Development Level

Tclin 73 | 613
Tbio 65 | 11,445
Tchem 60 | 1,598
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Targets) 4 | 126
Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 7 | 499
abnormal bone structure 6 | 187
increased startle reflex 6 | 112
increased heart weight 5 | 62
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased vertical activity 4 | 208
abnormal embryo size 3 | 220
decreased total body fat amoun... 3 | 207
edema 3 | 59
increased circulating alkaline... 3 | 122
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal epididymis morphology 2 | 42
abnormal skin morphology 2 | 50
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased circulating sodium l... 2 | 22
decreased circulating triglyce... 2 | 79
decreased mean corpuscular hem... 2 | 31
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired pupillary reflex 2 | 26
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
abnormal cornea morphology 1 | 31
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal tail length 1 | 3
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased anxiety-related resp... 1 | 12
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
scaly skin 1 | 4
thick skin 1 | 4
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 157 | 11,493
ovarian cancer 104 | 8,520
glioblastoma 93 | 5,792
psoriasis 91 | 6,694
medulloblastoma, large-cell 90 | 6,241
atypical teratoid / rhabdoid tumor 86 | 5,112
osteosarcoma 86 | 7,950
ependymoma 79 | 4,679
adult high grade glioma 73 | 3,801
Cancer 69 | 2,499
primitive neuroectodermal tumor 68 | 3,035
Schizophrenia 66 | 1,160
group 3 medulloblastoma 66 | 4,104
Kidney cancer 62 | 2,613
lung cancer 59 | 4,740
oligodendroglioma 59 | 2,850
Astrocytoma, Pilocytic 56 | 3,081
Breast cancer 54 | 3,578
astrocytic glioma 47 | 2,597
lung carcinoma 44 | 2,843
diabetes mellitus 43 | 1,728
Bipolar Disorder 42 | 666
subependymal giant cell astrocytoma 42 | 2,287
Depressive disorder 41 | 409
Epilepsy 41 | 792
invasive ductal carcinoma 41 | 2,951
lung adenocarcinoma 40 | 2,716
pancreatic cancer 38 | 2,398
Obesity 37 | 678
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
malignant mesothelioma 37 | 3,232
interstitial cystitis 36 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,291
Pick disease 35 | 1,894
Hypertension 34 | 396
Parkinson's disease 34 | 392
Mental Depression 33 | 333
non-small cell lung cancer 33 | 2,890
pituitary cancer 33 | 1,972
Seizures 31 | 596
colon cancer 30 | 1,478
ulcerative colitis 28 | 1,819
ductal carcinoma in situ 27 | 1,745
breast carcinoma 26 | 1,638
group 4 medulloblastoma 26 | 1,855
Heart disease 25 | 306
Major Depressive Disorder 25 | 301
Alcoholic Intoxication, Chronic 24 | 289
Intellectual disability 24 | 1,016
Autosomal recessive predisposition 23 | 1,442
Hypertensive disease 23 | 292
astrocytoma 23 | 1,146
Alzheimer's disease 22 | 658
Dull intelligence 22 | 645
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
Asthma 21 | 385
Mood Disorders 21 | 184
cystic fibrosis 21 | 1,696
tuberculosis 21 | 2,010
Atrial Fibrillation 20 | 124
Melanoma 20 | 711
Short stature 19 | 531
Substance Withdrawal Syndrome 19 | 55
Adenoma 18 | 167
Autistic Disorder 18 | 364
Cocaine-Related Disorders 18 | 92
Rheumatoid arthritis 18 | 1,191
Skin cancer 18 | 469
Unipolar Depression 18 | 250
Waldenstrons macroglobulinemia 18 | 765
Liver cancer 17 | 604
Multiple myeloma 17 | 1,332
Toxic encephalopathy 17 | 141
Cerebrovascular disease 16 | 238
Cognitive delay 16 | 608
Global developmental delay 16 | 608
Hyperactive behavior 16 | 91
Mental and motor retardation 16 | 608
Prostatic Neoplasms 16 | 495
adrenocortical carcinoma 16 | 1,428
Chronic heart failure 15 | 46
Muscle hypotonia 15 | 571
Polycystic ovary syndrome 15 | 360
Stomach Neoplasms 15 | 300
Endometrial cancer 14 | 311
General anesthesia 14 | 53
Migraine 14 | 83
Acquired scoliosis 13 | 281
Curvature of spine 13 | 282
Failure to gain weight 13 | 365
Orbital separation excessive 13 | 244
Vascular disease 13 | 319
acute quadriplegic myopathy 13 | 1,158
gastric carcinoma 13 | 807
juvenile dermatomyositis 13 | 1,187
non primary Sjogren syndrome sicca 13 | 891

Tissue

Endocrine System 197 | 18,159
Digestive Tract 192 | 17,369
Nervous System 191 | 16,725
Female tissues 186 | 17,400
Male tissues 186 | 17,142
Skin and soft tissues 186 | 17,230
Liver and Pancreas 184 | 16,750
Respiratory system 180 | 16,393
Urinary Tract 179 | 16,678
Blood and immune system 178 | 16,909
Cardiovascular System 168 | 15,192

Target Family

GPCR 41 | 408
Enzyme 38 | 4,145
Non-IDG 34 | 12,091
Kinase 28 | 634
Ion Channel 27 | 344
Transcription Factor 15 | 1,400
Transporter 15 | 473
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

KEGG Pathway

cAMP signaling pathway 201 | 201
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2 Tclin Ion Channel -1.16715 13.3 162
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108