Development Level

Tbio 106 | 10,625
Tchem 59 | 1,890
Tclin 16 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 7 | 633
decreased grip strength 5 | 123
decreased lean body mass 4 | 195
decreased mean corpuscular vol... 4 | 50
increased circulating alkaline... 4 | 119
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
embryonic lethality prior to t... 3 | 187
increased erythrocyte cell num... 3 | 26
abnormal behavior 2 | 226
abnormal femur morphology 2 | 14
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular hem... 2 | 19
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
increased circulating fructosa... 2 | 11
increased circulating sodium l... 2 | 71
preweaning lethality, incomple... 2 | 260
short tibia 2 | 82
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal fibula morphology 1 | 2
abnormal forebrain development 1 | 18
abnormal glucose homeostasis 1 | 5
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal respiratory quotient 1 | 9
abnormal rib morphology 1 | 28
abnormal scapula morphology 1 | 3
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
absent mammary gland 1 | 1
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased B cell number 1 | 30
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased heart weight 1 | 44
decreased neutrophil cell numb... 1 | 37
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 22
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased NK cell number 1 | 19
increased body weight 1 | 42
increased circulating LDL chol... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased respiratory quotient 1 | 12
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62
polydactyly 1 | 22
premature death 1 | 5
shortened head 1 | 2
small heart 1 | 8
small kidney 1 | 10
small ovary 1 | 1
small spleen 1 | 11
small superior vagus ganglion 1 | 20
straub tail 1 | 26
thin skin 1 | 1
thrombocytosis 1 | 23
vertebral fusion 1 | 23

Disease

ovarian cancer 91 | 8,484
Cancer 85 | 2,346
psoriasis 82 | 6,685
osteosarcoma 81 | 7,933
glioblastoma 76 | 5,572
lung cancer 65 | 4,466
lung carcinoma 58 | 2,844
medulloblastoma, large-cell 55 | 6,234
tuberculosis 55 | 1,557
pilocytic astrocytoma 51 | 3,086
diabetes mellitus 50 | 1,663
ulcerative colitis 49 | 2,087
invasive ductal carcinoma 43 | 2,950
subependymal giant cell astrocytoma 42 | 2,287
Rheumatoid Arthritis 40 | 1,160
malignant mesothelioma 40 | 3,162
Multiple Sclerosis 39 | 498
atypical teratoid / rhabdoid tumor 37 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
interstitial cystitis 35 | 2,299
Arthritis 33 | 248
Asthma 32 | 349
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
adult high grade glioma 31 | 2,148
Hypersensitivity reaction type II disease 30 | 235
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,988
pediatric high grade glioma 30 | 2,712
Breast cancer 28 | 3,094
Kidney disease 28 | 396
pancreatic cancer 28 | 2,300
Multiple myeloma 27 | 1,327
astrocytoma 27 | 1,493
non-small cell lung cancer 27 | 2,798
primary Sjogren syndrome 27 | 789
posterior fossa group A ependymoma 25 | 1,511
Inflammatory bowel disease 24 | 142
cutaneous lupus erythematosus 24 | 1,056
Alzheimer's disease 22 | 644
Carcinoma 22 | 2,147
Obesity 22 | 616
Vascular disease 22 | 281
cystic fibrosis 22 | 1,665
dermatomyositis 22 | 933
primitive neuroectodermal tumor 22 | 3,031
adrenocortical carcinoma 21 | 1,427
breast carcinoma 21 | 1,614
Liver disease 20 | 219
ependymoma 20 | 2,514
lung adenocarcinoma 20 | 2,713
mucosa-associated lymphoid tissue lymphoma 20 | 480
periodontitis 20 | 269
Lung disease 19 | 132
Prostatic Neoplasms 19 | 471
group 4 medulloblastoma 19 | 1,875
juvenile dermatomyositis 19 | 1,189
medulloblastoma 19 | 1,524
oligodendroglioma 19 | 2,849
Mammary Neoplasms 18 | 410
Waldenstrons macroglobulinemia 18 | 765
Brain Ischemia 17 | 87
Dermatitis 17 | 107
Heart disease 17 | 279
Malaria 17 | 140
colon cancer 17 | 1,475
esophageal adenocarcinoma 17 | 737
Atherosclerosis 16 | 275
Crohn's disease 16 | 304
IGA Glomerulonephritis 16 | 454
Reperfusion Injury 16 | 84
active Crohn's disease 16 | 918
astrocytic glioma 16 | 2,241
group 3 medulloblastoma 16 | 2,254
sarcoidosis 16 | 358
Anemia 15 | 252
Influenza 15 | 142
Lung Neoplasms 15 | 171
Pneumonia 15 | 133
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
pituitary cancer 15 | 1,972
Hepatitis B 14 | 103
primary pancreatic ductal adenocarcinoma 14 | 1,271
Allergic hypersensitivity disease 13 | 123
Duchenne muscular dystrophy 13 | 602
Hepatitis C 13 | 90
Hypersensitivity 13 | 63
Inflammation 13 | 109
Schizophrenia 13 | 501
Thrombocytopenia 13 | 105
Toxic encephalopathy 13 | 131
Vasculitis 13 | 64
ductal carcinoma in situ 13 | 1,745
head and neck cancer and chronic obstructive pulmonary disease 13 | 237
pancreatic carcinoma 13 | 567
posterior fossa group B ependymoma 13 | 1,530
Crohn Disease 12 | 97
Down syndrome 12 | 548
Myocardial Ischemia 12 | 169
Pick disease 12 | 1,893
acute quadriplegic myopathy 12 | 1,157
gastric carcinoma 12 | 832

Tissue

Nervous System 177 | 18,561
Digestive Tract 175 | 18,473
Female tissues 175 | 18,647
Urinary Tract 175 | 18,444
Blood and immune system 170 | 17,995
Endocrine System 170 | 18,512
Liver and Pancreas 169 | 18,136
Respiratory system 167 | 17,484
Cardiovascular System 166 | 17,958
Skin and soft tissues 166 | 18,115
Male tissues 164 | 17,969

Target Family

Non-IDG 115 | 11,971
Kinase 30 | 634
Enzyme 29 | 4,146
Transcription Factor 10 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

KEGG Pathway

Tuberculosis 187 | 187
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 337
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.76384 47.5 542
Interleukin-10 receptor subunit beta IL10RB Tbio Non-IDG -1.82576 55.5 177
HLA class II histocompatibility antigen, DRB1-9 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0
Ras-related protein Rab-5C RAB5C Tbio Enzyme -1.13458 11.1 135
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.60609 403.7 216
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.51989 315.7 757