Development Level

Tchem 33 | 1,598
Tbio 14 | 11,445
Tclin 9 | 613
Tdark 2 | 6,588

IMPC Phenotype

decreased body weight 4 | 161
preweaning lethality, complete... 3 | 979
abnormal bone mineralization 2 | 38
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
increased circulating alkaline... 2 | 122
increased circulating glucose ... 2 | 24
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
male infertility 1 | 123
prenatal lethality 1 | 28
shortened RR interval 1 | 17
thrombocytosis 1 | 27

Disease

Carcinoma 43 | 11,493
Cancer 36 | 2,499
ovarian cancer 35 | 8,520
glioblastoma 30 | 5,792
psoriasis 29 | 6,694
osteosarcoma 28 | 7,950
lung cancer 25 | 4,740
medulloblastoma, large-cell 25 | 6,241
atypical teratoid / rhabdoid tumor 23 | 5,112
ependymoma 21 | 4,679
Breast cancer 18 | 3,578
Schizophrenia 18 | 1,160
adult high grade glioma 16 | 3,801
Kidney cancer 15 | 2,613
group 3 medulloblastoma 14 | 4,104
invasive ductal carcinoma 14 | 2,951
subependymal giant cell astrocytoma 14 | 2,287
group 4 medulloblastoma 13 | 1,855
interstitial cystitis 13 | 2,312
lung adenocarcinoma 13 | 2,716
primitive neuroectodermal tumor 13 | 3,035
Stomach Neoplasms 12 | 300
diabetes mellitus 12 | 1,728
oligodendroglioma 12 | 2,850
Breast Neoplasms 11 | 445
Intellectual disability 11 | 1,016
Mammary Neoplasms 11 | 425
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
ulcerative colitis 11 | 1,819
Astrocytoma, Pilocytic 10 | 3,081
Carcinoma, Squamous Cell 10 | 110
Depressive disorder 10 | 409
Epilepsy 10 | 792
Heart disease 10 | 306
Melanoma 10 | 711
Orbital separation excessive 10 | 244
Pick disease 10 | 1,894
Prostatic Neoplasms 10 | 495
Seizures 10 | 596
Squamous cell carcinoma 10 | 129
cystic fibrosis 10 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
tuberculosis 10 | 2,010
Bipolar Disorder 9 | 666
Cognitive delay 9 | 608
Concave bridge of nose 9 | 195
Depressed nasal bridge 9 | 195
Depressed nasal root/bridge 9 | 195
Dull intelligence 9 | 645
Global developmental delay 9 | 608
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental and motor retardation 9 | 608
Mental deficiency 9 | 645
Poor school performance 9 | 645
Renal Cell Carcinoma 9 | 214
Rheumatoid arthritis 9 | 1,191
astrocytic glioma 9 | 2,597
juvenile dermatomyositis 9 | 1,187
pancreatic cancer 9 | 2,398
Arthritis 8 | 290
Big calvaria 8 | 147
Blepharoptosis 8 | 231
Byzanthine arch palate 8 | 194
Colorectal Neoplasms 8 | 243
Downward slant of palpebral fissure 8 | 158
Frontal bossing 8 | 157
High forehead 8 | 102
Hypoplastic mandible condyle 8 | 275
Increased head circumference 8 | 147
Increased size of cranium 8 | 147
Increased size of skull 8 | 147
Lung Neoplasms 8 | 232
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Multiple myeloma 8 | 1,332
Neoplasm Metastasis 8 | 168
Tall forehead 8 | 102
Vascular disease 8 | 319
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
nasopharyngeal carcinoma 8 | 1,058
non-small cell lung cancer 8 | 2,890
Acquired scoliosis 7 | 281
Alzheimer's disease 7 | 658
Carcinoma, Hepatocellular 7 | 228
Curvature of spine 7 | 282
Kidney disease 7 | 430
Liver carcinoma 7 | 240
Mental Depression 7 | 333
Muscle hypotonia 7 | 571
Myopia 7 | 176
Pectus excavatum 7 | 100
Short stature 7 | 531
Telecanthus 7 | 62
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,428
pediatric high grade glioma 7 | 1,064

Tissue

Endocrine System 58 | 18,159
Blood and immune system 57 | 16,909
Digestive Tract 57 | 17,369
Female tissues 57 | 17,400
Skin and soft tissues 57 | 17,230
Male tissues 56 | 17,142
Liver and Pancreas 55 | 16,750
Nervous System 55 | 16,725
Respiratory system 55 | 16,393
Urinary Tract 55 | 16,678
Cardiovascular System 54 | 15,192

Target Family

Kinase 26 | 634
Enzyme 23 | 4,145
Non-IDG 8 | 12,091
Transcription Factor 1 | 1,400

KEGG Pathway

VEGF signaling pathway 58 | 58
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992