Development Level

Tbio 56 | 11,651
Tchem 37 | 1,388
Tclin 25 | 612
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

male infertility 4 | 123
abnormal heart morphology 2 | 162
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
increased bone mineral density 2 | 72
increased erythrocyte cell num... 2 | 39
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged testis 1 | 6
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased thermal nociceptive ... 1 | 9
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Carcinoma 70 | 11,493
Cancer 63 | 2,499
psoriasis 56 | 6,694
osteosarcoma 55 | 7,950
Rheumatoid arthritis 54 | 1,191
ovarian cancer 53 | 8,520
lung cancer 49 | 4,740
glioblastoma 46 | 5,792
lung carcinoma 39 | 2,843
medulloblastoma, large-cell 37 | 6,241
diabetes mellitus 35 | 1,728
interstitial cystitis 33 | 2,312
malignant mesothelioma 32 | 3,232
Astrocytoma, Pilocytic 30 | 3,081
Multiple Sclerosis 30 | 540
tuberculosis 30 | 2,010
adult high grade glioma 29 | 3,801
ependymoma 29 | 4,679
Asthma 28 | 385
subependymal giant cell astrocytoma 28 | 2,287
Breast cancer 27 | 3,578
Hypersensitivity reaction type II disease 27 | 253
Schizophrenia 27 | 1,160
invasive ductal carcinoma 27 | 2,951
ulcerative colitis 25 | 1,819
Arthritis 24 | 290
atypical teratoid / rhabdoid tumor 24 | 5,112
pancreatic cancer 24 | 2,398
lung adenocarcinoma 23 | 2,716
non-small cell lung cancer 23 | 2,890
sarcoidosis 23 | 370
Inflammatory bowel disease 22 | 151
Arthritis, Rheumatoid 20 | 174
cutaneous lupus erythematosus 20 | 1,057
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
breast carcinoma 19 | 1,638
group 4 medulloblastoma 19 | 1,855
Berylliosis 18 | 28
Kidney cancer 18 | 2,613
Pneumonia 18 | 174
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Autosomal recessive predisposition 17 | 1,442
Narcolepsy 17 | 72
Systemic lupus erythematosus 17 | 194
Waldenstrons macroglobulinemia 17 | 765
group 3 medulloblastoma 17 | 4,104
oligodendroglioma 17 | 2,850
pituitary cancer 17 | 1,972
Immunologic Deficiency Syndromes 16 | 113
Kidney disease 16 | 430
astrocytoma 16 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
juvenile dermatomyositis 16 | 1,187
Bipolar Disorder 15 | 666
Brain Ischemia 15 | 110
Breast Neoplasms 15 | 445
Dermatitis 15 | 157
Lung disease 15 | 142
Mammary Neoplasms 15 | 425
Vascular disease 15 | 319
primitive neuroectodermal tumor 15 | 3,035
Crohn's disease 14 | 321
Hypersensitivity 14 | 63
Hypertensive disease 14 | 292
Juvenile rheumatoid arthritis 14 | 111
Liver Cirrhosis, Experimental 14 | 769
Liver disease 14 | 237
Multiple Sclerosis, Susceptibility to 14 | 15
Multiple myeloma 14 | 1,332
Narcolepsy-cataplexy 14 | 21
Rheumatoid Arthritis, Systemic Juvenile 14 | 16
Type 1 diabetes mellitus 14 | 109
acute quadriplegic myopathy 14 | 1,158
dermatomyositis 14 | 966
ductal carcinoma in situ 14 | 1,745
primary Sjogren syndrome 14 | 735
Diffuse cutaneous systemic sclerosis 13 | 17
Hepatitis B 13 | 108
Lung Neoplasms 13 | 232
Prostatic Neoplasms 13 | 495
Sarcoidosis 1 13 | 14
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
Anemia 12 | 365
Candidiasis 12 | 55
Inflammation 12 | 120
Major Depressive Disorder 12 | 301
Stomach Neoplasms 12 | 300
active Crohn's disease 12 | 922
active ulcerative colitis 12 | 764
colon cancer 12 | 1,478
cystic fibrosis 12 | 1,696
Allergic hypersensitivity disease 11 | 126
Depressive disorder 11 | 409
Pick disease 11 | 1,894
adrenocortical carcinoma 11 | 1,428
astrocytic glioma 11 | 2,597
esophageal adenocarcinoma 11 | 737
periodontitis 11 | 293

Tissue

Blood and immune system 103 | 16,909
Digestive Tract 102 | 17,369
Endocrine System 101 | 18,159
Skin and soft tissues 101 | 17,230
Urinary Tract 101 | 16,678
Liver and Pancreas 100 | 16,750
Male tissues 100 | 17,142
Respiratory system 99 | 16,393
Female tissues 98 | 17,400
Cardiovascular System 95 | 15,192
Nervous System 92 | 16,725

Target Family

Non-IDG 65 | 12,091
Kinase 22 | 634
Transcription Factor 22 | 1,400
Nuclear Receptor 6 | 48
Enzyme 4 | 4,145

KEGG Pathway

Th17 cell differentiation 119 | 119
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.61157 386.3 882
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555
Tyrosine-protein kinase JAK3 JAK3 Tclin Kinase -2.64385 453.7 292
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Interferon gamma receptor 1 IFNGR1 Tbio Non-IDG -2.23009 172.7 518
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Interleukin-2 receptor subunit beta IL2RB Tclin Non-IDG -2.17998 125.4 654