Development Level

Tbio 44 | 11,651
Tchem 40 | 1,388
Tclin 15 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body weight 3 | 161
decreased circulating creatini... 3 | 39
decreased mean corpuscular vol... 3 | 79
preweaning lethality, incomple... 3 | 499
small superior vagus ganglion 3 | 74
abnormal gait 2 | 69
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased lymphocyte cell numb... 2 | 32
increased neutrophil cell numb... 2 | 46
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal skin condition 1 | 6
abnormal vibrissa morphology 1 | 25
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Cancer 68 | 2,499
Carcinoma 61 | 11,493
glioblastoma 53 | 5,792
psoriasis 53 | 6,694
ovarian cancer 51 | 8,520
lung cancer 43 | 4,740
osteosarcoma 35 | 7,950
adult high grade glioma 34 | 3,801
medulloblastoma, large-cell 34 | 6,241
tuberculosis 34 | 2,010
Arthritis 33 | 290
atypical teratoid / rhabdoid tumor 30 | 5,112
Influenza 29 | 142
Asthma 28 | 385
Astrocytoma, Pilocytic 28 | 3,081
Multiple Sclerosis 28 | 540
diabetes mellitus 28 | 1,728
lung carcinoma 27 | 2,843
malignant mesothelioma 25 | 3,232
Breast cancer 24 | 3,578
Hypersensitivity reaction type II disease 24 | 253
interstitial cystitis 24 | 2,312
Rheumatoid arthritis 23 | 1,191
Schizophrenia 23 | 1,160
Inflammatory bowel disease 22 | 151
cutaneous lupus erythematosus 22 | 1,057
Lung disease 21 | 142
ependymoma 21 | 4,679
ulcerative colitis 21 | 1,819
cystic fibrosis 20 | 1,696
invasive ductal carcinoma 20 | 2,951
Vascular disease 19 | 319
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
juvenile dermatomyositis 19 | 1,187
subependymal giant cell astrocytoma 19 | 2,287
Kidney disease 18 | 430
pancreatic cancer 18 | 2,398
Breast Neoplasms 17 | 445
Mammary Neoplasms 17 | 425
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung adenocarcinoma 17 | 2,716
non-small cell lung cancer 17 | 2,890
Lung Neoplasms 16 | 232
Obesity 16 | 678
Reperfusion Injury 16 | 86
Dermatitis 15 | 157
Kidney cancer 15 | 2,613
Liver disease 15 | 237
Malaria 15 | 160
Pneumonia 15 | 174
Allergic hypersensitivity disease 14 | 126
Atherosclerosis 14 | 291
Brain Ischemia 14 | 110
Human immunodeficiency virus infectious disease 14 | 138
Liver Cirrhosis, Experimental 14 | 769
Liver carcinoma 14 | 240
breast carcinoma 14 | 1,638
group 4 medulloblastoma 14 | 1,855
Autosomal recessive predisposition 13 | 1,442
Cholestasis, Extrahepatic 13 | 25
Hepatitis B 13 | 108
Hepatitis C 13 | 94
Seizures 13 | 596
Brain Injuries 12 | 65
Carcinoma, Hepatocellular 12 | 228
Depressive disorder 12 | 409
Inflammation 12 | 120
Meningitis 12 | 67
Neoplasm Metastasis 12 | 168
Prostatic Neoplasms 12 | 495
acute myeloid leukemia 12 | 783
dermatomyositis 12 | 966
group 3 medulloblastoma 12 | 4,104
hepatocellular carcinoma 12 | 547
Arthritis, Rheumatoid 11 | 174
Coronary artery disease 11 | 268
Diarrhea 11 | 253
Encephalitis 11 | 64
Epilepsy 11 | 792
Hypertension 11 | 396
Immunologic Deficiency Syndromes 11 | 113
Osteoporosis 11 | 363
Stomach Neoplasms 11 | 300
colon cancer 11 | 1,478
pancreatic carcinoma 11 | 562
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,035
Alzheimer's disease 10 | 658
Bipolar Disorder 10 | 666
Endometriosis 10 | 540
Heart disease 10 | 306
Leishmaniasis 10 | 47
Parkinson's disease 10 | 392
active Crohn's disease 10 | 922
astrocytoma 10 | 1,146
ductal carcinoma in situ 10 | 1,745
gastric cancer 10 | 459
nasopharyngeal carcinoma 10 | 1,058

Tissue

Blood and immune system 91 | 16,909
Male tissues 90 | 17,142
Urinary Tract 89 | 16,678
Digestive Tract 88 | 17,369
Endocrine System 88 | 18,159
Female tissues 88 | 17,400
Liver and Pancreas 88 | 16,750
Nervous System 88 | 16,725
Skin and soft tissues 88 | 17,230
Respiratory system 87 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 54 | 12,091
Kinase 33 | 634
Transcription Factor 8 | 1,400
Enzyme 6 | 4,145

KEGG Pathway

Toll-like receptor signaling p... 101 | 101
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.28820 202.2 610
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
Dual specificity mitogen-activated protein kinase kinase 6 MAP2K6 Tchem Kinase -2.01763 74.4 636
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Mitogen-activated protein kinase 12 MAPK12 Tchem Kinase -1.95173 88.4 378
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384