Development Level

Tbio 656 | 11,445
Tchem 193 | 1,598
Tclin 88 | 613
Tdark 55 | 6,588

Collection

GPCR: IDG Consortium (Targets) 11 | 126
Kinase: IDG Consortium (Target... 6 | 125
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased total body fat amoun... 126 | 207
preweaning lethality, complete... 80 | 979
increased lean body mass 71 | 172
preweaning lethality, incomple... 69 | 499
increased total body fat amoun... 66 | 134
abnormal bone structure 62 | 187
decreased bone mineral content 52 | 151
decreased lean body mass 51 | 135
abnormal behavior 50 | 298
decreased body weight 46 | 161
increased bone mineral content 40 | 108
decreased body length 35 | 101
hypoactivity 34 | 132
decreased bone mineral density 32 | 126
increased circulating alkaline... 32 | 122
decreased circulating glucose ... 28 | 126
decreased vertical activity 28 | 208
decreased circulating choleste... 27 | 93
decreased circulating serum al... 26 | 82
embryonic lethality prior to t... 26 | 278
enlarged heart 26 | 210
short tibia 25 | 97
increased heart weight 24 | 62
abnormal sleep behavior 23 | 70
decreased circulating triglyce... 22 | 79
increased mean corpuscular hem... 22 | 96
hyperactivity 21 | 148
decreased circulating HDL chol... 20 | 68
increased mean corpuscular vol... 20 | 92
abnormal embryo size 19 | 220
abnormal heart morphology 19 | 162
decreased grip strength 19 | 116
decreased hemoglobin content 19 | 68
decreased prepulse inhibition 19 | 82
embryonic lethality prior to o... 19 | 239
increased bone mineral density 19 | 72
increased circulating HDL chol... 19 | 80
increased circulating choleste... 19 | 66
decreased circulating LDL chol... 18 | 38
decreased circulating alanine ... 18 | 47
increased startle reflex 18 | 112
abnormal seminal vesicle morph... 17 | 114
decreased circulating insulin ... 17 | 76
decreased mean corpuscular hem... 17 | 50
decreased startle reflex 17 | 75
decreased circulating total pr... 16 | 49
decreased mean corpuscular vol... 16 | 79
impaired glucose tolerance 16 | 75
increased hemoglobin content 16 | 45
abnormal behavioral response t... 15 | 66
abnormal gait 15 | 69
decreased leukocyte cell numbe... 15 | 73
decreased lymphocyte cell numb... 15 | 83
abnormal cranium morphology 14 | 36
abnormal retina morphology 14 | 71
improved glucose tolerance 14 | 79
increased blood urea nitrogen ... 14 | 48
increased mean platelet volume 14 | 45
limb grasping 14 | 41
decreased hematocrit 13 | 46
increased circulating sodium l... 13 | 71
increased fasted circulating g... 13 | 76
increased red blood cell distr... 13 | 34
thrombocytopenia 13 | 56
decreased circulating aspartat... 12 | 34
increased leukocyte cell numbe... 12 | 47
male infertility 12 | 123
abnormal kidney morphology 11 | 65
cataract 11 | 92
decreased blood urea nitrogen ... 11 | 51
decreased circulating alkaline... 11 | 46
decreased erythrocyte cell num... 11 | 62
edema 11 | 59
abnormal coat appearance 10 | 31
abnormal lens morphology 10 | 81
abnormal tooth morphology 10 | 24
decreased caudal vertebrae num... 10 | 53
decreased fasted circulating g... 10 | 65
increased circulating amylase ... 10 | 25
increased circulating chloride... 10 | 41
increased hematocrit 10 | 46
increased or absent threshold ... 10 | 101
abnormal spleen morphology 9 | 55
decreased circulating amylase ... 9 | 28
decreased circulating fructosa... 9 | 30
decreased circulating phosphat... 9 | 27
decreased heart weight 9 | 27
increased circulating iron lev... 9 | 30
increased circulating phosphat... 9 | 26
increased neutrophil cell numb... 9 | 46
abnormal bone mineralization 8 | 38
abnormal eye morphology 8 | 68
cardiovascular system phenotyp... 8 | 36
decreased circulating free fat... 8 | 31
decreased mean corpuscular hem... 8 | 31
decreased neutrophil cell numb... 8 | 42
impaired pupillary reflex 8 | 26
increased body length 8 | 32
increased circulating triglyce... 8 | 42
increased monocyte cell number 8 | 63

