Development Level

Tbio 122 | 11,445
Tchem 30 | 1,598
Tdark 9 | 6,588
Tclin 8 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 12 | 499
abnormal retina morphology 8 | 71
increased or absent threshold ... 5 | 101
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
decreased lean body mass 4 | 135
decreased startle reflex 4 | 75
decreased total body fat amoun... 4 | 207
abnormal embryo size 3 | 220
absent startle reflex 3 | 24
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular vol... 3 | 79
decreased prepulse inhibition 3 | 82
edema 3 | 59
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased circulating alkaline... 3 | 122
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
abnormal craniofacial morpholo... 2 | 33
abnormal neural tube closure 2 | 46
abnormal pericardium morpholog... 2 | 26
abnormal placenta size 2 | 20
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased exploration in new e... 2 | 11
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean platelet volume 2 | 25
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
enlarged spleen 2 | 41
female infertility 2 | 60
hemorrhage 2 | 23
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased bone mineral content 2 | 108
increased erythrocyte cell num... 2 | 39
increased hematocrit 2 | 46
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged thymus 1 | 5
hyperactivity 1 | 148
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
prenatal lethality 1 | 28
short tibia 1 | 97

Disease

Carcinoma 127 | 11,493
ovarian cancer 99 | 8,520
psoriasis 79 | 6,694
osteosarcoma 77 | 7,950
medulloblastoma, large-cell 72 | 6,241
glioblastoma 70 | 5,792
atypical teratoid / rhabdoid tumor 65 | 5,112
ependymoma 57 | 4,679
Cancer 54 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,989
lung cancer 52 | 4,740
Breast cancer 48 | 3,578
adult high grade glioma 48 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,291
Kidney cancer 46 | 2,613
lung adenocarcinoma 45 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,955
non-small cell lung cancer 41 | 2,890
group 3 medulloblastoma 40 | 4,104
malignant mesothelioma 39 | 3,232
invasive ductal carcinoma 38 | 2,951
pancreatic cancer 37 | 2,398
Astrocytoma, Pilocytic 36 | 3,081
primitive neuroectodermal tumor 36 | 3,035
subependymal giant cell astrocytoma 35 | 2,287
ductal carcinoma in situ 33 | 1,745
astrocytic glioma 32 | 2,597
oligodendroglioma 32 | 2,850
interstitial cystitis 30 | 2,312
lung carcinoma 30 | 2,843
breast carcinoma 25 | 1,638
pituitary cancer 24 | 1,972
spina bifida 24 | 1,074
group 4 medulloblastoma 23 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
cystic fibrosis 22 | 1,696
Pick disease 21 | 1,894
colon cancer 21 | 1,478
Schizophrenia 20 | 1,160
diabetes mellitus 20 | 1,728
primary pancreatic ductal adenocarcinoma 20 | 1,109
acute quadriplegic myopathy 19 | 1,158
Autosomal recessive predisposition 17 | 1,442
Duchenne muscular dystrophy 17 | 601
Melanoma 17 | 711
astrocytoma 17 | 1,146
ulcerative colitis 17 | 1,819
Multiple myeloma 16 | 1,332
juvenile dermatomyositis 16 | 1,187
cutaneous lupus erythematosus 15 | 1,057
Bipolar Disorder 14 | 666
Prostatic Neoplasms 14 | 495
adrenocortical carcinoma 14 | 1,428
pediatric high grade glioma 14 | 1,064
tuberculosis 14 | 2,010
Down syndrome 13 | 499
Rheumatoid arthritis 13 | 1,191
Skin cancer 13 | 469
Stomach Neoplasms 13 | 300
Breast Neoplasms 12 | 445
Kidney disease 12 | 430
Waldenstrons macroglobulinemia 12 | 765
dermatomyositis 12 | 966
nasopharyngeal carcinoma 12 | 1,058
Amyotrophic lateral sclerosis 11 | 451
Vascular disease 11 | 319
active Crohn's disease 11 | 922
acute myeloid leukemia 11 | 783
aldosterone-producing adenoma 11 | 665
primary Sjogren syndrome 11 | 735
Epilepsy 10 | 792
Mammary Neoplasms 10 | 425
Osteoporosis 10 | 363
Parkinson's disease 10 | 392
active ulcerative colitis 10 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
gastric carcinoma 10 | 807
medulloblastoma 10 | 720
Endometrial cancer 9 | 311
Heart disease 9 | 306
Hypertension 9 | 396
Intellectual disability 9 | 1,016
Mammary Neoplasms, Experimental 9 | 154
Neurodegenerative disease 9 | 414
esophageal adenocarcinoma 9 | 737
fibroadenoma 9 | 559
Animal Mammary Neoplasms 8 | 136
Asthma 8 | 385
Inflammatory bowel disease 8 | 151
Lung Neoplasms 8 | 232
Mammary Neoplasms, Animal 8 | 136
Seizures 8 | 596
hereditary spastic paraplegia 8 | 318
interstitial lung disease 8 | 298
non primary Sjogren syndrome sicca 8 | 891
pancreatic carcinoma 8 | 562
Becker muscular dystrophy 7 | 191
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608

Tissue

Endocrine System 167 | 18,159
Digestive Tract 165 | 17,369
Skin and soft tissues 164 | 17,230
Female tissues 162 | 17,400
Male tissues 162 | 17,142
Blood and immune system 158 | 16,909
Liver and Pancreas 157 | 16,750
Urinary Tract 157 | 16,678
Nervous System 154 | 16,725
Respiratory system 154 | 16,393
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 117 | 12,091
Enzyme 23 | 4,145
Kinase 22 | 634
Transcription Factor 4 | 1,400
Ion Channel 2 | 344
Transporter 1 | 473

KEGG Pathway

Tight junction 169 | 169
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
Myosin-15 MYH15 Tbio Non-IDG -0.95780 9.01 40