
Poor school performance 111 | 645
acute quadriplegic myopathy 106 | 1,158
astrocytoma 104 | 1,146
juvenile dermatomyositis 102 | 1,187
pediatric high grade glioma 101 | 1,064
Obesity 96 | 678
gastric carcinoma 96 | 807
Liver Cirrhosis, Experimental 94 | 769
Atopic dermatitis 92 | 952
Hypoplastic mandible condyle 92 | 275
Mandibular hypoplasia 92 | 275
Micrognathism 92 | 275
Cleft Palate 91 | 271
Osteoporosis 90 | 363
Breast Neoplasms 88 | 445
Muscle hypotonia 88 | 571
spina bifida 86 | 1,074
Mammary Neoplasms 85 | 425
Liver cancer 84 | 604
Multiple myeloma 84 | 1,332
Orbital separation excessive 84 | 244
nasopharyngeal carcinoma 84 | 1,058
Cognitive delay 81 | 608
Global developmental delay 81 | 608
Mental and motor retardation 81 | 608
dermatomyositis 81 | 966
Alzheimer's disease 80 | 658
Curvature of spine 80 | 282
Prostatic Neoplasms 80 | 495
Acquired scoliosis 79 | 281
Epilepsy 78 | 792
Melanoma 78 | 711
Small head 76 | 374
autosomal dominant Emery-Dreifuss muscular dystrophy 75 | 510
cutaneous lupus erythematosus 75 | 1,057
Duchenne muscular dystrophy 74 | 601
Seizures 74 | 596
active ulcerative colitis 73 | 764
Brachydactyly 71 | 156
active Crohn's disease 71 | 922
Craniofacial Abnormalities 70 | 151
Cryptorchidism 69 | 296
medulloblastoma 67 | 720
esophageal adenocarcinoma 66 | 737
hearing impairment 65 | 199
non primary Sjogren syndrome sicca 65 | 891
Bipolar Disorder 62 | 666
Endometriosis 62 | 540
Polydactyly 62 | 107

Tissue

Endocrine System 1,044 | 18,159
Female tissues 1,034 | 17,400
Digestive Tract 1,033 | 17,369
Skin and soft tissues 1,028 | 17,230
Male tissues 1,020 | 17,142
Urinary Tract 1,006 | 16,678
Liver and Pancreas 1,003 | 16,750
Blood and immune system 998 | 16,909
Nervous System 991 | 16,725
Respiratory system 983 | 16,393
Cardiovascular System 937 | 15,192

Target Family

Non-IDG 534 | 12,091
Enzyme 214 | 4,145
Transcription Factor 166 | 1,400
Kinase 60 | 634
Epigenetic 28 | 242
GPCR 28 | 408
Transporter 16 | 473
Ion Channel 11 | 344
Nuclear Receptor 11 | 48
TF/Epigenetic 3 | 38

MGI Phenotype

limbs-digits-tail phenotype 1,071 | 1,071
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RWD domain-containing protein 3 RWDD3 Tbio Non-IDG -1.02793 10.9 98
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Zinc transporter ZIP3 SLC39A3 Tbio Transporter -0.52290 3.15 87
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Cytochrome c oxidase assembly factor 5 COA5 Tdark Enzyme -0.77512 6.90 3
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38