Development Level

Tbio 109 | 11,445
Tchem 6 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
increased leukocyte cell numbe... 2 | 47
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
abnormal cecum morphology 1 | 7
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal spleen morphology 1 | 55
aorta stenosis 1 | 2
decreased T cell number 1 | 15
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged liver 1 | 2
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
short tibia 1 | 97
small spleen 1 | 19
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Cancer 87 | 2,499
diabetes mellitus 84 | 1,728
Hypersensitivity reaction type II disease 77 | 253
Ankylosing spondylitis 73 | 140
Behcet's disease 71 | 89
psoriasis 69 | 6,694
Arthritis 67 | 290
Juvenile rheumatoid arthritis 65 | 111
Rheumatoid arthritis 65 | 1,191
Acquired immunodeficiency syndrome 60 | 197
Uveitis 60 | 103
Herpes zoster 57 | 68
Human immunodeficiency virus infectious disease 55 | 138
Psoriatic arthritis 54 | 86
Stevens-Johnson syndrome 52 | 92
Carcinoma 51 | 11,493
dermatomyositis 44 | 966
Dermatitis 43 | 157
Multiple Sclerosis 42 | 540
tuberculosis 38 | 2,010
Behcet's syndrome 37 | 50
Synovitis 37 | 78
Takayasu's arteritis 37 | 53
Nephritis 36 | 51
Congenital adrenal hyperplasia 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
Hepatitis B 32 | 108
Anemia 30 | 365
Leprosy 30 | 73
Liver disease 30 | 237
Kidney disease 28 | 430
Primary immunodeficiency disease 27 | 54
lung carcinoma 26 | 2,843
lung cancer 25 | 4,740
Hemochromatosis 23 | 54
Skin disease 22 | 66
glioblastoma 22 | 5,792
Birdshot chorioretinopathy 21 | 23
sarcoidosis 20 | 370
Astrocytoma, Pilocytic 19 | 3,081
Schizophrenia 19 | 1,160
interstitial cystitis 19 | 2,312
Systemic lupus erythematosus 18 | 194
Berylliosis 17 | 28
Narcolepsy 17 | 72
ovarian cancer 17 | 8,520
adult high grade glioma 16 | 3,801
Human immunodeficiency virus type 1, susceptibility to 15 | 26
Pre-Eclampsia 15 | 68
cutaneous lupus erythematosus 15 | 1,057
osteosarcoma 15 | 7,950
Asthma 14 | 385
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Psoriasis susceptibility 1 14 | 14
Diffuse cutaneous systemic sclerosis 13 | 17
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
ependymoma 13 | 4,679
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
subependymal giant cell astrocytoma 13 | 2,287
Vasculitis 12 | 80
invasive ductal carcinoma 12 | 2,951
Fever 11 | 138
ulcerative colitis 11 | 1,819
Bipolar Disorder 10 | 666
Type 1 diabetes mellitus 10 | 109
breast carcinoma 10 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
juvenile dermatomyositis 10 | 1,187
Duchenne muscular dystrophy 9 | 601
Hypersensitivity 9 | 63
Inflammatory bowel disease 9 | 151
active Crohn's disease 9 | 922
astrocytoma 9 | 1,146
medulloblastoma, large-cell 9 | 6,241
primary Sjogren syndrome 9 | 735
Arthritis, Rheumatoid 8 | 174
Chemical and Drug Induced Liver Injury 8 | 195
Diarrhea 8 | 253
Leukopenia 8 | 72
Lung disease 8 | 142
Seizures 8 | 596
active ulcerative colitis 8 | 764
atypical teratoid / rhabdoid tumor 8 | 5,112
cystic fibrosis 8 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Allergic hypersensitivity disease 7 | 126
Atherosclerosis 7 | 291
Coronary artery disease 7 | 268
adrenocortical carcinoma 7 | 1,428
esophageal adenocarcinoma 7 | 737
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398

Tissue

Digestive Tract 38 | 17,369
Liver and Pancreas 38 | 16,750
Blood and immune system 37 | 16,909
Endocrine System 37 | 18,159
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Female tissues 36 | 17,400
Male tissues 35 | 17,142
Urinary Tract 35 | 16,678
Nervous System 33 | 16,725
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 116 | 12,091
Enzyme 6 | 4,145

KEGG Pathway

Type I diabetes mellitus 122 | 122
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

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