Development Level

Tbio 48 | 11,445
Tchem 37 | 1,598
Tclin 31 | 613
Tdark 7 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
preweaning lethality, complete... 6 | 979
increased startle reflex 5 | 112
abnormal bone structure 4 | 187
increased heart weight 4 | 62
abnormal behavior 3 | 298
cataract 3 | 92
decreased hematocrit 3 | 46
decreased total body fat amoun... 3 | 207
male infertility 3 | 123
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
edema 2 | 59
increased fasted circulating g... 2 | 76
abnormal duodenum morphology 1 | 4
abnormal facial morphology 1 | 17
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal placenta vasculature 1 | 2
abnormal sensory capabilities-... 1 | 8
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
respiratory system phenotype 1 | 2
short tibia 1 | 97
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 87 | 11,493
ovarian cancer 61 | 8,520
psoriasis 61 | 6,694
osteosarcoma 57 | 7,950
medulloblastoma, large-cell 55 | 6,241
lung cancer 51 | 4,740
atypical teratoid / rhabdoid tumor 48 | 5,112
glioblastoma 48 | 5,792
Kidney cancer 43 | 2,613
ependymoma 43 | 4,679
adult high grade glioma 40 | 3,801
lung adenocarcinoma 36 | 2,716
Breast cancer 35 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
primitive neuroectodermal tumor 34 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
lung carcinoma 32 | 2,843
Cancer 31 | 2,499
group 3 medulloblastoma 31 | 4,104
astrocytic glioma 30 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
non-small cell lung cancer 28 | 2,890
colon cancer 27 | 1,478
oligodendroglioma 27 | 2,850
Astrocytoma, Pilocytic 26 | 3,081
Hypertension 26 | 396
pancreatic cancer 26 | 2,398
invasive ductal carcinoma 25 | 2,951
malignant mesothelioma 24 | 3,232
Pick disease 23 | 1,894
interstitial cystitis 23 | 2,312
Schizophrenia 22 | 1,160
ulcerative colitis 20 | 1,819
pituitary cancer 19 | 1,972
subependymal giant cell astrocytoma 19 | 2,287
Bipolar Disorder 17 | 666
breast carcinoma 17 | 1,638
cystic fibrosis 16 | 1,696
group 4 medulloblastoma 16 | 1,855
Hypertensive disease 15 | 292
diabetes mellitus 15 | 1,728
tuberculosis 15 | 2,010
Autosomal recessive predisposition 14 | 1,442
Epilepsy 14 | 792
Liver cancer 14 | 604
Melanoma 14 | 711
Obesity 13 | 678
Asthma 12 | 385
Depressive disorder 12 | 409
Heart disease 12 | 306
Skin cancer 12 | 469
Cerebrovascular disease 11 | 238
Coronary artery disease 11 | 268
Hypertensive disorder 11 | 56
Rheumatoid arthritis 11 | 1,191
acute quadriplegic myopathy 11 | 1,158
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Intellectual disability 10 | 1,016
ductal carcinoma in situ 10 | 1,745
Cardiomegaly 9 | 116
Dull intelligence 9 | 645
Liver Cirrhosis, Experimental 9 | 769
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Mood Disorders 9 | 184
Parkinson's disease 9 | 392
Poor school performance 9 | 645
Seizures 9 | 596
Substance Withdrawal Syndrome 9 | 55
Toxic encephalopathy 9 | 141
adrenocortical carcinoma 9 | 1,428
spina bifida 9 | 1,074
Cognitive delay 8 | 608
Crohn's disease 8 | 321
Global developmental delay 8 | 608
Increase in blood pressure 8 | 119
Kidney disease 8 | 430
Mental and motor retardation 8 | 608
Multiple myeloma 8 | 1,332
Pulmonary hypertension 8 | 85
Waldenstrons macroglobulinemia 8 | 765
astrocytoma 8 | 1,146
cutaneous lupus erythematosus 8 | 1,057
juvenile dermatomyositis 8 | 1,187
pancreatic carcinoma 8 | 562
Alzheimer's disease 7 | 658
Angina Pectoris 7 | 32
Atherosclerosis 7 | 291
Endometrial cancer 7 | 311
Major Depressive Disorder 7 | 301
Muscle hypotonia 7 | 571
Nystagmus 7 | 317
Polycystic ovary syndrome 7 | 360
Short stature 7 | 531
Unipolar Depression 7 | 250
esophageal adenocarcinoma 7 | 737
medulloblastoma 7 | 720
nasopharyngeal carcinoma 7 | 1,058
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Digestive Tract 118 | 17,369
Endocrine System 118 | 18,159
Skin and soft tissues 118 | 17,230
Male tissues 116 | 17,142
Female tissues 115 | 17,400
Blood and immune system 114 | 16,909
Nervous System 113 | 16,725
Liver and Pancreas 112 | 16,750
Urinary Tract 112 | 16,678
Respiratory system 111 | 16,393
Cardiovascular System 103 | 15,192

Target Family

Enzyme 42 | 4,145
Non-IDG 31 | 12,091
Kinase 26 | 634
Ion Channel 13 | 344
GPCR 11 | 408

KEGG Pathway

Vascular smooth muscle contrac... 123 | 123
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Calcium-activated potassium channel subunit beta-4 KCNMB4 Tbio Ion Channel -0.98233 8.05 132
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Potassium channel subfamily U member 1 KCNU1 Tbio Ion Channel -1.65772 43.3 45
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Rho guanine nucleotide exchange factor 11 ARHGEF11 Tbio Non-IDG -1.61227 42.0 183