Development Level

Tbio 1,246 | 11,445
Tchem 383 | 1,598
Tclin 170 | 613
Tdark 75 | 6,588

Collection

RFA-RM-18-021 20 | 328
Ion Channel: IDG Consortium (T... 10 | 99
Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Targets) 4 | 126
Kinase: IDG Consortium (Comple... 4 | 37
GPCR: IDG Consortium (Complete... 3 | 25

IMPC Phenotype

preweaning lethality, complete... 181 | 979
preweaning lethality, incomple... 90 | 499
abnormal behavior 59 | 298
abnormal embryo size 52 | 220
embryonic lethality prior to t... 52 | 278
abnormal coat-hair pigmentatio... 50 | 64
decreased total body fat amoun... 49 | 207
decreased body weight 48 | 161
enlarged heart 47 | 210
decreased vertical activity 45 | 208
abnormal bone structure 42 | 187
increased lean body mass 39 | 172
increased total body fat amoun... 36 | 134
embryonic lethality prior to o... 35 | 239
hypoactivity 34 | 132
abnormal heart morphology 32 | 162
increased startle reflex 31 | 112
decreased circulating glucose ... 30 | 126
abnormal skin morphology 29 | 50
abnormal seminal vesicle morph... 27 | 114
decreased bone mineral content 27 | 151
decreased circulating triglyce... 27 | 79
decreased bone mineral density 26 | 126
hyperactivity 26 | 148
increased mean corpuscular vol... 25 | 92
decreased circulating choleste... 24 | 93
decreased grip strength 23 | 116
edema 23 | 59
abnormal gait 22 | 69
decreased lean body mass 22 | 135
decreased prepulse inhibition 22 | 82
abnormal coat appearance 21 | 31
abnormal retina morphology 21 | 71
embryonic growth retardation 21 | 106
increased circulating alkaline... 21 | 122
abnormal vibrissa morphology 20 | 25
short tibia 20 | 97
abnormal eye morphology 19 | 68
decreased hemoglobin content 19 | 68
increased circulating choleste... 19 | 66
pallor 19 | 34
cataract 18 | 92
decreased circulating HDL chol... 18 | 68
decreased circulating serum al... 18 | 82
increased bone mineral content 18 | 108
decreased erythrocyte cell num... 17 | 62
increased heart weight 17 | 62
male infertility 17 | 123
small superior vagus ganglion 17 | 74
decreased body length 16 | 101
decreased circulating alkaline... 16 | 46
decreased circulating total pr... 16 | 49
decreased fasted circulating g... 16 | 65
decreased mean corpuscular vol... 16 | 79
increased circulating HDL chol... 16 | 80
increased fasted circulating g... 16 | 76
abnormal coat- hair morphology 15 | 19
abnormal skin coloration 15 | 25
impaired glucose tolerance 15 | 75
increased bone mineral density 15 | 72
increased mean corpuscular hem... 15 | 96
prenatal lethality prior to he... 15 | 87
abnormal bone mineralization 14 | 38
abnormal response to tactile s... 14 | 17
abnormal sleep behavior 14 | 70
decreased blood urea nitrogen ... 14 | 51
decreased circulating insulin ... 14 | 76
decreased lymphocyte cell numb... 14 | 83
increased circulating triglyce... 14 | 42
increased leukocyte cell numbe... 14 | 47
limb grasping 14 | 41
abnormal neural tube closure 13 | 46
decreased circulating LDL chol... 13 | 38
decreased circulating alanine ... 13 | 47
decreased startle reflex 13 | 75
increased hematocrit 13 | 46
increased hemoglobin content 13 | 45
increased or absent threshold ... 13 | 101
thrombocytopenia 13 | 56
tremors 13 | 39
abnormal epididymis morphology 12 | 42
abnormal kidney morphology 12 | 65
abnormal startle reflex 12 | 15
decreased hematocrit 12 | 46
decreased leukocyte cell numbe... 12 | 73
increased monocyte cell number 12 | 63
abnormal cranium morphology 11 | 36
female infertility 11 | 60
improved glucose tolerance 11 | 79
increased circulating calcium ... 11 | 34
increased circulating chloride... 11 | 41
increased neutrophil cell numb... 11 | 46
pale yolk sac 11 | 25
abnormal placenta size 10 | 20
abnormal spleen morphology 10 | 55
absent vibrissae 10 | 12
decreased circulating aspartat... 10 | 34
decreased circulating iron lev... 10 | 32
increased circulating sodium l... 10 | 71
small testis 10 | 58

