Development Level

Tbio 18 | 11,445
Tclin 11 | 613
Tchem 8 | 1,598

IMPC Phenotype

abnormal behavior 2 | 298
hyperactivity 2 | 148
preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal locomotor behavior 1 | 24
abnormal skin morphology 1 | 50
abnormal vocalization 1 | 21
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating sodium l... 1 | 71
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 26 | 11,493
psoriasis 20 | 6,694
Alcoholic Intoxication, Chronic 13 | 289
non-small cell lung cancer 13 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
ovarian cancer 12 | 8,520
Autosomal recessive predisposition 11 | 1,442
malignant mesothelioma 11 | 3,232
Alcohol dependence 10 | 107
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Breast cancer 9 | 3,578
Schizophrenia 9 | 1,160
ductal carcinoma in situ 9 | 1,745
Attention deficit hyperactivity disorder 8 | 278
Bipolar Disorder 8 | 666
Cancer 8 | 2,499
aldosterone-producing adenoma 8 | 665
breast carcinoma 8 | 1,638
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
nasopharyngeal carcinoma 8 | 1,058
Depressive disorder 7 | 409
adrenocortical carcinoma 7 | 1,428
osteosarcoma 7 | 7,950
Alcohol abuse 6 | 50
Major Depressive Disorder 6 | 301
Parkinson's disease 6 | 392
Pheochromocytoma 6 | 24
Unipolar Depression 6 | 250
atypical teratoid / rhabdoid tumor 6 | 5,112
colon cancer 6 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
medulloblastoma, large-cell 6 | 6,241
Astrocytoma, Pilocytic 5 | 3,081
Hypertension 5 | 396
Intellectual disability 5 | 1,016
Liver disease 5 | 237
Melanoma 5 | 711
Mental Depression 5 | 333
Mood Disorders 5 | 184
Tyrosinemia 5 | 10
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
esophageal adenocarcinoma 5 | 737
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
nephrosclerosis 5 | 333
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 364
Blepharoptosis 4 | 231
Endometriosis 4 | 540
Kidney cancer 4 | 2,613
Liver Cirrhosis, Experimental 4 | 769
Microphthalmia 4 | 76
Pancreatitis 4 | 123
Psychotic Disorders 4 | 151
Skin cancer 4 | 469
Substance abuse 4 | 59
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non primary Sjogren syndrome sicca 4 | 891
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Alcoholism 3 | 45
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Cocaine Dependence 3 | 51
Cognitive delay 3 | 608
Constipation 3 | 181
Coronary artery disease 3 | 268
Dementia 3 | 175
Dyschezia 3 | 135
Global developmental delay 3 | 608
Hypertyrosinemia 3 | 3
Hypotension 3 | 82
Liver carcinoma 3 | 240
Mental and motor retardation 3 | 608
Mouth Neoplasms 3 | 55
Muscle hypotonia 3 | 571
Oculocutaneous albinism 3 | 29
Organ system cancer 3 | 18
Parkinson Disease 3 | 64
Prostatic Neoplasms 3 | 495
Toxic encephalopathy 3 | 141
Tyrosinemias 3 | 3
acute myeloid leukemia 3 | 783
adrenocortical adenoma 3 | 131
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
esophageal cancer 3 | 22
fibroadenoma 3 | 559
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
hepatocellular carcinoma 3 | 547
oligodendroglioma 3 | 2,850
substance-related disorder 3 | 162
tuberculosis 3 | 2,010

Tissue

Female tissues 36 | 17,400
Skin and soft tissues 36 | 17,230
Blood and immune system 35 | 16,909
Endocrine System 35 | 18,159
Liver and Pancreas 35 | 16,750
Urinary Tract 35 | 16,678
Digestive Tract 34 | 17,369
Respiratory system 34 | 16,393
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Cardiovascular System 28 | 15,192

Target Family

Enzyme 35 | 4,145
Non-IDG 2 | 12,091

KEGG Pathway

Tyrosine metabolism 37 | 37
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fumarylacetoacetase FAH Tbio Enzyme -2.39887 253.3 196
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
Alcohol dehydrogenase class 4 mu/sigma chain ADH7 Tchem Enzyme -2.18765 159.0 243
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme -0.92913 14.1 37
Homogentisate 1,2-dioxygenase HGD Tbio Enzyme -2.62003 404.9 159
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.90323 857.6 277