Development Level

Tbio 117 | 10,625
Tchem 35 | 1,890
Tdark 9 | 7,003
Tclin 8 | 602

Collection

Eligible Kinase Proteins 4 | 134

IMPC Term

preweaning lethality, incomple... 9 | 260
preweaning lethality, complete... 7 | 633
abnormal retina morphology 6 | 100
decreased total body fat amoun... 6 | 186
decreased lean body mass 5 | 195
increased or absent threshold ... 5 | 128
abnormal retinal pigmentation 4 | 61
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
absent startle reflex 3 | 15
decreased startle reflex 3 | 48
increased erythrocyte cell num... 3 | 26
abnormal bone structure 2 | 131
abnormal eye morphology 2 | 38
abnormal neural tube closure 2 | 37
abnormal placenta size 2 | 10
abnormal sleep behavior 2 | 63
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased exploration in new e... 2 | 9
decreased fasted circulating g... 2 | 49
decreased hematocrit 2 | 25
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
enlarged spleen 2 | 26
female infertility 2 | 34
hemorrhage 2 | 12
hydrops fetalis 2 | 22
immune system phenotype 2 | 17
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased hematocrit 2 | 36
male infertility 2 | 62
prenatal lethality prior to he... 2 | 64
shortened RR interval 2 | 19
abnormal behavioral response t... 1 | 52
abnormal craniofacial morpholo... 1 | 12
abnormal ear morphology 1 | 5
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 20
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
convulsive seizures 1 | 11
craniofacial phenotype 1 | 9
cyanosis 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
edema 1 | 11
hypoactivity 1 | 89
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased memory-marker gamma-... 1 | 2
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
shortened PQ interval 1 | 6
thrombocytopenia 1 | 46

Disease

ovarian cancer 98 | 8,484
psoriasis 79 | 6,685
osteosarcoma 77 | 7,933
medulloblastoma, large-cell 72 | 6,234
glioblastoma 69 | 5,572
atypical teratoid / rhabdoid tumor 59 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,988
lung cancer 52 | 4,466
Cancer 48 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,289
lung adenocarcinoma 46 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,956
malignant mesothelioma 39 | 3,162
non-small cell lung cancer 39 | 2,798
invasive ductal carcinoma 38 | 2,950
Breast cancer 37 | 3,094
Carcinoma 37 | 2,147
pancreatic cancer 37 | 2,300
primitive neuroectodermal tumor 36 | 3,031
pilocytic astrocytoma 35 | 3,086
subependymal giant cell astrocytoma 35 | 2,287
pediatric high grade glioma 34 | 2,712
ductal carcinoma in situ 33 | 1,745
ependymoma 33 | 2,514
oligodendroglioma 32 | 2,849
lung carcinoma 30 | 2,844
interstitial cystitis 29 | 2,299
adult high grade glioma 28 | 2,148
astrocytic glioma 27 | 2,241
group 4 medulloblastoma 25 | 1,875
breast carcinoma 24 | 1,614
medulloblastoma 24 | 1,524
pituitary cancer 24 | 1,972
spina bifida 24 | 1,064
primary pancreatic ductal adenocarcinoma 23 | 1,271
astrocytoma 22 | 1,493
cystic fibrosis 22 | 1,665
ulcerative colitis 22 | 2,087
Pick disease 21 | 1,893
colon cancer 21 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Down syndrome 19 | 548
acute quadriplegic myopathy 19 | 1,157
diabetes mellitus 19 | 1,663
Duchenne muscular dystrophy 17 | 602
Multiple myeloma 16 | 1,327
juvenile dermatomyositis 16 | 1,189
cutaneous lupus erythematosus 15 | 1,056
posterior fossa group A ependymoma 15 | 1,511
posterior fossa group B ependymoma 15 | 1,530
adrenocortical carcinoma 14 | 1,427
group 3 medulloblastoma 14 | 2,254
Prostatic Neoplasms 13 | 471
Rheumatoid Arthritis 13 | 1,160
Stomach Neoplasms 12 | 282
Waldenstrons macroglobulinemia 12 | 765
dermatomyositis 12 | 933
nasopharyngeal carcinoma 12 | 1,056
Amyotrophic Lateral Sclerosis 11 | 431
Kidney disease 11 | 396
Vascular disease 11 | 281
active Crohn's disease 11 | 918
acute myeloid leukemia 11 | 780
aldosterone-producing adenoma 11 | 664
gastric carcinoma 11 | 832
primary Sjogren syndrome 11 | 789
Mammary Neoplasms 10 | 410
Parkinson's disease 10 | 364
sonic hedgehog group medulloblastoma 10 | 1,482
Mammary Neoplasms, Experimental 9 | 150
atypical teratoid/rhabdoid tumor 9 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
esophageal adenocarcinoma 9 | 737
fibroadenoma 9 | 557
pancreatic carcinoma 9 | 567
tuberculosis 9 | 1,557
Animal Mammary Neoplasms 8 | 136
Heart disease 8 | 279
Lung Neoplasms 8 | 171
Neurodegenerative disease 8 | 383
hereditary spastic paraplegia 8 | 313
interstitial lung disease 8 | 291
non primary Sjogren syndrome sicca 8 | 840
Atopic dermatitis 7 | 944
Becker muscular dystrophy 7 | 187
Chronic Lymphocytic Leukemia 7 | 242
Hypertension 7 | 287
IGA Glomerulonephritis 7 | 454
Intellectual disability 7 | 573
Muscle Weakness 7 | 92
Myocardial Ischemia 7 | 169
Neoplastic Cell Transformation 7 | 81
tuberculosis and treatment for 3 months 7 | 327
Endometriosis 6 | 535
Inflammatory bowel disease 6 | 142
Multiple Sclerosis 6 | 498
Schizophrenia 6 | 501
inflammatory breast cancer 6 | 404
mucosa-associated lymphoid tissue lymphoma 6 | 480
progressive supranuclear palsy 6 | 674

Tissue

Digestive Tract 168 | 18,473
Endocrine System 168 | 18,512
Female tissues 168 | 18,647
Nervous System 168 | 18,561
Skin and soft tissues 168 | 18,115
Liver and Pancreas 167 | 18,136
Urinary Tract 167 | 18,444
Blood and immune system 166 | 17,995
Cardiovascular System 166 | 17,958
Respiratory system 166 | 17,484
Male tissues 165 | 17,969

Target Family

Non-IDG 117 | 11,971
Enzyme 23 | 4,146
Kinase 22 | 634
Transcription Factor 4 | 1,400
Ion Channel 2 | 341
Transporter 1 | 473

KEGG Pathway

Tight junction 169 | 169
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Myosin light chain 6B MYL6B Tdark Non-IDG -0.43175 2.57 113
Actin-related protein 2 ACTR2 Tchem Non-IDG -1.84526 72.5 184
Actin-related protein 3 ACTR3 Tbio Non-IDG -1.25542 16.8 169
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.35800 26.2 55
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A Tchem Enzyme -1.29353 14.5 115
Blood vessel epicardial substance BVES Tbio Non-IDG -1.46376 36.1 156
Radixin RDX Tbio Non-IDG -2.45592 216.9 310
Merlin NF2 Tbio Non-IDG -3.13004 1456.9 431
InaD-like protein PATJ Tbio Non-IDG -1.88739 77.1 91