Disease

Carcinoma 1,327 | 11,493
ovarian cancer 1,035 | 8,520
osteosarcoma 937 | 7,950
psoriasis 883 | 6,694
glioblastoma 754 | 5,792
medulloblastoma, large-cell 737 | 6,241
lung cancer 711 | 4,740
Cancer 678 | 2,499
atypical teratoid / rhabdoid tumor 631 | 5,112
Breast cancer 560 | 3,578
ependymoma 558 | 4,679
malignant mesothelioma 505 | 3,232
adult high grade glioma 486 | 3,801
group 3 medulloblastoma 472 | 4,104
Astrocytoma, Pilocytic 451 | 3,081
non-small cell lung cancer 451 | 2,890
invasive ductal carcinoma 443 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 432 | 3,291
Kidney cancer 411 | 2,613
pancreatic cancer 411 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 410 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 400 | 2,955
lung carcinoma 387 | 2,843
lung adenocarcinoma 384 | 2,716
primitive neuroectodermal tumor 382 | 3,035
oligodendroglioma 370 | 2,850
interstitial cystitis 359 | 2,312
Autosomal recessive predisposition 339 | 1,442
astrocytic glioma 323 | 2,597
pituitary cancer 306 | 1,972
subependymal giant cell astrocytoma 306 | 2,287
breast carcinoma 298 | 1,638
ulcerative colitis 288 | 1,819
ductal carcinoma in situ 285 | 1,745
diabetes mellitus 279 | 1,728
Schizophrenia 275 | 1,160
tuberculosis 274 | 2,010
cystic fibrosis 271 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 248 | 1,962
group 4 medulloblastoma 234 | 1,855
colon cancer 231 | 1,478
Intellectual disability 221 | 1,016
Pick disease 218 | 1,894
Epilepsy 204 | 792
adrenocortical carcinoma 204 | 1,428
primary pancreatic ductal adenocarcinoma 199 | 1,109
astrocytoma 195 | 1,146
Obesity 189 | 678
Rheumatoid arthritis 187 | 1,191
cutaneous lupus erythematosus 185 | 1,057
juvenile dermatomyositis 179 | 1,187
Bipolar Disorder 177 | 666
Seizures 176 | 596
Atopic dermatitis 174 | 952
acute quadriplegic myopathy 171 | 1,158
Dull intelligence 170 | 645
Low intelligence 170 | 645
Mental Retardation 170 | 645
Mental deficiency 170 | 645
Poor school performance 170 | 645
Short stature 169 | 531
spina bifida 169 | 1,074
Melanoma 163 | 711
Breast Neoplasms 160 | 445
Multiple myeloma 159 | 1,332
Depressive disorder 155 | 409
Mammary Neoplasms 155 | 425
nasopharyngeal carcinoma 153 | 1,058
Liver Cirrhosis, Experimental 151 | 769
esophageal adenocarcinoma 150 | 737
Alzheimer's disease 149 | 658
Cognitive delay 144 | 608
Global developmental delay 144 | 608
Mental and motor retardation 144 | 608
Prostatic Neoplasms 143 | 495
pediatric high grade glioma 143 | 1,064
gastric carcinoma 142 | 807
dermatomyositis 139 | 966
Hypertension 132 | 396
Liver cancer 125 | 604
Muscle hypotonia 125 | 571
aldosterone-producing adenoma 124 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 124 | 510
Duchenne muscular dystrophy 123 | 601
Kidney disease 119 | 430
active Crohn's disease 115 | 922
non primary Sjogren syndrome sicca 114 | 891
Mental Depression 113 | 333
active ulcerative colitis 111 | 764
Anemia 110 | 365
Endometriosis 110 | 540
Small head 110 | 374
Hypertensive disease 109 | 292
Asthma 107 | 385
Down syndrome 107 | 499
Cryptorchidism 105 | 296
Osteoporosis 105 | 363
primary Sjogren syndrome 105 | 735
Skin cancer 104 | 469
Vascular disease 104 | 319

Tissue

Endocrine System 1,837 | 18,159
Female tissues 1,808 | 17,400
Skin and soft tissues 1,807 | 17,230
Digestive Tract 1,803 | 17,369
Male tissues 1,777 | 17,142
Blood and immune system 1,764 | 16,909
Nervous System 1,750 | 16,725
Liver and Pancreas 1,748 | 16,750
Urinary Tract 1,747 | 16,678
Respiratory system 1,708 | 16,393
Cardiovascular System 1,615 | 15,192

Target Family

Non-IDG 840 | 12,091
Enzyme 419 | 4,145
Transcription Factor 220 | 1,400
Kinase 126 | 634
GPCR 83 | 408
Ion Channel 62 | 344
Transporter 58 | 473
Epigenetic 39 | 242
Nuclear Receptor 19 | 48
TF/Epigenetic 8 | 38

MGI Phenotype

integument phenotype 1,874 | 1,874
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Caspase-14 CASP14 Tchem Enzyme -1.81937 73.7 348
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Zinc transporter ZIP3 SLC39A3 Tbio Transporter -0.52290 3.15 87
LIM domain only protein 7 LMO7 Tbio Non-IDG -1.24771 19.7 80
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
Cytochrome c oxidase assembly factor 5 COA5 Tdark Enzyme -0.77512 6.90 3