Disease

Carcinoma 703 | 11,493
ovarian cancer 545 | 8,520
osteosarcoma 486 | 7,950
psoriasis 472 | 6,694
medulloblastoma, large-cell 438 | 6,241
glioblastoma 388 | 5,792
lung cancer 361 | 4,740
atypical teratoid / rhabdoid tumor 327 | 5,112
ependymoma 297 | 4,679
Cancer 284 | 2,499
Breast cancer 266 | 3,578
group 3 medulloblastoma 266 | 4,104
invasive ductal carcinoma 262 | 2,951
malignant mesothelioma 253 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 244 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 241 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 236 | 2,989
non-small cell lung cancer 235 | 2,890
adult high grade glioma 230 | 3,801
Astrocytoma, Pilocytic 216 | 3,081
Kidney cancer 212 | 2,613
Obesity 210 | 678
diabetes mellitus 207 | 1,728
primitive neuroectodermal tumor 206 | 3,035
pancreatic cancer 199 | 2,398
lung adenocarcinoma 198 | 2,716
lung carcinoma 197 | 2,843
oligodendroglioma 194 | 2,850
ductal carcinoma in situ 184 | 1,745
pituitary cancer 181 | 1,972
interstitial cystitis 177 | 2,312
astrocytic glioma 174 | 2,597
Autosomal recessive predisposition 165 | 1,442
breast carcinoma 160 | 1,638
Schizophrenia 157 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 152 | 1,962
subependymal giant cell astrocytoma 151 | 2,287
tuberculosis 146 | 2,010
ulcerative colitis 146 | 1,819
Pick disease 140 | 1,894
group 4 medulloblastoma 136 | 1,855
adrenocortical carcinoma 133 | 1,428
cystic fibrosis 130 | 1,696
colon cancer 117 | 1,478
astrocytoma 114 | 1,146
acute quadriplegic myopathy 113 | 1,158
Intellectual disability 108 | 1,016
juvenile dermatomyositis 100 | 1,187
Depressive disorder 98 | 409
Bipolar Disorder 97 | 666
Atopic dermatitis 96 | 952
Rheumatoid arthritis 92 | 1,191
primary pancreatic ductal adenocarcinoma 92 | 1,109
Liver Cirrhosis, Experimental 91 | 769
dermatomyositis 91 | 966
Epilepsy 89 | 792
Short stature 87 | 531
pediatric high grade glioma 84 | 1,064
spina bifida 83 | 1,074
Hypertension 81 | 396
Prostatic Neoplasms 81 | 495
Multiple myeloma 80 | 1,332
Seizures 79 | 596
Dull intelligence 77 | 645
Hypertensive disease 77 | 292
Low intelligence 77 | 645
Mental Retardation 77 | 645
Mental deficiency 77 | 645
Poor school performance 77 | 645
Alzheimer's disease 74 | 658
Cognitive delay 74 | 608
Global developmental delay 74 | 608
Mental and motor retardation 74 | 608
active Crohn's disease 73 | 922
cutaneous lupus erythematosus 73 | 1,057
Breast Neoplasms 72 | 445
non primary Sjogren syndrome sicca 72 | 891
Mammary Neoplasms 71 | 425
Muscle hypotonia 71 | 571
nasopharyngeal carcinoma 71 | 1,058
Melanoma 70 | 711
gastric carcinoma 70 | 807
Down syndrome 69 | 499
autosomal dominant Emery-Dreifuss muscular dystrophy 69 | 510
aldosterone-producing adenoma 68 | 665
Mental Depression 67 | 333
fibroadenoma 67 | 559
Hyperglycemia 66 | 137
active ulcerative colitis 65 | 764
Polycystic ovary syndrome 63 | 360
Duchenne muscular dystrophy 60 | 601
Kidney disease 60 | 430
esophageal adenocarcinoma 59 | 737
Liver cancer 58 | 604
Parkinson's disease 58 | 392
Asthma 56 | 385
Atherosclerosis 56 | 291
Endometriosis 53 | 540
Heart disease 53 | 306
Osteoporosis 53 | 363

Tissue

Endocrine System 968 | 18,159
Digestive Tract 954 | 17,369
Female tissues 948 | 17,400
Skin and soft tissues 947 | 17,230
Male tissues 929 | 17,142
Liver and Pancreas 926 | 16,750
Urinary Tract 924 | 16,678
Blood and immune system 920 | 16,909
Nervous System 920 | 16,725
Respiratory system 904 | 16,393
Cardiovascular System 870 | 15,192

Target Family

Non-IDG 467 | 12,091
Enzyme 220 | 4,145
Transcription Factor 84 | 1,400
Kinase 64 | 634
GPCR 63 | 408
Epigenetic 35 | 242
Transporter 32 | 473
Nuclear Receptor 13 | 48
Ion Channel 8 | 344
TF/Epigenetic 6 | 38

MGI Phenotype

adipose tissue phenotype 992 | 992
mortality-aging 5,018 | 5,018
homeostasis-metabolism phenoty... 4,747 | 4,747
growth-size-body region phenot... 4,157 | 4,157
cellular phenotype 3,637 | 3,637
immune system phenotype 3,461 | 3,461
nervous system phenotype 3,447 | 3,447
behavior-neurological phenotyp... 3,401 | 3,401
hematopoietic system phenotype 3,383 | 3,383
cardiovascular system phenotyp... 2,660 | 2,660
endocrine-exocrine gland pheno... 2,293 | 2,293
skeleton phenotype 2,222 | 2,222
normal phenotype 1,999 | 1,999
reproductive system phenotype 1,999 | 1,999
integument phenotype 1,874 | 1,874
embryo phenotype 1,827 | 1,827
vision-eye phenotype 1,622 | 1,622
muscle phenotype 1,479 | 1,479
digestive-alimentary phenotype 1,398 | 1,398
respiratory system phenotype 1,390 | 1,390
liver-biliary system phenotype 1,300 | 1,300
renal-urinary system phenotype 1,269 | 1,269
craniofacial phenotype 1,182 | 1,182
limbs-digits-tail phenotype 1,071 | 1,071
neoplasm 975 | 975
hearing-vestibular-ear phenoty... 767 | 767
pigmentation phenotype 506 | 506
taste-olfaction phenotype 147 | 147
no phenotypic analysis 5 | 5

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
DnaJ homolog subfamily C member 15 DNAJC15 Tbio Non-IDG -1.67016 50.2 31
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Selenoprotein M SELENOM Tdark Non-IDG -1.51502 30.3 0
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221