Development Level

Tchem 38 | 1,890
Tbio 11 | 10,625
Tclin 8 | 602
Tdark 3 | 7,003

IMPC Term

decreased body weight 4 | 174
abnormal bone mineralization 2 | 55
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating creatini... 2 | 31
decreased circulating triglyce... 2 | 83
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal optic disc morphology 1 | 10
abnormal respiratory quotient 1 | 9
cataract 1 | 26
decreased B cell number 1 | 30
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased total body fat amoun... 1 | 186
increased IgG1 level 1 | 1
increased T cell number 1 | 15
increased body length 1 | 20
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased heart rate 1 | 17
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
shortened RR interval 1 | 19
thrombocytosis 1 | 23

Disease

Cancer 35 | 2,346
ovarian cancer 35 | 8,484
osteosarcoma 30 | 7,933
psoriasis 29 | 6,685
glioblastoma 26 | 5,572
medulloblastoma, large-cell 25 | 6,234
lung cancer 23 | 4,466
atypical teratoid / rhabdoid tumor 21 | 4,369
Carcinoma 18 | 2,147
Breast cancer 17 | 3,094
invasive ductal carcinoma 16 | 2,950
subependymal giant cell astrocytoma 16 | 2,287
interstitial cystitis 15 | 2,299
medulloblastoma 15 | 1,524
ulcerative colitis 15 | 2,087
pediatric high grade glioma 14 | 2,712
pilocytic astrocytoma 14 | 3,086
lung adenocarcinoma 13 | 2,713
primitive neuroectodermal tumor 13 | 3,031
diabetes mellitus 12 | 1,663
oligodendroglioma 12 | 2,849
Mammary Neoplasms 11 | 410
Schizophrenia 11 | 501
ependymoma 11 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
Pick disease 10 | 1,893
Prostatic Neoplasms 10 | 471
Squamous cell carcinoma 10 | 94
adult high grade glioma 10 | 2,148
cystic fibrosis 10 | 1,665
group 4 medulloblastoma 10 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
malignant mesothelioma 10 | 3,162
non-small cell lung cancer 10 | 2,798
posterior fossa group A ependymoma 10 | 1,511
Lung Neoplasms 9 | 171
Rheumatoid Arthritis 9 | 1,160
Stomach Neoplasms 9 | 282
Vascular disease 9 | 281
juvenile dermatomyositis 9 | 1,189
non-small cell lung carcinoma 9 | 413
pancreatic cancer 9 | 2,300
Heart disease 8 | 279
Multiple myeloma 8 | 1,327
astrocytoma 8 | 1,493
colon cancer 8 | 1,475
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
lung carcinoma 8 | 2,844
nasopharyngeal carcinoma 8 | 1,056
Alzheimer's disease 7 | 644
Arthritis 7 | 248
Colorectal Neoplasms 7 | 217
Intellectual disability 7 | 573
Kidney disease 7 | 396
Liver carcinoma 7 | 217
Neoplasm Metastasis 7 | 138
Noonan Syndrome 7 | 33
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,427
posterior fossa group B ependymoma 7 | 1,530
tuberculosis 7 | 1,557
Adenoma 6 | 165
Autistic Disorder 6 | 320
Brain Ischemia 6 | 87
Cardiomegaly 6 | 66
Cardiomyopathies 6 | 90
Heart failure 6 | 80
Lung disease 6 | 132
Melanoma 6 | 261
Obesity 6 | 616
Parkinson's disease 6 | 364
Renal Cell Carcinoma 6 | 199
astrocytic glioma 6 | 2,241
dermatomyositis 6 | 933
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primary Sjogren syndrome 6 | 789
spina bifida 6 | 1,064
Adenocarcinoma 5 | 115
Colonic Neoplasms 5 | 126
Diarrhea 5 | 155
Hemangiosarcoma 5 | 18
Hyperalgesia 5 | 71
Hyperglycemia 5 | 120
Mouth Neoplasms 5 | 42
Myocardial Ischemia 5 | 169
Neoplasm Invasiveness 5 | 127
breast carcinoma 5 | 1,614
ovarian neoplasm 5 | 97
pancreatic carcinoma 5 | 567
Atherosclerosis 4 | 275
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Endometriosis 4 | 535
Hyperplasia 4 | 26
Reperfusion Injury 4 | 84
mucosa-associated lymphoid tissue lymphoma 4 | 480
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,271
tuberculosis and treatment for 6 months 4 | 686

Tissue

Cardiovascular System 60 | 17,958
Digestive Tract 60 | 18,473
Endocrine System 60 | 18,512
Female tissues 60 | 18,647
Liver and Pancreas 60 | 18,136
Male tissues 60 | 17,969
Nervous System 60 | 18,561
Respiratory system 60 | 17,484
Skin and soft tissues 60 | 18,115
Urinary Tract 60 | 18,444
Blood and immune system 59 | 17,995

Target Family

Kinase 27 | 634
Enzyme 24 | 4,146
Non-IDG 8 | 11,971
Transcription Factor 1 | 1,400

KEGG Pathway

VEGF signaling pathway 60 | 60
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
Mitogen-activated protein kinase 13 MAPK13 Tchem Kinase -2.46715 317.1 405
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.78634 57.0 688
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA Tchem Enzyme -2.95943 932.4 290
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.37849 233.2 634
Phosphoinositide 3-kinase regulatory subunit 5 PIK3R5 Tbio Enzyme -1.46850 26.8 198
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.60410 3186.8 1232
Cytosolic phospholipase A2 delta PLA2G4D Tdark Enzyme -0.49231 3.76 39