Development Level

Tbio 2,363 | 11,445
Tchem 532 | 1,598
Tclin 289 | 613
Tdark 217 | 6,588

Collection

RFA-RM-18-021 70 | 328
Ion Channel: IDG Consortium (T... 26 | 99
GPCR: IDG Consortium (Targets) 24 | 126
Kinase: IDG Consortium (Target... 22 | 125
GPCR: IDG Consortium (Complete... 7 | 25
Kinase: IDG Consortium (Comple... 7 | 37

IMPC Phenotype

preweaning lethality, complete... 294 | 979
abnormal behavior 219 | 298
preweaning lethality, incomple... 199 | 499
hyperactivity 107 | 148
decreased total body fat amoun... 97 | 207
abnormal bone structure 96 | 187
hypoactivity 95 | 132
decreased vertical activity 87 | 208
increased lean body mass 85 | 172
decreased body weight 81 | 161
embryonic lethality prior to t... 79 | 278
decreased bone mineral content 73 | 151
increased total body fat amoun... 73 | 134
decreased grip strength 71 | 116
enlarged heart 70 | 210
increased circulating alkaline... 70 | 122
abnormal embryo size 65 | 220
decreased bone mineral density 65 | 126
abnormal sleep behavior 62 | 70
embryonic lethality prior to o... 59 | 239
increased startle reflex 59 | 112
decreased circulating glucose ... 58 | 126
decreased lean body mass 57 | 135
decreased startle reflex 56 | 75
abnormal gait 55 | 69
increased bone mineral content 52 | 108
decreased body length 50 | 101
decreased prepulse inhibition 50 | 82
abnormal behavioral response t... 49 | 66
abnormal seminal vesicle morph... 49 | 114
increased or absent threshold ... 49 | 101
short tibia 49 | 97
abnormal heart morphology 47 | 162
cataract 47 | 92
increased mean corpuscular vol... 46 | 92
abnormal retina morphology 44 | 71
decreased circulating triglyce... 42 | 79
decreased circulating choleste... 39 | 93
increased circulating choleste... 39 | 66
limb grasping 39 | 41
male infertility 39 | 123
abnormal lens morphology 38 | 81
decreased circulating serum al... 38 | 82
increased grip strength 37 | 41
decreased circulating insulin ... 36 | 76
decreased hemoglobin content 36 | 68
increased circulating HDL chol... 36 | 80
increased heart weight 36 | 62
impaired glucose tolerance 35 | 75
decreased fasted circulating g... 34 | 65
increased circulating sodium l... 34 | 71
tremors 34 | 39
decreased mean corpuscular vol... 32 | 79
increased bone mineral density 32 | 72
increased fasted circulating g... 32 | 76
increased mean corpuscular hem... 32 | 96
abnormal eye morphology 30 | 68
decreased leukocyte cell numbe... 30 | 73
improved glucose tolerance 30 | 79
prenatal lethality prior to he... 30 | 87
decreased circulating HDL chol... 29 | 68
embryonic growth retardation 29 | 106
decreased erythrocyte cell num... 28 | 62
increased circulating triglyce... 28 | 42
abnormal coat-hair pigmentatio... 26 | 64
edema 26 | 59
increased hemoglobin content 26 | 45
decreased lymphocyte cell numb... 25 | 83
impaired righting response 25 | 26
female infertility 24 | 60
increased circulating chloride... 24 | 41
thrombocytopenia 24 | 56
abnormal kidney morphology 23 | 65
increased blood urea nitrogen ... 23 | 48
abnormal bone mineralization 22 | 38
increased leukocyte cell numbe... 22 | 47
abnormal locomotor behavior 21 | 24
abnormal spleen morphology 21 | 55
decreased circulating alanine ... 21 | 47
decreased circulating amylase ... 21 | 28
decreased circulating total pr... 21 | 49
increased hematocrit 21 | 46
absent pinna reflex 20 | 23
corneal opacity 19 | 32
decreased caudal vertebrae num... 19 | 53
decreased circulating alkaline... 19 | 46
decreased hematocrit 19 | 46
increased circulating calcium ... 19 | 34
increased circulating creatini... 19 | 38
small testis 19 | 58
abnormal cornea morphology 18 | 31
abnormal vocalization 18 | 21
increased circulating potassiu... 18 | 29
increased prepulse inhibition 18 | 32
persistence of hyaloid vascula... 18 | 33
cardiovascular system phenotyp... 17 | 36
impaired pupillary reflex 17 | 26
increased erythrocyte cell num... 17 | 39
prolonged QT interval 17 | 38
prolonged ST segment 17 | 36

