Development Level

Tbio 17 | 11,445
Tchem 17 | 1,598
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
decreased circulating creatini... 2 | 39
decreased fasted circulating g... 2 | 65
impaired glucose tolerance 2 | 75
increased circulating alanine ... 2 | 13
increased mean corpuscular hem... 2 | 96
preweaning lethality, incomple... 2 | 499
abnormal gait 1 | 69
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 38 | 11,493
Cancer 26 | 2,499
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 24 | 5,112
glioblastoma 23 | 5,792
medulloblastoma, large-cell 21 | 6,241
diabetes mellitus 20 | 1,728
osteosarcoma 20 | 7,950
ependymoma 19 | 4,679
ovarian cancer 19 | 8,520
Hyperglycemia 18 | 137
adult high grade glioma 17 | 3,801
Obesity 15 | 678
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Breast cancer 14 | 3,578
Schizophrenia 14 | 1,160
group 3 medulloblastoma 14 | 4,104
primitive neuroectodermal tumor 14 | 3,035
Astrocytoma, Pilocytic 13 | 3,081
Diabetes Mellitus, Experimental 13 | 108
Diabetes Mellitus, Non-Insulin-Dependent 13 | 145
Kidney cancer 13 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
invasive ductal carcinoma 13 | 2,951
oligodendroglioma 13 | 2,850
Autosomal recessive predisposition 12 | 1,442
Diabetes Mellitus, Type 2 12 | 142
Epilepsy 12 | 792
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung cancer 12 | 4,740
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Hyperinsulinism 11 | 133
Insulin Resistance 11 | 72
Mental and motor retardation 11 | 608
Hypertension 10 | 396
Intellectual disability 10 | 1,016
lung adenocarcinoma 10 | 2,716
subependymal giant cell astrocytoma 10 | 2,287
Alzheimer's disease 9 | 658
Bipolar Disorder 9 | 666
Failure to gain weight 9 | 365
Hypoglycemia 9 | 152
Neuropathy 9 | 261
Pediatric failure to thrive 9 | 365
Peripheral Neuropathy 9 | 134
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
Arthritis 8 | 290
Carcinoma, Hepatocellular 8 | 228
Diabetes Mellitus, Noninsulin-Dependent 8 | 31
Fetal Growth Retardation 8 | 189
Hyperalgesia 8 | 83
Infant, Small for Gestational Age 8 | 176
Intrauterine retardation 8 | 176
Liver Cirrhosis, Experimental 8 | 769
Liver carcinoma 8 | 240
Seizures 8 | 596
dermatomyositis 8 | 966
ductal carcinoma in situ 8 | 1,745
juvenile dermatomyositis 8 | 1,187
non-small cell lung cancer 8 | 2,890
tuberculosis 8 | 2,010
Disease Models, Animal 7 | 155
Heart disease 7 | 306
Hypertensive disease 7 | 292
Low Birth Weights 7 | 69
Polycystic ovary syndrome 7 | 360
Small for gestational age (disorder) 7 | 69
Tonic - clonic seizures 7 | 44
Type 2 diabetes mellitus 7 | 272
Vascular disease 7 | 319
Weight decreased 7 | 103
astrocytic glioma 7 | 2,597
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
pituitary cancer 7 | 1,972
Abnormality of the immune system 6 | 18
Blepharoptosis 6 | 231
Congenital clinodactyly 6 | 57
Curvature of digit 6 | 57
Diarrhea 6 | 253
Dull intelligence 6 | 645
Endometrial cancer 6 | 311
Kidney disease 6 | 430
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Myocardial Ischemia 6 | 169
Parkinson's disease 6 | 392
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Radially deviated fingers 6 | 38
Rheumatoid arthritis 6 | 1,191
Stomach Neoplasms 6 | 300
adrenocortical carcinoma 6 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962

Tissue

Digestive Tract 46 | 17,369
Endocrine System 45 | 18,159
Nervous System 45 | 16,725
Skin and soft tissues 45 | 17,230
Liver and Pancreas 44 | 16,750
Female tissues 43 | 17,400
Male tissues 43 | 17,142
Blood and immune system 42 | 16,909
Urinary Tract 42 | 16,678
Respiratory system 39 | 16,393
Cardiovascular System 38 | 15,192

Target Family

Kinase 22 | 634
Non-IDG 10 | 12,091
Ion Channel 7 | 344
Transporter 3 | 473
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400

KEGG Pathway

Type II diabetes mellitus 46 | 46
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.22763 14.8 224
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
Pyruvate kinase PKLR PKLR Tbio Kinase -2.37549 231.1 391
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
Pyruvate kinase PKM PKM Tchem Kinase -3.15332 1424.2 749
Transcription factor MafA MAFA Tbio Transcription Factor -1.36099 23.0 195
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
ATP-binding cassette sub-family C member 8 ABCC8 Tclin Transporter -2.92120 869.9 193
Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A Tchem Ion Channel -3.06226 1140.1 64