Development Level

Tbio 65 | 11,445
Tchem 49 | 1,598
Tclin 10 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased neutrophil cell numb... 4 | 46
decreased lymphocyte cell numb... 3 | 83
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
abnormal skin morphology 2 | 50
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
impaired glucose tolerance 2 | 75
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
absent testes 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased respiratory quotient 1 | 16
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged uterus 1 | 11
hyperactivity 1 | 148
increased basophil cell number 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 72 | 11,493
ovarian cancer 62 | 8,520
glioblastoma 59 | 5,792
Cancer 58 | 2,499
lung cancer 53 | 4,740
psoriasis 53 | 6,694
osteosarcoma 49 | 7,950
Rheumatoid arthritis 43 | 1,191
diabetes mellitus 40 | 1,728
lung carcinoma 38 | 2,843
atypical teratoid / rhabdoid tumor 36 | 5,112
tuberculosis 36 | 2,010
Astrocytoma, Pilocytic 35 | 3,081
medulloblastoma, large-cell 35 | 6,241
ependymoma 32 | 4,679
Breast cancer 31 | 3,578
Multiple Sclerosis 31 | 540
adult high grade glioma 31 | 3,801
invasive ductal carcinoma 30 | 2,951
ulcerative colitis 30 | 1,819
Schizophrenia 29 | 1,160
subependymal giant cell astrocytoma 29 | 2,287
malignant mesothelioma 26 | 3,232
Arthritis 25 | 290
Asthma 25 | 385
Kidney cancer 25 | 2,613
interstitial cystitis 25 | 2,312
pancreatic cancer 25 | 2,398
Hypersensitivity reaction type II disease 24 | 253
cystic fibrosis 24 | 1,696
sarcoidosis 24 | 370
non-small cell lung cancer 23 | 2,890
Autosomal recessive predisposition 22 | 1,442
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Inflammatory bowel disease 21 | 151
Vascular disease 21 | 319
breast carcinoma 21 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
Systemic lupus erythematosus 20 | 194
astrocytoma 20 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
juvenile dermatomyositis 19 | 1,187
dermatomyositis 18 | 966
group 4 medulloblastoma 18 | 1,855
lung adenocarcinoma 18 | 2,716
Berylliosis 17 | 28
Kidney disease 17 | 430
Narcolepsy 17 | 72
Reperfusion Injury 17 | 86
group 3 medulloblastoma 17 | 4,104
primary Sjogren syndrome 17 | 735
Arthritis, Rheumatoid 16 | 174
Brain Ischemia 16 | 110
Liver Cirrhosis, Experimental 16 | 769
Liver disease 16 | 237
active ulcerative colitis 16 | 764
oligodendroglioma 16 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Alzheimer's disease 15 | 658
Atherosclerosis 15 | 291
Breast Neoplasms 15 | 445
Crohn's disease 15 | 321
Mammary Neoplasms 15 | 425
cutaneous lupus erythematosus 15 | 1,057
follicular lymphoma 15 | 20
primary pancreatic ductal adenocarcinoma 15 | 1,109
Anemia 14 | 365
Lung disease 14 | 142
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Obesity 14 | 678
Prostatic Neoplasms 14 | 495
active Crohn's disease 14 | 922
ductal carcinoma in situ 14 | 1,745
esophageal adenocarcinoma 14 | 737
Bipolar Disorder 13 | 666
Coronary artery disease 13 | 268
Diffuse cutaneous systemic sclerosis 13 | 17
Duchenne muscular dystrophy 13 | 601
Fever 13 | 138
Heart disease 13 | 306
Immunologic Deficiency Syndromes 13 | 113
Lung Neoplasms 13 | 232
Multiple myeloma 13 | 1,332
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
adrenocortical carcinoma 13 | 1,428
limited scleroderma 13 | 19
pituitary cancer 13 | 1,972
Diabetes Mellitus, Type 2 12 | 142
Pneumonia 12 | 174
Vasculitis 12 | 80
colon cancer 12 | 1,478
Diabetes Mellitus, Non-Insulin-Dependent 11 | 145
Hepatitis B 11 | 108
Hypersensitivity 11 | 63
Hypertensive disease 11 | 292
Inflammation 11 | 120
Stomach Neoplasms 11 | 300
primitive neuroectodermal tumor 11 | 3,035

Tissue

Blood and immune system 109 | 16,909
Endocrine System 109 | 18,159
Respiratory system 109 | 16,393
Skin and soft tissues 109 | 17,230
Digestive Tract 108 | 17,369
Female tissues 108 | 17,400
Liver and Pancreas 108 | 16,750
Male tissues 108 | 17,142
Urinary Tract 108 | 16,678
Nervous System 104 | 16,725
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 83 | 12,091
Kinase 26 | 634
Enzyme 11 | 4,145
Transcription Factor 4 | 1,400
GPCR 1 | 408

KEGG Pathway

Toxoplasmosis 125 | 125
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
HLA class II histocompatibility antigen, DRB1-9 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0
Laminin subunit beta-4 LAMB4 Tbio Non-IDG -0.78478 6.19 13
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 489
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Tumor necrosis factor receptor superfamily member 5 CD40 Tchem Non-IDG -3.50040 3120.3 1879