Development Level

Tbio 32 | 10,625
Tclin 24 | 602
Tchem 23 | 1,890
Tdark 4 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 24 | 143
Eligible Ion Channel Proteins 8 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal behavior 2 | 226
abnormal behavioral response t... 2 | 52
preweaning lethality, incomple... 2 | 260
abnormal lens morphology 1 | 73
abnormal pelvic girdle bone mo... 1 | 11
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased total body fat amoun... 1 | 57
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
short tail 1 | 4
small kidney 1 | 10
small superior vagus ganglion 1 | 20

Disease

psoriasis 26 | 6,685
medulloblastoma, large-cell 24 | 6,234
osteosarcoma 21 | 7,933
Carcinoma 19 | 2,147
Autistic Disorder 16 | 320
glioblastoma 16 | 5,572
Epilepsy 15 | 346
atypical teratoid / rhabdoid tumor 14 | 4,369
oligodendroglioma 14 | 2,849
primitive neuroectodermal tumor 14 | 3,031
ovarian cancer 13 | 8,484
pilocytic astrocytoma 13 | 3,086
subependymal giant cell astrocytoma 13 | 2,287
lung cancer 12 | 4,466
Irritable bowel syndrome 11 | 59
Schizophrenia 11 | 501
ependymoma 11 | 2,514
interstitial cystitis 11 | 2,299
malignant mesothelioma 11 | 3,162
lung carcinoma 10 | 2,844
pediatric high grade glioma 10 | 2,712
Pick disease 9 | 1,893
Status Epilepticus 9 | 85
Tonic-clonic epilepsy 9 | 47
lung adenocarcinoma 9 | 2,713
Alcohol dependence 8 | 107
Breast cancer 8 | 3,094
Migraine 8 | 79
adult high grade glioma 8 | 2,148
astrocytic glioma 8 | 2,241
diabetes mellitus 8 | 1,663
pituitary cancer 8 | 1,972
posterior fossa group A ependymoma 8 | 1,511
Atrial Fibrillation 7 | 110
General anesthesia 7 | 53
Local anesthesia 7 | 40
Parkinson's disease 7 | 364
cystic fibrosis 7 | 1,665
Anxiety 6 | 24
Benzodiazepine Induced Sedation 6 | 8
Benzodiazepine Maintained Anesthesia 6 | 8
Benzodiazepine Toxicity 6 | 8
Gastrointestinal Radiography Adjunct 6 | 11
Insomnia 6 | 20
Major Depressive Disorder 6 | 106
Nicotine dependence 6 | 53
Sedation as Adjunct to Anesthesia 6 | 15
astrocytoma 6 | 1,493
colon cancer 6 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
sonic hedgehog group medulloblastoma 6 | 1,482
Bipolar disorder in remission 5 | 19
Chemotherapy-induced nausea and vomiting 5 | 18
Diabetic gastroparesis 5 | 7
Dysuria 5 | 24
Gastroesophageal reflux disease 5 | 37
Generalized anxiety disorder 5 | 29
Hypertensive disease 5 | 193
Intubation of gastrointestinal tract 5 | 7
Pain agnosia 5 | 99
Panic disorder 5 | 55
Partial Epilepsy Treatment Adjunct 5 | 16
Pelvic inflammatory disease 5 | 21
Peptic ulcer 5 | 22
Prevention of Post-Operative Nausea and Vomiting 5 | 14
Spasticity 5 | 26
Urinary Tract Irritation 5 | 24
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
medulloblastoma 5 | 1,524
ulcerative colitis 5 | 2,087
Alcohol withdrawal delirium 4 | 9
Alcohol withdrawal syndrome 4 | 9
Alcoholic Intoxication, Chronic 4 | 41
Alzheimer's disease 4 | 644
Bipolar Disorder 4 | 266
Cocaine-Related Disorders 4 | 88
Cough 4 | 21
Epilepsy characterized by intractable complex partial seizures 4 | 28
Hypertension 4 | 287
Hypertensive disorder 4 | 58
Induce Anterograde Amnesia 4 | 9
Lennox-Gastaut syndrome 4 | 34
Liddle syndrome 4 | 14
Localization-related epilepsy 4 | 13
Obesity 4 | 616
Premature ejaculation 4 | 16
Preoperative Anxiety 4 | 9
Pseudohypoaldosteronism 4 | 22
Sedation 4 | 11
Seizures 4 | 95
Simple partial seizure 4 | 26
Tetanus 4 | 66
Tonic-clonic seizure 4 | 11
active Crohn's disease 4 | 918
atypical teratoid/rhabdoid tumor 4 | 1,095
pancreatic cancer 4 | 2,300

Tissue

Female tissues 81 | 18,647
Urinary Tract 81 | 18,444
Nervous System 80 | 18,561
Digestive Tract 78 | 18,473
Endocrine System 78 | 18,512
Skin and soft tissues 73 | 18,115
Blood and immune system 72 | 17,995
Liver and Pancreas 72 | 18,136
Cardiovascular System 71 | 17,958
Male tissues 69 | 17,969
Respiratory system 68 | 17,484

Target Family

GPCR 39 | 406
Ion Channel 29 | 341
Enzyme 8 | 4,146
Non-IDG 4 | 11,971
Kinase 3 | 634

KEGG Pathway

Taste transduction 83 | 83
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.19758 165.4 232
Taste receptor type 1 member 1 TAS1R1 Tbio GPCR -1.71516 50.8 165
Calcium homeostasis modulator protein 1 CALHM1 Tbio Ion Channel -1.62156 47.0 81
Amiloride-sensitive sodium channel subunit beta SCNN1B Tclin Ion Channel -1.69464 46.7 245
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.03787 117.0 162
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
Taste receptor type 2 member 42 TAS2R42 Tdark GPCR 0.11 0.69 13
Taste receptor type 2 member 4 TAS2R4 Tchem GPCR -1.19643 16.4 23
Taste receptor type 2 member 3 TAS2R3 Tbio GPCR -0.48474 3.19 77