Development Level

Tbio 2,305 | 11,178
Tchem 595 | 1,885
Tclin 289 | 612
Tdark 212 | 6,569

Collection

Ion Channel: IDG Consortium (T... 26 | 99
GPCR: IDG Consortium (Targets) 24 | 126
Kinase: IDG Consortium (Target... 22 | 125
GPCR: IDG Consortium (Complete... 7 | 25
Kinase: IDG Consortium (Comple... 7 | 37

IMPC Phenotype

preweaning lethality, complete... 294 | 979
abnormal behavior 219 | 298
preweaning lethality, incomple... 199 | 499
hyperactivity 107 | 148
decreased total body fat amoun... 97 | 207
abnormal bone structure 96 | 187
hypoactivity 95 | 132
decreased vertical activity 87 | 208
increased lean body mass 85 | 172
decreased body weight 81 | 161
embryonic lethality prior to t... 79 | 278
decreased bone mineral content 73 | 151
increased total body fat amoun... 73 | 134
decreased grip strength 71 | 116
enlarged heart 70 | 210
increased circulating alkaline... 70 | 122
abnormal embryo size 65 | 220
decreased bone mineral density 65 | 126
abnormal sleep behavior 62 | 70
embryonic lethality prior to o... 59 | 239
increased startle reflex 59 | 112
decreased circulating glucose ... 58 | 126
decreased lean body mass 57 | 135
decreased startle reflex 56 | 75
abnormal gait 55 | 69
increased bone mineral content 52 | 108
decreased body length 50 | 101
decreased prepulse inhibition 50 | 82
abnormal behavioral response t... 49 | 66
abnormal seminal vesicle morph... 49 | 114
increased or absent threshold ... 49 | 101
short tibia 49 | 97
abnormal heart morphology 47 | 162
cataract 47 | 92
increased mean corpuscular vol... 46 | 92
abnormal retina morphology 44 | 71
decreased circulating triglyce... 42 | 79
decreased circulating choleste... 39 | 93
increased circulating choleste... 39 | 66
limb grasping 39 | 41
male infertility 39 | 123
abnormal lens morphology 38 | 81
decreased circulating serum al... 38 | 82
increased grip strength 37 | 41
decreased circulating insulin ... 36 | 76
decreased hemoglobin content 36 | 68
increased circulating HDL chol... 36 | 80
increased heart weight 36 | 62
impaired glucose tolerance 35 | 75
decreased fasted circulating g... 34 | 65
increased circulating sodium l... 34 | 71
tremors 34 | 39
decreased mean corpuscular vol... 32 | 79
increased bone mineral density 32 | 72
increased fasted circulating g... 32 | 76
increased mean corpuscular hem... 32 | 96
abnormal eye morphology 30 | 68
decreased leukocyte cell numbe... 30 | 73
improved glucose tolerance 30 | 79
prenatal lethality prior to he... 30 | 87
decreased circulating HDL chol... 29 | 68
embryonic growth retardation 29 | 106
decreased erythrocyte cell num... 28 | 62
increased circulating triglyce... 28 | 42
abnormal coat-hair pigmentatio... 26 | 64
edema 26 | 59
increased hemoglobin content 26 | 45
decreased lymphocyte cell numb... 25 | 83
impaired righting response 25 | 26
female infertility 24 | 60
increased circulating chloride... 24 | 41
thrombocytopenia 24 | 56
abnormal kidney morphology 23 | 65
increased blood urea nitrogen ... 23 | 48
abnormal bone mineralization 22 | 38
increased leukocyte cell numbe... 22 | 47
abnormal locomotor behavior 21 | 24
abnormal spleen morphology 21 | 55
decreased circulating alanine ... 21 | 47
decreased circulating amylase ... 21 | 28
decreased circulating total pr... 21 | 49
increased hematocrit 21 | 46
absent pinna reflex 20 | 23
corneal opacity 19 | 32
decreased caudal vertebrae num... 19 | 53
decreased circulating alkaline... 19 | 46
decreased hematocrit 19 | 46
increased circulating calcium ... 19 | 34
increased circulating creatini... 19 | 38
small testis 19 | 58
abnormal cornea morphology 18 | 31
abnormal vocalization 18 | 21
increased circulating potassiu... 18 | 29
increased prepulse inhibition 18 | 32
persistence of hyaloid vascula... 18 | 33
cardiovascular system phenotyp... 17 | 36
impaired pupillary reflex 17 | 26
increased erythrocyte cell num... 17 | 39
prolonged QT interval 17 | 38
prolonged ST segment 17 | 36

