Development Level

Tchem 48 | 1,890
Tbio 38 | 10,625
Tclin 14 | 602
Tdark 3 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
decreased body weight 3 | 174
decreased circulating creatini... 3 | 31
decreased lean body mass 3 | 195
decreased KLRG1+ CD8 alpha bet... 2 | 8
decreased Ly6C low monocyte nu... 2 | 23
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased mean corpuscular vol... 2 | 50
decreased monocyte cell number 2 | 28
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased NK cell number 2 | 19
increased circulating alkaline... 2 | 119
increased erythrocyte cell num... 2 | 26
small superior vagus ganglion 2 | 20
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal skin condition 1 | 6
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased CD5-positive Ly6C-po... 1 | 4
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased thermal nociceptive ... 1 | 4
enlarged lymph nodes 1 | 27
increased B cell number 1 | 23
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased thermal nociceptive ... 1 | 9
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
thrombocytosis 1 | 23
vertebral fusion 1 | 23

Disease

Cancer 66 | 2,346
psoriasis 53 | 6,685
ovarian cancer 51 | 8,484
glioblastoma 49 | 5,572
lung cancer 42 | 4,466
osteosarcoma 37 | 7,933
medulloblastoma, large-cell 34 | 6,234
tuberculosis 32 | 1,557
Influenza 29 | 142
lung carcinoma 29 | 2,844
pilocytic astrocytoma 29 | 3,086
Arthritis 28 | 248
Multiple Sclerosis 28 | 498
atypical teratoid / rhabdoid tumor 28 | 4,369
ulcerative colitis 28 | 2,087
Asthma 27 | 349
diabetes mellitus 26 | 1,663
interstitial cystitis 26 | 2,299
Rheumatoid Arthritis 23 | 1,160
cutaneous lupus erythematosus 22 | 1,056
invasive ductal carcinoma 22 | 2,950
malignant mesothelioma 22 | 3,162
Hypersensitivity reaction type II disease 21 | 235
subependymal giant cell astrocytoma 21 | 2,287
Lung disease 20 | 132
adult high grade glioma 20 | 2,148
Breast cancer 19 | 3,094
Inflammatory bowel disease 19 | 142
cystic fibrosis 19 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
juvenile dermatomyositis 19 | 1,189
non-small cell lung cancer 19 | 2,798
pediatric high grade glioma 19 | 2,712
Vascular disease 18 | 281
Kidney disease 17 | 396
Mammary Neoplasms 17 | 410
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
lung adenocarcinoma 17 | 2,713
pancreatic cancer 17 | 2,300
Lung Neoplasms 16 | 171
Reperfusion Injury 16 | 84
Carcinoma 15 | 2,147
Brain Ischemia 14 | 87
Dermatitis 14 | 107
Hepatitis B 14 | 103
Liver disease 14 | 219
Obesity 14 | 616
posterior fossa group A ependymoma 14 | 1,511
primary Sjogren syndrome 14 | 789
Atherosclerosis 13 | 275
Pneumonia 13 | 133
medulloblastoma 13 | 1,524
Allergic hypersensitivity disease 12 | 123
Hepatitis C 12 | 90
Human immunodeficiency virus infectious disease 12 | 92
Inflammation 12 | 109
Malaria 12 | 140
Prostatic Neoplasms 12 | 471
acute myeloid leukemia 12 | 780
breast carcinoma 12 | 1,614
dermatomyositis 12 | 933
group 4 medulloblastoma 12 | 1,875
Meningitis 11 | 46
Toxic encephalopathy 11 | 131
colon cancer 11 | 1,475
ependymoma 11 | 2,514
pancreatic carcinoma 11 | 567
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,031
Alzheimer's disease 10 | 644
Coronary artery disease 10 | 240
Encephalitis 10 | 54
Heart disease 10 | 279
IGA Glomerulonephritis 10 | 454
Liver carcinoma 10 | 217
Neoplasm Metastasis 10 | 138
Osteoporosis 10 | 257
Stomach Neoplasms 10 | 282
active Crohn's disease 10 | 918
astrocytoma 10 | 1,493
ductal carcinoma in situ 10 | 1,745
gastric carcinoma 10 | 832
hepatocellular carcinoma 10 | 532
nasopharyngeal carcinoma 10 | 1,056
periodontitis 10 | 269
sarcoidosis 10 | 358
Endometriosis 9 | 535
Eye disease 9 | 55
Leishmaniasis 9 | 49
Multiple myeloma 9 | 1,327
Myocardial Ischemia 9 | 169
Parkinson's disease 9 | 364
Peritonitis 9 | 37
Pick disease 9 | 1,893
Schizophrenia 9 | 501
gastric cancer 9 | 430
mucosa-associated lymphoid tissue lymphoma 9 | 480
oligodendroglioma 9 | 2,849

Tissue

Nervous System 98 | 18,561
Digestive Tract 96 | 18,473
Female tissues 96 | 18,647
Urinary Tract 96 | 18,444
Blood and immune system 93 | 17,995
Skin and soft tissues 92 | 18,115
Endocrine System 91 | 18,512
Liver and Pancreas 90 | 18,136
Cardiovascular System 89 | 17,958
Respiratory system 87 | 17,484
Male tissues 85 | 17,969

Target Family

Non-IDG 54 | 11,971
Kinase 34 | 634
Transcription Factor 8 | 1,400
Enzyme 7 | 4,146

KEGG Pathway

Toll-like receptor signaling p... 103 | 103
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.83055 69.0 145
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.87993 74.0 225
C-X-C motif chemokine 9 CXCL9 Tbio Non-IDG -2.88793 860.6 317