Development Level

Tbio 3,353 | 11,651
Tchem 761 | 1,388
Tclin 358 | 612
Tdark 275 | 6,593

Collection

RFA-RM-18-021 60 | 328
GPCR: IDG Consortium (Targets) 23 | 126
Kinase: IDG Consortium (Target... 19 | 125
Ion Channel: IDG Consortium (T... 18 | 99
Kinase: IDG Consortium (Comple... 11 | 37
GPCR: IDG Consortium (Complete... 8 | 25

IMPC Phenotype

preweaning lethality, complete... 416 | 979
preweaning lethality, incomple... 254 | 499
abnormal behavior 163 | 298
decreased total body fat amoun... 133 | 207
embryonic lethality prior to t... 131 | 278
decreased body weight 110 | 161
decreased circulating glucose ... 110 | 126
abnormal bone structure 108 | 187
increased lean body mass 108 | 172
abnormal embryo size 103 | 220
decreased vertical activity 102 | 208
increased circulating alkaline... 102 | 122
enlarged heart 95 | 210
embryonic lethality prior to o... 91 | 239
decreased bone mineral content 85 | 151
increased total body fat amoun... 85 | 134
hypoactivity 84 | 132
decreased circulating choleste... 79 | 93
decreased circulating serum al... 75 | 82
abnormal heart morphology 73 | 162
decreased lean body mass 71 | 135
decreased bone mineral density 70 | 126
hyperactivity 68 | 148
decreased circulating insulin ... 66 | 76
decreased circulating triglyce... 65 | 79
increased circulating sodium l... 65 | 71
increased startle reflex 65 | 112
improved glucose tolerance 62 | 79
increased circulating HDL chol... 60 | 80
decreased circulating HDL chol... 57 | 68
decreased grip strength 56 | 116
increased fasted circulating g... 56 | 76
impaired glucose tolerance 55 | 75
abnormal seminal vesicle morph... 54 | 114
increased circulating choleste... 54 | 66
increased mean corpuscular hem... 54 | 96
decreased fasted circulating g... 52 | 65
decreased mean corpuscular vol... 52 | 79
increased bone mineral content 52 | 108
short tibia 52 | 97
decreased body length 51 | 101
cataract 50 | 92
increased mean corpuscular vol... 49 | 92
male infertility 49 | 123
abnormal retina morphology 46 | 71
abnormal sleep behavior 46 | 70
decreased prepulse inhibition 46 | 82
embryonic growth retardation 46 | 106
increased or absent threshold ... 46 | 101
decreased circulating alanine ... 44 | 47
abnormal lens morphology 43 | 81
decreased circulating total pr... 42 | 49
decreased hemoglobin content 42 | 68
increased bone mineral density 42 | 72
increased heart weight 42 | 62
abnormal gait 41 | 69
edema 40 | 59
thrombocytopenia 40 | 56
decreased leukocyte cell numbe... 38 | 73
increased blood urea nitrogen ... 38 | 48
increased circulating chloride... 38 | 41
decreased blood urea nitrogen ... 37 | 51
decreased circulating alkaline... 37 | 46
decreased lymphocyte cell numb... 37 | 83
decreased erythrocyte cell num... 36 | 62
increased leukocyte cell numbe... 36 | 47
decreased circulating LDL chol... 35 | 38
decreased startle reflex 35 | 75
decreased mean corpuscular hem... 34 | 50
prenatal lethality prior to he... 34 | 87
small superior vagus ganglion 34 | 74
abnormal eye morphology 33 | 68
abnormal kidney morphology 33 | 65
increased hemoglobin content 33 | 45
decreased circulating creatini... 32 | 39
increased circulating triglyce... 32 | 42
abnormal behavioral response t... 31 | 66
increased circulating calcium ... 31 | 34
decreased circulating free fat... 30 | 31
abnormal bone mineralization 29 | 38
decreased circulating calcium ... 29 | 36
limb grasping 29 | 41
decreased circulating aspartat... 28 | 34
increased circulating creatini... 28 | 38
abnormal coat-hair pigmentatio... 27 | 64
decreased circulating fructosa... 27 | 30
decreased circulating iron lev... 26 | 32
increased circulating potassiu... 26 | 29
increased neutrophil cell numb... 26 | 46
small testis 26 | 58
decreased circulating amylase ... 25 | 28
decreased hematocrit 25 | 46
female infertility 25 | 60
increased circulating iron lev... 25 | 30
increased hematocrit 25 | 46
abnormal cranium morphology 24 | 36
increased circulating total pr... 24 | 28
increased monocyte cell number 24 | 63
increased red blood cell distr... 24 | 34
tremors 24 | 39