Disease

Carcinoma 2,381 | 11,493
ovarian cancer 1,745 | 8,520
osteosarcoma 1,521 | 7,950
medulloblastoma, large-cell 1,508 | 6,241
glioblastoma 1,478 | 5,792
psoriasis 1,419 | 6,694
atypical teratoid / rhabdoid tumor 1,333 | 5,112
ependymoma 1,178 | 4,679
lung cancer 1,121 | 4,740
adult high grade glioma 1,033 | 3,801
group 3 medulloblastoma 986 | 4,104
Astrocytoma, Pilocytic 889 | 3,081
Breast cancer 885 | 3,578
oligodendroglioma 838 | 2,850
malignant mesothelioma 812 | 3,232
primitive neuroectodermal tumor 807 | 3,035
Cancer 793 | 2,499
astrocytic glioma 732 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 727 | 3,291
Kidney cancer 718 | 2,613
lung carcinoma 707 | 2,843
invasive ductal carcinoma 706 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 687 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 673 | 2,989
non-small cell lung cancer 656 | 2,890
subependymal giant cell astrocytoma 629 | 2,287
lung adenocarcinoma 625 | 2,716
pancreatic cancer 581 | 2,398
pituitary cancer 580 | 1,972
Schizophrenia 576 | 1,160
Autosomal recessive predisposition 546 | 1,442
Pick disease 533 | 1,894
interstitial cystitis 508 | 2,312
tuberculosis 462 | 2,010
group 4 medulloblastoma 449 | 1,855
cystic fibrosis 447 | 1,696
ulcerative colitis 442 | 1,819
ductal carcinoma in situ 437 | 1,745
Intellectual disability 434 | 1,016
diabetes mellitus 423 | 1,728
breast carcinoma 420 | 1,638
Epilepsy 416 | 792
colon cancer 407 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 384 | 1,962
adrenocortical carcinoma 356 | 1,428
Bipolar Disorder 338 | 666
astrocytoma 317 | 1,146
Seizures 316 | 596
primary pancreatic ductal adenocarcinoma 296 | 1,109
Obesity 294 | 678
Dull intelligence 292 | 645
Low intelligence 292 | 645
Mental Retardation 292 | 645
Mental deficiency 292 | 645
Poor school performance 292 | 645
Rheumatoid arthritis 283 | 1,191
juvenile dermatomyositis 278 | 1,187
acute quadriplegic myopathy 268 | 1,158
Depressive disorder 263 | 409
Cognitive delay 258 | 608
Global developmental delay 258 | 608
Mental and motor retardation 258 | 608
Muscle hypotonia 257 | 571
Alzheimer's disease 253 | 658
pediatric high grade glioma 253 | 1,064
cutaneous lupus erythematosus 240 | 1,057
Multiple myeloma 232 | 1,332
Short stature 231 | 531
Liver Cirrhosis, Experimental 230 | 769
spina bifida 228 | 1,074
Liver cancer 226 | 604
Melanoma 225 | 711
Neurodegenerative disease 222 | 414
dermatomyositis 218 | 966
Atopic dermatitis 214 | 952
Mental Depression 211 | 333
Autistic Disorder 206 | 364
nasopharyngeal carcinoma 200 | 1,058
gastric carcinoma 199 | 807
active Crohn's disease 196 | 922
Parkinson's disease 195 | 392
Down syndrome 191 | 499
non primary Sjogren syndrome sicca 186 | 891
medulloblastoma 183 | 720
Duchenne muscular dystrophy 180 | 601
esophageal adenocarcinoma 174 | 737
Prostatic Neoplasms 173 | 495
active ulcerative colitis 170 | 764
Kidney disease 169 | 430
autosomal dominant Emery-Dreifuss muscular dystrophy 168 | 510
Breast Neoplasms 166 | 445
Major Depressive Disorder 166 | 301
Skin cancer 164 | 469
Hypertension 163 | 396
Mammary Neoplasms 163 | 425
aldosterone-producing adenoma 163 | 665
Alcoholic Intoxication, Chronic 161 | 289
Multiple Sclerosis 161 | 540
progressive supranuclear palsy 160 | 676
Cerebellar Ataxia 159 | 304

Tissue

Endocrine System 3,298 | 18,159
Digestive Tract 3,224 | 17,369
Skin and soft tissues 3,209 | 17,230
Female tissues 3,203 | 17,400
Nervous System 3,173 | 16,725
Male tissues 3,165 | 17,142
Liver and Pancreas 3,109 | 16,750
Blood and immune system 3,104 | 16,909
Urinary Tract 3,103 | 16,678
Respiratory system 3,032 | 16,393
Cardiovascular System 2,848 | 15,192

Target Family

Non-IDG 1,608 | 12,091
Enzyme 729 | 4,145
Transcription Factor 327 | 1,400
Kinase 178 | 634
GPCR 170 | 408
Ion Channel 161 | 344
Transporter 116 | 473
Epigenetic 68 | 242
Nuclear Receptor 33 | 48
TF/Epigenetic 11 | 38

MGI Phenotype

behavior-neurological phenotyp... 3,401 | 3,401
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase CMAHP Tbio Enzyme -1.76743 57.3 0
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 88
RWD domain-containing protein 3 RWDD3 Tbio Non-IDG -1.02793 10.9 98
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
UPF0606 protein KIAA1549 KIAA1549 Tbio Non-IDG -1.67668 47.8 19
Shadow of prion protein SPRN Tbio Non-IDG -2.49698 315.1 88
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Methyl-CpG-binding domain protein 1 MBD1 Tbio Transcription Factor -2.23809 171.1 297