Development Level

Tbio 3,145 | 11,178
Tchem 971 | 1,885
Tclin 358 | 612
Tdark 273 | 6,569

Collection

GPCR: IDG Consortium (Targets) 23 | 126
Kinase: IDG Consortium (Target... 19 | 125
Ion Channel: IDG Consortium (T... 18 | 99
Kinase: IDG Consortium (Comple... 11 | 37
GPCR: IDG Consortium (Complete... 8 | 25

IMPC Phenotype

preweaning lethality, complete... 416 | 979
preweaning lethality, incomple... 254 | 499
abnormal behavior 163 | 298
decreased total body fat amoun... 133 | 207
embryonic lethality prior to t... 131 | 278
decreased body weight 110 | 161
decreased circulating glucose ... 110 | 126
abnormal bone structure 108 | 187
increased lean body mass 108 | 172
abnormal embryo size 103 | 220
decreased vertical activity 102 | 208
increased circulating alkaline... 102 | 122
enlarged heart 95 | 210
embryonic lethality prior to o... 91 | 239
decreased bone mineral content 85 | 151
increased total body fat amoun... 85 | 134
hypoactivity 84 | 132
decreased circulating choleste... 79 | 93
decreased circulating serum al... 75 | 82
abnormal heart morphology 73 | 162
decreased lean body mass 71 | 135
decreased bone mineral density 70 | 126
hyperactivity 68 | 148
decreased circulating insulin ... 66 | 76
decreased circulating triglyce... 65 | 79
increased circulating sodium l... 65 | 71
increased startle reflex 65 | 112
improved glucose tolerance 62 | 79
increased circulating HDL chol... 60 | 80
decreased circulating HDL chol... 57 | 68
decreased grip strength 56 | 116
increased fasted circulating g... 56 | 76
impaired glucose tolerance 55 | 75
abnormal seminal vesicle morph... 54 | 114
increased circulating choleste... 54 | 66
increased mean corpuscular hem... 54 | 96
decreased fasted circulating g... 52 | 65
decreased mean corpuscular vol... 52 | 79
increased bone mineral content 52 | 108
short tibia 52 | 97
decreased body length 51 | 101
cataract 50 | 92
increased mean corpuscular vol... 49 | 92
male infertility 49 | 123
abnormal retina morphology 46 | 71
abnormal sleep behavior 46 | 70
decreased prepulse inhibition 46 | 82
embryonic growth retardation 46 | 106
increased or absent threshold ... 46 | 101
decreased circulating alanine ... 44 | 47
abnormal lens morphology 43 | 81
decreased circulating total pr... 42 | 49
decreased hemoglobin content 42 | 68
increased bone mineral density 42 | 72
increased heart weight 42 | 62
abnormal gait 41 | 69
edema 40 | 59
thrombocytopenia 40 | 56
decreased leukocyte cell numbe... 38 | 73
increased blood urea nitrogen ... 38 | 48
increased circulating chloride... 38 | 41
decreased blood urea nitrogen ... 37 | 51
decreased circulating alkaline... 37 | 46
decreased lymphocyte cell numb... 37 | 83
decreased erythrocyte cell num... 36 | 62
increased leukocyte cell numbe... 36 | 47
decreased circulating LDL chol... 35 | 38
decreased startle reflex 35 | 75
decreased mean corpuscular hem... 34 | 50
prenatal lethality prior to he... 34 | 87
small superior vagus ganglion 34 | 74
abnormal eye morphology 33 | 68
abnormal kidney morphology 33 | 65
increased hemoglobin content 33 | 45
decreased circulating creatini... 32 | 39
increased circulating triglyce... 32 | 42
abnormal behavioral response t... 31 | 66
increased circulating calcium ... 31 | 34
decreased circulating free fat... 30 | 31
abnormal bone mineralization 29 | 38
decreased circulating calcium ... 29 | 36
limb grasping 29 | 41
decreased circulating aspartat... 28 | 34
increased circulating creatini... 28 | 38
abnormal coat-hair pigmentatio... 27 | 64
decreased circulating fructosa... 27 | 30
decreased circulating iron lev... 26 | 32
increased circulating potassiu... 26 | 29
increased neutrophil cell numb... 26 | 46
small testis 26 | 58
decreased circulating amylase ... 25 | 28
decreased hematocrit 25 | 46
female infertility 25 | 60
increased circulating iron lev... 25 | 30
increased hematocrit 25 | 46
abnormal cranium morphology 24 | 36
increased circulating total pr... 24 | 28
increased monocyte cell number 24 | 63
increased red blood cell distr... 24 | 34
tremors 24 | 39