Disease

Carcinoma 3,229 | 11,493
ovarian cancer 2,449 | 8,520
osteosarcoma 2,256 | 7,950
psoriasis 2,098 | 6,694
medulloblastoma, large-cell 1,848 | 6,241
glioblastoma 1,798 | 5,792
lung cancer 1,608 | 4,740
atypical teratoid / rhabdoid tumor 1,509 | 5,112
ependymoma 1,357 | 4,679
Cancer 1,300 | 2,499
group 3 medulloblastoma 1,195 | 4,104
Breast cancer 1,162 | 3,578
malignant mesothelioma 1,160 | 3,232
adult high grade glioma 1,140 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 1,070 | 3,291
invasive ductal carcinoma 1,031 | 2,951
lung carcinoma 1,031 | 2,843
Astrocytoma, Pilocytic 1,020 | 3,081
non-small cell lung cancer 1,014 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 1,013 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1,004 | 2,989
lung adenocarcinoma 947 | 2,716
pancreatic cancer 910 | 2,398
primitive neuroectodermal tumor 895 | 3,035
oligodendroglioma 870 | 2,850
Kidney cancer 838 | 2,613
interstitial cystitis 808 | 2,312
Autosomal recessive predisposition 779 | 1,442
astrocytic glioma 758 | 2,597
subependymal giant cell astrocytoma 745 | 2,287
tuberculosis 719 | 2,010
ulcerative colitis 707 | 1,819
pituitary cancer 690 | 1,972
diabetes mellitus 687 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 678 | 1,962
ductal carcinoma in situ 655 | 1,745
cystic fibrosis 624 | 1,696
breast carcinoma 614 | 1,638
Schizophrenia 591 | 1,160
Pick disease 568 | 1,894
colon cancer 562 | 1,478
group 4 medulloblastoma 545 | 1,855
adrenocortical carcinoma 521 | 1,428
Intellectual disability 459 | 1,016
Rheumatoid arthritis 441 | 1,191
Obesity 436 | 678
astrocytoma 424 | 1,146
juvenile dermatomyositis 417 | 1,187
primary pancreatic ductal adenocarcinoma 415 | 1,109
acute quadriplegic myopathy 409 | 1,158
cutaneous lupus erythematosus 404 | 1,057
Epilepsy 398 | 792
Multiple myeloma 357 | 1,332
Atopic dermatitis 352 | 952
pediatric high grade glioma 352 | 1,064
dermatomyositis 346 | 966
Liver Cirrhosis, Experimental 342 | 769
Dull intelligence 339 | 645
Low intelligence 339 | 645
Mental Retardation 339 | 645
Mental deficiency 339 | 645
Poor school performance 339 | 645
Bipolar Disorder 338 | 666
Seizures 336 | 596
spina bifida 334 | 1,074
active Crohn's disease 324 | 922
Alzheimer's disease 314 | 658
Cognitive delay 311 | 608
Global developmental delay 311 | 608
Mental and motor retardation 311 | 608
gastric carcinoma 311 | 807
nasopharyngeal carcinoma 311 | 1,058
Muscle hypotonia 303 | 571
Short stature 303 | 531
Hypertension 298 | 396
active ulcerative colitis 298 | 764
esophageal adenocarcinoma 289 | 737
Melanoma 287 | 711
Kidney disease 281 | 430
Prostatic Neoplasms 281 | 495
Depressive disorder 274 | 409
primary Sjogren syndrome 258 | 735
Breast Neoplasms 251 | 445
non primary Sjogren syndrome sicca 249 | 891
Mammary Neoplasms 243 | 425
medulloblastoma 241 | 720
acute myeloid leukemia 240 | 783
Hypertensive disease 238 | 292
Duchenne muscular dystrophy 237 | 601
Liver cancer 237 | 604
aldosterone-producing adenoma 234 | 665
Asthma 233 | 385
Down syndrome 226 | 499
Waldenstrons macroglobulinemia 226 | 765
Atherosclerosis 225 | 291
Endometriosis 222 | 540
Vascular disease 218 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 217 | 510
Multiple Sclerosis 212 | 540
progressive supranuclear palsy 212 | 676

Tissue

Endocrine System 4,628 | 18,159
Digestive Tract 4,581 | 17,369
Female tissues 4,539 | 17,400
Skin and soft tissues 4,533 | 17,230
Male tissues 4,485 | 17,142
Liver and Pancreas 4,464 | 16,750
Blood and immune system 4,454 | 16,909
Urinary Tract 4,449 | 16,678
Nervous System 4,405 | 16,725
Respiratory system 4,331 | 16,393
Cardiovascular System 4,075 | 15,192

Target Family

Non-IDG 2,269 | 12,091
Enzyme 1,162 | 4,145
Transcription Factor 375 | 1,400
Kinase 281 | 634
GPCR 197 | 408
Transporter 197 | 473
Ion Channel 127 | 344
Epigenetic 90 | 242
Nuclear Receptor 37 | 48
TF/Epigenetic 12 | 38

MGI Phenotype

homeostasis-metabolism phenoty... 4,747 | 4,747
mortality-aging 5,018 | 5,018
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184