Development Level

Tbio 113 | 11,445
Tchem 37 | 1,598
Tclin 21 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 16 | 979
abnormal embryo size 7 | 220
decreased vertical activity 6 | 208
preweaning lethality, incomple... 6 | 499
enlarged heart 5 | 210
abnormal bone mineralization 4 | 38
abnormal heart morphology 4 | 162
decreased circulating choleste... 4 | 93
abnormal bone structure 3 | 187
female infertility 3 | 60
impaired glucose tolerance 3 | 75
increased bone mineral density 3 | 72
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
male infertility 3 | 123
short tibia 3 | 97
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal lung morphology 2 | 26
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating sodium l... 2 | 22
decreased leukocyte cell numbe... 2 | 73
decreased monocyte cell number 2 | 8
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
prenatal lethality prior to he... 2 | 87
small testis 2 | 58
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
absent vibrissae 1 | 12
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
increased B cell number 1 | 9
increased cardiac muscle contr... 1 | 8
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 47
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
polycystic kidney 1 | 15
prenatal lethality 1 | 28
shortened RR interval 1 | 17

Disease

Cancer 124 | 2,499
Carcinoma 117 | 11,493
ovarian cancer 106 | 8,520
osteosarcoma 104 | 7,950
psoriasis 93 | 6,694
glioblastoma 91 | 5,792
lung cancer 76 | 4,740
medulloblastoma, large-cell 70 | 6,241
malignant mesothelioma 63 | 3,232
Breast cancer 55 | 3,578
ependymoma 53 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,291
non-small cell lung cancer 52 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 50 | 2,989
lung adenocarcinoma 50 | 2,716
atypical teratoid / rhabdoid tumor 47 | 5,112
group 3 medulloblastoma 47 | 4,104
ulcerative colitis 46 | 1,819
invasive ductal carcinoma 45 | 2,951
pancreatic cancer 45 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,955
tuberculosis 43 | 2,010
lung carcinoma 42 | 2,843
interstitial cystitis 40 | 2,312
subependymal giant cell astrocytoma 40 | 2,287
oligodendroglioma 39 | 2,850
breast carcinoma 36 | 1,638
cystic fibrosis 36 | 1,696
Astrocytoma, Pilocytic 35 | 3,081
adult high grade glioma 35 | 3,801
pituitary cancer 35 | 1,972
astrocytic glioma 34 | 2,597
primitive neuroectodermal tumor 34 | 3,035
Prostatic Neoplasms 31 | 495
group 4 medulloblastoma 31 | 1,855
ductal carcinoma in situ 30 | 1,745
Breast Neoplasms 29 | 445
Mammary Neoplasms 29 | 425
Rheumatoid arthritis 28 | 1,191
colon cancer 28 | 1,478
diabetes mellitus 28 | 1,728
pediatric high grade glioma 28 | 1,064
Schizophrenia 27 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
cutaneous lupus erythematosus 26 | 1,057
Kidney cancer 25 | 2,613
adrenocortical carcinoma 25 | 1,428
acute myeloid leukemia 23 | 783
Autosomal recessive predisposition 22 | 1,442
Liver Cirrhosis, Experimental 21 | 769
Multiple myeloma 21 | 1,332
astrocytoma 21 | 1,146
Intellectual disability 20 | 1,016
primary pancreatic ductal adenocarcinoma 20 | 1,109
Carcinoma, Hepatocellular 19 | 228
Leukemia, Myelocytic, Acute 19 | 120
Liver carcinoma 19 | 240
Multiple Sclerosis 19 | 540
acute quadriplegic myopathy 19 | 1,158
juvenile dermatomyositis 19 | 1,187
Short stature 18 | 531
nasopharyngeal carcinoma 18 | 1,058
Alzheimer's disease 17 | 658
Bipolar Disorder 17 | 666
Dull intelligence 17 | 645
Leukemia, Myeloid, Acute 17 | 105
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Obesity 17 | 678
Pick disease 17 | 1,894
Poor school performance 17 | 645
Stomach Neoplasms 17 | 300
mucosa-associated lymphoid tissue lymphoma 17 | 484
spina bifida 17 | 1,074
Asthma 16 | 385
Cell Transformation, Neoplastic 16 | 97
Neoplastic Cell Transformation 16 | 89
Waldenstrons macroglobulinemia 16 | 765
dermatomyositis 16 | 966
primary Sjogren syndrome 16 | 735
Atopic dermatitis 15 | 952
Endometriosis 15 | 540
Kidney disease 15 | 430
Sarcoma 15 | 62
esophageal adenocarcinoma 15 | 737
Arthritis 14 | 290
Arthritis, Rheumatoid 14 | 174
Colonic Neoplasms 14 | 142
active ulcerative colitis 14 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
gastric carcinoma 14 | 807
non primary Sjogren syndrome sicca 14 | 891
Atherosclerosis 13 | 291
Bladder Neoplasm 13 | 112
Duchenne muscular dystrophy 13 | 601
Urinary Bladder Neoplasms 13 | 114
Vascular disease 13 | 319
active Crohn's disease 13 | 922
hepatocellular carcinoma 13 | 547

Tissue

Endocrine System 170 | 18,159
Male tissues 168 | 17,142
Digestive Tract 167 | 17,369
Female tissues 167 | 17,400
Skin and soft tissues 167 | 17,230
Blood and immune system 166 | 16,909
Liver and Pancreas 165 | 16,750
Urinary Tract 164 | 16,678
Nervous System 162 | 16,725
Respiratory system 162 | 16,393
Cardiovascular System 154 | 15,192

Target Family

Non-IDG 66 | 12,091
Transcription Factor 60 | 1,400
Enzyme 17 | 4,145
Kinase 12 | 634
Epigenetic 7 | 242
Nuclear Receptor 6 | 48
Ion Channel 1 | 344
TF/Epigenetic 1 | 38
Transporter 1 | 473

KEGG Pathway

Transcriptional misregulation ... 171 | 171
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Friend leukemia integration 1 transcription factor FLI1 Tbio Transcription Factor -1.82504 66.8 454
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
Prominin-1 PROM1 Tbio Non-IDG -3.30229 2035.0 351
NF-kappa-B inhibitor zeta NFKBIZ Tbio Non-IDG -2.14151 143.2 111
AF4/FMR2 family member 1 AFF1 Tbio Transcription Factor -2.60388 403.1 201