Development Level

Tbio 22 | 11,445
Tchem 13 | 1,598
Tclin 5 | 613

IMPC Phenotype

abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
increased lean body mass 2 | 172
microphthalmia 2 | 26
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
small superior vagus ganglion 1 | 74

Disease

Carcinoma 33 | 11,493
ovarian cancer 20 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
psoriasis 19 | 6,694
invasive ductal carcinoma 15 | 2,951
lung cancer 15 | 4,740
interstitial cystitis 13 | 2,312
Autosomal recessive predisposition 12 | 1,442
osteosarcoma 12 | 7,950
Major Depressive Disorder 11 | 301
Unipolar Depression 11 | 250
ductal carcinoma in situ 11 | 1,745
lung adenocarcinoma 11 | 2,716
lung carcinoma 11 | 2,843
malignant mesothelioma 11 | 3,232
breast carcinoma 10 | 1,638
colon cancer 10 | 1,478
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
Bipolar Disorder 9 | 666
Liver Cirrhosis, Experimental 9 | 769
Schizophrenia 9 | 1,160
ependymoma 9 | 4,679
medulloblastoma, large-cell 9 | 6,241
non-small cell lung cancer 9 | 2,890
ulcerative colitis 9 | 1,819
Breast cancer 8 | 3,578
adrenocortical carcinoma 8 | 1,428
glioblastoma 8 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Cancer 7 | 2,499
Cognitive delay 7 | 608
Depressive disorder 7 | 409
Global developmental delay 7 | 608
Mental Depression 7 | 333
Mental and motor retardation 7 | 608
Muscle hypotonia 7 | 571
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
nephrosclerosis 7 | 333
pancreatic cancer 7 | 2,398
Alcohol dependence 6 | 107
Alcoholic Intoxication, Chronic 6 | 289
Atopic dermatitis 6 | 952
Autistic Disorder 6 | 364
Hepatomegaly 6 | 285
Intellectual disability 6 | 1,016
atypical teratoid / rhabdoid tumor 6 | 5,112
cutaneous lupus erythematosus 6 | 1,057
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Dull intelligence 5 | 645
Endometriosis 5 | 540
Hypotension 5 | 82
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Obesity 5 | 678
Parkinson's disease 5 | 392
Poor school performance 5 | 645
Succinic semialdehyde dehydrogenase deficiency 5 | 16
Waldenstrons macroglobulinemia 5 | 765
adult high grade glioma 5 | 3,801
primary Sjogren syndrome 5 | 735
Attention deficit hyperactivity disorder 4 | 278
Breast Neoplasms 4 | 445
Cholestasis 4 | 155
Depression, Bipolar 4 | 12
Hypertension 4 | 396
Liver disease 4 | 237
Mammary Neoplasms 4 | 425
Metabolic acidosis 4 | 90
Mood Disorders 4 | 184
Multiple myeloma 4 | 1,332
Pellagra 4 | 26
Psychotic Disorders 4 | 151
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
substance-related disorder 4 | 162
Alzheimer's disease 3 | 658
Asthma 3 | 385
Hypoglycemia 3 | 152
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
astrocytic glioma 3 | 2,597
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
head and neck cancer 3 | 271
mucosa-associated lymphoid tissue lymphoma 3 | 484
primitive neuroectodermal tumor 3 | 3,035

Tissue

Endocrine System 40 | 18,159
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Male tissues 38 | 17,142
Urinary Tract 38 | 16,678
Skin and soft tissues 37 | 17,230
Cardiovascular System 35 | 15,192

Target Family

Enzyme 35 | 4,145
Non-IDG 5 | 12,091

KEGG Pathway

Tryptophan metabolism 40 | 40
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
2-oxoglutarate dehydrogenase-like, mitochondrial OGDHL Tbio Enzyme -0.59292 3.63 46
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tbio Enzyme -1.43954 27.0 162
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Kynurenine--oxoglutarate transaminase 3 KYAT3 Tbio Enzyme -0.86445 6.75 59
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
2-oxoglutarate dehydrogenase, mitochondrial OGDH Tbio Enzyme -2.47825 290.5 147
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH Tbio Enzyme -2.48697 296.4 389
Kynureninase KYNU Tchem Enzyme -1.61116 39.2 173