Development Level

Tbio 15 | 11,445
Tchem 7 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased anxiety-related resp... 1 | 2
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small kidney 1 | 16

Disease

Carcinoma 18 | 11,493
ovarian cancer 10 | 8,520
psoriasis 10 | 6,694
Autosomal recessive predisposition 9 | 1,442
osteosarcoma 8 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Kidney cancer 7 | 2,613
lung cancer 7 | 4,740
Anemia 6 | 365
Anemia, Megaloblastic 6 | 16
active ulcerative colitis 6 | 764
non-small cell lung cancer 6 | 2,890
Cancer 5 | 2,499
Liver Cirrhosis, Experimental 5 | 769
Obesity 5 | 678
Vitamin B12 deficiency 5 | 20
active Crohn's disease 5 | 922
biotin-responsive basal ganglia disease 5 | 8
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
Atherosclerosis 4 | 291
Breast cancer 4 | 3,578
Chemical and Drug Induced Liver Injury 4 | 195
Coronary artery disease 4 | 268
Lethargy 4 | 77
Lipid metabolism disorder 4 | 114
Megaloblastic anemia 4 | 18
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
subependymal giant cell astrocytoma 4 | 2,287
Adverse reaction to drug 3 | 61
Autistic Disorder 3 | 364
Biotin deficiency 3 | 10
Cardiovascular system disease 3 | 246
Cerebellar Ataxia 3 | 304
Colorectal Neoplasms 3 | 243
Decreased platelet count 3 | 111
Diarrhea 3 | 253
Drug-Related Side Effects and Adverse Reactions 3 | 62
Dull intelligence 3 | 645
Epilepsy 3 | 792
Hyperhomocysteinemia 3 | 37
Hypertension 3 | 396
Hypertensive disease 3 | 292
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Methylmalonic acidemia 3 | 37
Muscle hypotonia 3 | 571
Nystagmus 3 | 317
Optic Atrophy 3 | 242
Pallor 3 | 40
Paresthesia 3 | 32
Poor school performance 3 | 645
Proteinuria 3 | 144
Retinal Degeneration 3 | 106
Retinitis Pigmentosa 3 | 226
Schizophrenia 3 | 1,160
Seizures 3 | 596
Sensorineural Hearing Loss (disorder) 3 | 284
Steatorrhea 3 | 34
Thrombocytopenia 3 | 197
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
Adenocarcinoma of lung 2 | 142
Adenoma 2 | 167
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Cerebrovascular disease 2 | 238
Cholestasis 2 | 155
Dementia 2 | 175
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Failure to gain weight 2 | 365
Heart disease 2 | 306
Hepatomegaly 2 | 285
Homocystinuria 2 | 21
Hyperinsulinism 2 | 133
Kidney Diseases 2 | 114
Liver disease 2 | 237
Melanoma 2 | 711
Neutrophil count decreased 2 | 47
Pancytopenia 2 | 45
Pediatric failure to thrive 2 | 365
Sensorineural hearing loss 2 | 106
Skin cancer 2 | 469
Type 2 diabetes mellitus 2 | 272
Vomiting 2 | 116
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214

Tissue

Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Blood and immune system 23 | 16,909
Liver and Pancreas 23 | 16,750
Urinary Tract 23 | 16,678
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 10 | 12,091
Transporter 8 | 473
Enzyme 6 | 4,145

KEGG Pathway

Vitamin digestion and absorpti... 24 | 24
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Solute carrier family 23 member 1 SLC23A1 Tchem Transporter -1.82531 64.0 71
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Folate transporter 1 SLC19A1 Tchem Transporter -2.00363 97.7 67
Retinol-binding protein 2 RBP2 Tbio Non-IDG -2.08995 120.9 150
Acyl-CoA wax alcohol acyltransferase 2 AWAT2 Tbio Enzyme -1.73443 52.5 81
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.83573 76.5 233
Thiamine transporter 2 SLC19A3 Tbio Transporter -1.83955 73.2 85
Multidrug resistance-associated protein 1 ABCC1 Tchem Transporter -2.81072 662.2 328
Glutamate carboxypeptidase 2 FOLH1 Tchem Enzyme -3.08831 2219.0 855