Development Level

Tbio 161 | 10,625
Tchem 58 | 1,890
Tclin 21 | 602
Tdark 13 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
abnormal retina morphology 4 | 100
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 4 | 187
preweaning lethality, incomple... 4 | 260
abnormal embryo size 3 | 112
hypoactivity 3 | 89
increased circulating alkaline... 3 | 119
abnormal behavior 2 | 226
abnormal eye morphology 2 | 38
abnormal hindbrain development 2 | 24
abnormal lens morphology 2 | 73
abnormal neural tube closure 2 | 37
abnormal retinal pigmentation 2 | 61
abnormal testis morphology 2 | 30
cataract 2 | 26
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 31
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
hydrops fetalis 2 | 22
impaired glucose tolerance 2 | 52
increased circulating glucose ... 2 | 16
increased leukocyte cell numbe... 2 | 37
increased or absent threshold ... 2 | 128
short tibia 2 | 82
small testis 2 | 37
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal midbrain development 1 | 22
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 11
abnormal placenta size 1 | 10
abnormal seminal vesicle morph... 1 | 47
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
abnormal spinal cord morpholog... 1 | 8
abnormal spleen morphology 1 | 36
absent vibrissae 1 | 14
craniofacial phenotype 1 | 9
decreased CD103-positive CD11b... 1 | 2
decreased CD4-positive, CD25-p... 1 | 24
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased thermal nociceptive ... 1 | 4
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
herniated abdominal wall 1 | 4
improved glucose tolerance 1 | 56
increased circulating aspartat... 1 | 17
increased circulating free fat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased plasma cell number 1 | 5
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62
microphthalmia 1 | 15
pale yolk sac 1 | 12
prenatal lethality prior to he... 1 | 64
tremors 1 | 34
vertebral transformation 1 | 12

Disease

Cancer 167 | 2,346
psoriasis 147 | 6,685
ovarian cancer 113 | 8,484
osteosarcoma 86 | 7,933
lung cancer 82 | 4,466
diabetes mellitus 81 | 1,663
glioblastoma 75 | 5,572
Ankylosing spondylitis 72 | 138
medulloblastoma, large-cell 68 | 6,234
Rheumatoid Arthritis 66 | 1,160
Arthritis 64 | 248
Hypersensitivity reaction type II disease 61 | 235
Acquired immunodeficiency syndrome 60 | 164
Juvenile rheumatoid arthritis 58 | 104
Behcet's disease 56 | 74
Uveitis 56 | 103
Psoriatic arthritis 49 | 83
atypical teratoid / rhabdoid tumor 47 | 4,369
Multiple myeloma 45 | 1,327
pancreatic cancer 42 | 2,300
Breast cancer 41 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
invasive ductal carcinoma 41 | 2,950
malignant mesothelioma 41 | 3,162
Stevens-Johnson syndrome 39 | 78
pilocytic astrocytoma 39 | 3,086
subependymal giant cell astrocytoma 39 | 2,287
lung adenocarcinoma 38 | 2,713
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
astrocytoma 34 | 1,493
oligodendroglioma 34 | 2,849
primitive neuroectodermal tumor 34 | 3,031
ulcerative colitis 34 | 2,087
Multiple Sclerosis 33 | 498
Kidney disease 31 | 396
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,988
ependymoma 30 | 2,514
non-small cell lung cancer 29 | 2,798
pediatric high grade glioma 29 | 2,712
ductal carcinoma in situ 28 | 1,745
Carcinoma 27 | 2,147
adult high grade glioma 27 | 2,148
juvenile dermatomyositis 27 | 1,189
lung carcinoma 27 | 2,844
medulloblastoma 27 | 1,524
Anemia 26 | 252
Liver disease 26 | 219
dermatomyositis 26 | 933
colon cancer 25 | 1,475
Skin disease 24 | 65
breast carcinoma 24 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
Mammary Neoplasms 23 | 410
cystic fibrosis 23 | 1,665
Hemochromatosis 22 | 55
Hepatitis B 22 | 103
Primary immunodeficiency disease 22 | 52
astrocytic glioma 22 | 2,241
group 4 medulloblastoma 22 | 1,875
Leprosy 21 | 77
interstitial cystitis 21 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
posterior fossa group A ependymoma 21 | 1,511
tuberculosis 21 | 1,557
acute quadriplegic myopathy 20 | 1,157
adrenocortical carcinoma 20 | 1,427
Prostatic Neoplasms 19 | 471
cutaneous lupus erythematosus 19 | 1,056
Pick disease 18 | 1,893
Stomach Neoplasms 18 | 282
Waldenstrons macroglobulinemia 18 | 765
group 3 medulloblastoma 18 | 2,254
nasopharyngeal carcinoma 18 | 1,056
primary Sjogren syndrome 18 | 789
pancreatic carcinoma 17 | 567
pituitary cancer 17 | 1,972
primary pancreatic ductal adenocarcinoma 17 | 1,271
Liver carcinoma 16 | 217
acute myeloid leukemia 15 | 780
pre-eclampsia 15 | 67
Bladder Neoplasm 14 | 109
Endometriosis 14 | 535
Human immunodeficiency virus infectious disease 14 | 92
Lung Neoplasms 14 | 171
Schizophrenia 14 | 501
Atopic dermatitis 13 | 944
Mammary Neoplasms, Experimental 13 | 150
Melanoma 13 | 261
Peripheral T-cell lymphoma 13 | 24
Vascular disease 13 | 281
hepatocellular carcinoma 13 | 532
non-small cell lung carcinoma 13 | 413
sonic hedgehog group medulloblastoma 13 | 1,482
tuberculosis and treatment for 6 months 13 | 686
Animal Mammary Neoplasms 12 | 136
Colonic Neoplasms 12 | 126
IGA Glomerulonephritis 12 | 454
Intellectual disability 12 | 573

Tissue

Endocrine System 190 | 18,512
Blood and immune system 189 | 17,995
Female tissues 189 | 18,647
Nervous System 189 | 18,561
Urinary Tract 189 | 18,444
Cardiovascular System 188 | 17,958
Digestive Tract 188 | 18,473
Liver and Pancreas 188 | 18,136
Male tissues 188 | 17,969
Respiratory system 186 | 17,484
Skin and soft tissues 178 | 18,115

Target Family

Non-IDG 152 | 11,971
Enzyme 28 | 4,146
Transcription Factor 27 | 1,400
Kinase 24 | 634
Epigenetic 17 | 242
GPCR 4 | 406
TF/Epigenetic 1 | 38

KEGG Pathway

Viral carcinogenesis 253 | 253
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Interferon regulatory factor 9 IRF9 Tbio Transcription Factor -1.79340 61.7 168
HLA class I histocompatibility antigen, B-27 alpha chain HLA-B Tbio Non-IDG 1568.8 0
HLA class I histocompatibility antigen, B-38 alpha chain HLA-B Tbio Non-IDG 1568.8 0
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516