Disease

Carcinoma 2,315 | 11,192
ovarian cancer 1,695 | 8,297
osteosarcoma 1,482 | 7,766
medulloblastoma, large-cell 1,467 | 6,086
glioblastoma 1,435 | 5,635
psoriasis 1,377 | 6,514
atypical teratoid / rhabdoid tumor 1,294 | 4,971
ependymoma 1,141 | 4,559
lung cancer 1,089 | 4,607
adult high grade glioma 1,007 | 3,701
group 3 medulloblastoma 958 | 4,002
Astrocytoma, Pilocytic 868 | 3,006
Breast cancer 860 | 3,469
oligodendroglioma 817 | 2,768
malignant mesothelioma 792 | 3,135
primitive neuroectodermal tumor 781 | 2,957
Cancer 756 | 2,388
astrocytic glioma 714 | 2,530
intraductal papillary-mucinous neoplasm (IPMN) 703 | 3,204
Kidney cancer 702 | 2,548
invasive ductal carcinoma 688 | 2,867
lung carcinoma 686 | 2,755
intraductal papillary-mucinous adenoma (IPMA) 666 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 646 | 2,902
non-small cell lung cancer 628 | 2,799
subependymal giant cell astrocytoma 609 | 2,230
lung adenocarcinoma 600 | 2,627
pituitary cancer 561 | 1,915
Schizophrenia 559 | 1,136
pancreatic cancer 559 | 2,322
Autosomal recessive predisposition 532 | 1,407
Pick disease 520 | 1,856
interstitial cystitis 494 | 2,237
tuberculosis 453 | 1,963
cystic fibrosis 430 | 1,629
group 4 medulloblastoma 429 | 1,806
ulcerative colitis 427 | 1,765
Intellectual disability 424 | 998
ductal carcinoma in situ 424 | 1,686
diabetes mellitus 409 | 1,683
breast carcinoma 407 | 1,589
Epilepsy 404 | 775
colon cancer 396 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 377 | 1,911
adrenocortical carcinoma 340 | 1,385
Bipolar Disorder 326 | 646
Seizures 308 | 584
astrocytoma 302 | 1,113
Dull intelligence 285 | 634
Low intelligence 285 | 634
Mental Retardation 285 | 634
Mental deficiency 285 | 634
Poor school performance 285 | 634
primary pancreatic ductal adenocarcinoma 284 | 1,071
Obesity 283 | 655
Rheumatoid arthritis 275 | 1,156
juvenile dermatomyositis 267 | 1,147
acute quadriplegic myopathy 262 | 1,133
Depressive disorder 255 | 401
Cognitive delay 252 | 596
Global developmental delay 252 | 596
Mental and motor retardation 252 | 596
Muscle hypotonia 251 | 562
Alzheimer's disease 247 | 640
pediatric high grade glioma 246 | 1,035
cutaneous lupus erythematosus 236 | 1,016
Multiple myeloma 226 | 1,296
Short stature 224 | 514
Liver cancer 222 | 589
spina bifida 222 | 1,053
Melanoma 221 | 689
Liver Cirrhosis, Experimental 218 | 733
Neurodegenerative disease 216 | 402
dermatomyositis 213 | 941
Mental Depression 204 | 325
Atopic dermatitis 203 | 915
Autistic Disorder 202 | 358
active Crohn's disease 191 | 882
gastric carcinoma 191 | 781
nasopharyngeal carcinoma 189 | 1,024
Parkinson's disease 186 | 378
Down syndrome 183 | 480
medulloblastoma 179 | 702
non primary Sjogren syndrome sicca 178 | 861
Duchenne muscular dystrophy 175 | 587
active ulcerative colitis 165 | 736
esophageal adenocarcinoma 164 | 696
Major Depressive Disorder 163 | 293
Prostatic Neoplasms 163 | 472
Kidney disease 162 | 411
Skin cancer 161 | 451
Breast Neoplasms 160 | 423
Alcoholic Intoxication, Chronic 158 | 283
autosomal dominant Emery-Dreifuss muscular dystrophy 158 | 492
Cerebellar Ataxia 157 | 302
Mammary Neoplasms 157 | 403
Multiple Sclerosis 157 | 527
Hypertension 154 | 372
aldosterone-producing adenoma 154 | 646
progressive supranuclear palsy 154 | 656

Tissue

Endocrine System 3,298 | 18,159
Digestive Tract 3,224 | 17,369
Skin and soft tissues 3,209 | 17,230
Female tissues 3,203 | 17,400
Nervous System 3,173 | 16,725
Male tissues 3,165 | 17,142
Liver and Pancreas 3,109 | 16,750
Blood and immune system 3,104 | 16,909
Urinary Tract 3,103 | 16,678
Respiratory system 3,032 | 16,393
Cardiovascular System 2,848 | 15,192

Target Family

Non-IDG 1,608 | 12,091
Enzyme 729 | 4,145
Transcription Factor 327 | 1,400
Kinase 178 | 634
GPCR 170 | 408
Ion Channel 161 | 344
Transporter 116 | 473
Epigenetic 68 | 242
Nuclear Receptor 33 | 48
TF/Epigenetic 11 | 38

MGI Phenotype

behavior-neurological phenotyp... 3,401 | 3,401
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
adipose tissue phenotype 992 | 992
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Probable gluconokinase IDNK Tbio Kinase -1.00330 9.91 94
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.72615 44.8 147
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 GCNT4 Tdark Enzyme -1.56850 33.7 45
Mitogen-activated protein kinase-binding protein 1 MAPKBP1 Tbio Enzyme -0.46630 4.01 51