Development Level

Tbio 22 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613

IMPC Phenotype

abnormal behavior 3 | 298
decreased bone mineral density 3 | 126
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
abnormal bone mineralization 1 | 38
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thin ventricular wall 1 | 24

Disease

Carcinoma 22 | 11,493
ovarian cancer 18 | 8,520
Autosomal recessive predisposition 14 | 1,442
psoriasis 14 | 6,694
lung cancer 13 | 4,740
osteosarcoma 13 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Cognitive delay 10 | 608
Epilepsy 10 | 792
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Muscle hypotonia 10 | 571
Seizures 10 | 596
Succinic semialdehyde dehydrogenase deficiency 9 | 16
ependymoma 9 | 4,679
glioblastoma 9 | 5,792
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
ulcerative colitis 8 | 1,819
Bipolar Disorder 7 | 666
Intellectual disability 7 | 1,016
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
acute myeloid leukemia 6 | 783
adult high grade glioma 6 | 3,801
nasopharyngeal carcinoma 6 | 1,058
non-small cell lung cancer 6 | 2,890
tuberculosis 6 | 2,010
Alcoholic Intoxication, Chronic 5 | 289
Liver Cirrhosis, Experimental 5 | 769
Metabolic acidosis 5 | 90
Schizophrenia 5 | 1,160
breast carcinoma 5 | 1,638
lung carcinoma 5 | 2,843
nephrosclerosis 5 | 333
non primary Sjogren syndrome sicca 5 | 891
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 364
Breast cancer 4 | 3,578
Highly variable clinical phenotype 4 | 150
Highly variable phenotype and severity 4 | 150
Highly variable phenotype, even within families 4 | 150
Kidney cancer 4 | 2,613
Lethargy 4 | 77
Mood Disorders 4 | 184
Obesity 4 | 678
Phenotypic variability 4 | 150
Short stature 4 | 531
Stomach Neoplasms 4 | 300
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
Abnormally small eyeball 3 | 97
Congenital anomaly of face 3 | 56
Decreased size of eyeball 3 | 97
Delayed speech and language development 3 | 112
Distortion of face 3 | 46
Dysmorphic facies 3 | 46
Dystonia 3 | 164
Dystonic disease 3 | 106
Funny looking face 3 | 46
Hepatomegaly 3 | 285
Hypoglycemia 3 | 152
Infantile onset 3 | 238
Kidney disease 3 | 430
Language Delay 3 | 112
Microphthalmos 3 | 100
Nystagmus 3 | 317
Osteoporosis 3 | 363
Pick disease 3 | 1,894
Small head 3 | 374
Speech Delay 3 | 112
Speech impairment 3 | 112
astrocytic glioma 3 | 2,597
chronic lymphosyte leukemia 3 | 204
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
facial deformity 3 | 46
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
lung adenocarcinoma 3 | 2,716
pediatric high grade glioma 3 | 1,064

Tissue

Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Blood and immune system 30 | 16,909
Female tissues 30 | 17,400
Urinary Tract 30 | 16,678
Respiratory system 29 | 16,393
Cardiovascular System 27 | 15,192

Target Family

Enzyme 29 | 4,145
Non-IDG 2 | 12,091

KEGG Pathway

beta-Alanine metabolism 31 | 31
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carnosine synthase 1 CARNS1 Tbio Enzyme -0.64427 4.21 70
Malonyl-CoA decarboxylase, mitochondrial MLYCD Tchem Enzyme -1.70434 46.1 67
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159
Spermine synthase SMS Tchem Enzyme -1.50353 28.6 215
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tbio Enzyme -1.43954 27.0 162
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.01557 101.4 321
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 Tbio Enzyme -1.18866 15.6 381
Spermidine synthase SRM Tchem Enzyme -1.65951 38.0 172
Aldehyde dehydrogenase family 1 member A3 ALDH1A3 Tbio Enzyme -1.98798 93.8 120