Disease

Carcinoma 3,124 | 11,192
ovarian cancer 2,368 | 8,297
osteosarcoma 2,197 | 7,766
psoriasis 2,031 | 6,514
medulloblastoma, large-cell 1,792 | 6,086
glioblastoma 1,747 | 5,635
lung cancer 1,554 | 4,607
atypical teratoid / rhabdoid tumor 1,462 | 4,971
ependymoma 1,324 | 4,559
Cancer 1,235 | 2,388
group 3 medulloblastoma 1,165 | 4,002
Breast cancer 1,121 | 3,469
malignant mesothelioma 1,120 | 3,135
adult high grade glioma 1,112 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 1,037 | 3,204
lung carcinoma 994 | 2,755
Astrocytoma, Pilocytic 993 | 3,006
invasive ductal carcinoma 992 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 979 | 2,872
non-small cell lung cancer 974 | 2,799
intraductal papillary-mucinous carcinoma (IPMC) 968 | 2,902
lung adenocarcinoma 908 | 2,627
pancreatic cancer 869 | 2,322
primitive neuroectodermal tumor 869 | 2,957
oligodendroglioma 846 | 2,768
Kidney cancer 813 | 2,548
interstitial cystitis 782 | 2,237
Autosomal recessive predisposition 755 | 1,407
astrocytic glioma 737 | 2,530
subependymal giant cell astrocytoma 727 | 2,230
tuberculosis 699 | 1,963
ulcerative colitis 679 | 1,765
pituitary cancer 672 | 1,915
diabetes mellitus 662 | 1,683
pancreatic ductal adenocarcinoma liver metastasis 657 | 1,911
ductal carcinoma in situ 622 | 1,686
cystic fibrosis 596 | 1,629
breast carcinoma 588 | 1,589
Schizophrenia 574 | 1,136
Pick disease 557 | 1,856
colon cancer 539 | 1,428
group 4 medulloblastoma 525 | 1,806
adrenocortical carcinoma 503 | 1,385
Intellectual disability 449 | 998
Rheumatoid arthritis 427 | 1,156
Obesity 424 | 655
astrocytoma 410 | 1,113
juvenile dermatomyositis 400 | 1,147
primary pancreatic ductal adenocarcinoma 396 | 1,071
acute quadriplegic myopathy 394 | 1,133
cutaneous lupus erythematosus 391 | 1,016
Epilepsy 387 | 775
Multiple myeloma 350 | 1,296
pediatric high grade glioma 337 | 1,035
Atopic dermatitis 335 | 915
dermatomyositis 335 | 941
Dull intelligence 333 | 634
Low intelligence 333 | 634
Mental Retardation 333 | 634
Mental deficiency 333 | 634
Poor school performance 333 | 634
spina bifida 329 | 1,053
Seizures 327 | 584
Bipolar Disorder 326 | 646
Liver Cirrhosis, Experimental 321 | 733
active Crohn's disease 309 | 882
Alzheimer's disease 304 | 640
Cognitive delay 302 | 596
Global developmental delay 302 | 596
Mental and motor retardation 302 | 596
nasopharyngeal carcinoma 299 | 1,024
gastric carcinoma 298 | 781
Muscle hypotonia 297 | 562
Short stature 288 | 514
active ulcerative colitis 288 | 736
Melanoma 282 | 689
Hypertension 280 | 372
esophageal adenocarcinoma 272 | 696
Depressive disorder 267 | 401
Kidney disease 264 | 411
Prostatic Neoplasms 264 | 472
primary Sjogren syndrome 253 | 710
non primary Sjogren syndrome sicca 238 | 861
Breast Neoplasms 237 | 423
medulloblastoma 234 | 702
Liver cancer 231 | 589
acute myeloid leukemia 231 | 760
Duchenne muscular dystrophy 230 | 587
Mammary Neoplasms 229 | 403
Hypertensive disease 226 | 278
aldosterone-producing adenoma 224 | 646
Asthma 222 | 370
Waldenstrons macroglobulinemia 221 | 742
Down syndrome 216 | 480
Atherosclerosis 211 | 276
Endometriosis 210 | 521
Failure to gain weight 207 | 359
Multiple Sclerosis 207 | 527
Pediatric failure to thrive 207 | 359
autosomal dominant Emery-Dreifuss muscular dystrophy 205 | 492

Tissue

Endocrine System 4,628 | 18,159
Digestive Tract 4,581 | 17,369
Female tissues 4,539 | 17,400
Skin and soft tissues 4,533 | 17,230
Male tissues 4,485 | 17,142
Liver and Pancreas 4,464 | 16,750
Blood and immune system 4,454 | 16,909
Urinary Tract 4,449 | 16,678
Nervous System 4,405 | 16,725
Respiratory system 4,331 | 16,393
Cardiovascular System 4,075 | 15,192

Target Family

Non-IDG 2,269 | 12,091
Enzyme 1,162 | 4,145
Transcription Factor 375 | 1,400
Kinase 281 | 634
GPCR 197 | 408
Transporter 197 | 473
Ion Channel 127 | 344
Epigenetic 90 | 242
Nuclear Receptor 37 | 48
TF/Epigenetic 12 | 38

MGI Phenotype

homeostasis-metabolism phenoty... 4,747 | 4,747
mortality-aging 5,018 | 5,018
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.72615 44.8 147
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Protein RCC2 RCC2 Tbio Non-IDG -1.49831 31.4 148
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 GCNT4 Tdark Enzyme -1.56850 33.7 45
Mitogen-activated protein kinase-binding protein 1 MAPKBP1 Tbio Enzyme -0.46630 4.01 51
Prominin-2 PROM2 Tbio Non-IDG -1.12562 11.0 199