Development Level

Tchem 59 | 1,890
Tbio 44 | 10,625
Tclin 7 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 5 | 633
decreased circulating creatini... 4 | 31
increased circulating alkaline... 4 | 119
decreased grip strength 3 | 123
decreased lean body mass 3 | 195
embryonic lethality prior to t... 3 | 187
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal neural tube closure 2 | 37
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased heart weight 2 | 44
hypoactivity 2 | 89
increased erythrocyte cell num... 2 | 26
increased leukocyte cell numbe... 2 | 37
short tibia 2 | 82
small superior vagus ganglion 2 | 20
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal glucose homeostasis 1 | 5
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal respiratory quotient 1 | 9
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 14
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
enlarged heart 1 | 111
increased circulating LDL chol... 1 | 15
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
thrombocytosis 1 | 23
tremors 1 | 34

Disease

Cancer 80 | 2,346
psoriasis 68 | 6,685
ovarian cancer 66 | 8,492
lung cancer 60 | 4,473
glioblastoma 57 | 5,572
osteosarcoma 46 | 7,933
ulcerative colitis 40 | 2,087
lung carcinoma 38 | 2,844
medulloblastoma, large-cell 38 | 6,234
atypical teratoid / rhabdoid tumor 37 | 4,369
malignant mesothelioma 36 | 3,163
interstitial cystitis 35 | 2,299
non-small cell lung cancer 35 | 2,798
Arthritis 30 | 248
cystic fibrosis 29 | 1,670
diabetes mellitus 29 | 1,663
tuberculosis 29 | 1,563
pilocytic astrocytoma 28 | 3,086
posterior fossa group A ependymoma 28 | 1,511
Breast cancer 26 | 3,099
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
lung adenocarcinoma 26 | 2,714
subependymal giant cell astrocytoma 25 | 2,287
Mammary Neoplasms 24 | 410
Lung disease 23 | 136
Rheumatoid Arthritis 23 | 1,171
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
pancreatic cancer 23 | 2,300
pediatric high grade glioma 23 | 2,712
Asthma 22 | 349
Kidney disease 22 | 397
Multiple Sclerosis 22 | 498
Obesity 22 | 616
invasive ductal carcinoma 22 | 2,950
Brain Ischemia 21 | 87
Inflammatory bowel disease 21 | 142
Vascular disease 21 | 281
cutaneous lupus erythematosus 20 | 1,056
pituitary cancer 20 | 1,972
primitive neuroectodermal tumor 20 | 3,031
Hypersensitivity reaction type II disease 19 | 235
Lung Neoplasms 19 | 171
adult high grade glioma 19 | 2,148
group 4 medulloblastoma 19 | 1,875
Reperfusion Injury 18 | 84
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
Atherosclerosis 17 | 275
Myocardial Ischemia 17 | 169
colon cancer 17 | 1,475
juvenile dermatomyositis 17 | 1,189
Alzheimer's disease 16 | 644
acute myeloid leukemia 16 | 785
Coronary artery disease 15 | 240
active Crohn's disease 15 | 918
astrocytoma 15 | 1,493
ependymoma 15 | 2,514
gastric carcinoma 15 | 832
primary Sjogren syndrome 15 | 789
Cerebrovascular disease 14 | 231
Dermatitis 14 | 141
Diabetes Mellitus, Experimental 14 | 106
Heart disease 14 | 279
Toxic encephalopathy 14 | 131
esophageal adenocarcinoma 14 | 737
Carcinoma 13 | 2,147
Endometriosis 13 | 535
Liver disease 13 | 219
Parkinson's disease 13 | 364
adrenocortical carcinoma 13 | 1,427
breast carcinoma 13 | 1,614
medulloblastoma 13 | 1,524
nasopharyngeal carcinoma 13 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
primary pancreatic ductal adenocarcinoma 13 | 1,271
spina bifida 13 | 1,064
Bipolar Disorder 12 | 266
Cardiomyopathies 12 | 90
Diabetes Mellitus, Non-Insulin-Dependent 12 | 161
Hyperglycemia 12 | 120
Hypertension 12 | 293
Pick disease 12 | 1,893
Prostatic Neoplasms 12 | 471
Schizophrenia 12 | 503
Stomach Neoplasms 12 | 282
oligodendroglioma 12 | 2,849
periodontitis 12 | 269
Colonic Neoplasms 11 | 126
Hypersensitivity 11 | 63
Inflammation 11 | 109
Liver carcinoma 11 | 217
Metabolic syndrome X 11 | 155
Peripheral Neuropathy 11 | 303
Pneumonia 11 | 133
dermatomyositis 11 | 967
head and neck cancer 11 | 270
Crohn's disease 10 | 304
Multiple myeloma 10 | 1,328
aldosterone-producing adenoma 10 | 664
ductal carcinoma in situ 10 | 1,745
hepatocellular carcinoma 10 | 550

Tissue

Blood and immune system 110 | 17,995
Cardiovascular System 109 | 17,958
Digestive Tract 109 | 18,473
Endocrine System 109 | 18,512
Female tissues 109 | 18,647
Liver and Pancreas 109 | 18,136
Nervous System 109 | 18,561
Respiratory system 109 | 17,484
Urinary Tract 109 | 18,444
Male tissues 108 | 17,969
Skin and soft tissues 108 | 18,115

Target Family

Non-IDG 45 | 11,969
Kinase 35 | 634
Transcription Factor 16 | 1,400
Enzyme 14 | 4,146

KEGG Pathway

TNF signaling pathway 110 | 110
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase kinase kinase 5 MAP3K5 Tchem Kinase -2.61089 467.7 1104
Baculoviral IAP repeat-containing protein 3 BIRC3 Tchem Non-IDG -2.60501 360.4 372
Interleukin-18 receptor 1 IL18R1 Tbio Non-IDG -1.47717 28.0 429
Baculoviral IAP repeat-containing protein 2 BIRC2 Tchem Non-IDG -2.51198 295.0 303
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.11206 1371.9 332
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.04744 808.6 1868
Caspase-8 CASP8 Tchem Enzyme -3.51864 2954.7 930
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.62805 3186.8 1232
Receptor-interacting serine/threonine-protein kinase 3 RIPK3 Tchem Kinase -2.11581 129.5 456