Development Level

Tbio 48 | 10,625
Tchem 7 | 1,890
Tdark 6 | 7,003
Tclin 2 | 602

IMPC Term

embryonic lethality prior to t... 8 | 187
embryonic lethality prior to o... 7 | 148
preweaning lethality, complete... 6 | 633
decreased mean corpuscular vol... 4 | 50
decreased grip strength 2 | 123
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
absent pinna reflex 1 | 21
cardiovascular system phenotyp... 1 | 35
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
hyperactivity 1 | 108
immune system phenotype 1 | 17
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
short tibia 1 | 82
small adrenal glands 1 | 15
small lymph nodes 1 | 1
straub tail 1 | 26
thrombocytosis 1 | 23

Disease

glioblastoma 30 | 5,572
oligodendroglioma 30 | 2,849
medulloblastoma, large-cell 29 | 6,234
ovarian cancer 29 | 8,484
psoriasis 27 | 6,685
atypical teratoid / rhabdoid tumor 25 | 4,369
pilocytic astrocytoma 25 | 3,086
Pick disease 23 | 1,893
primitive neuroectodermal tumor 22 | 3,031
ependymoma 21 | 2,514
lung carcinoma 20 | 2,844
osteosarcoma 20 | 7,933
pediatric high grade glioma 20 | 2,712
subependymal giant cell astrocytoma 18 | 2,287
astrocytic glioma 16 | 2,241
astrocytoma 15 | 1,493
lung cancer 11 | 4,466
medulloblastoma 11 | 1,524
Carcinoma 10 | 2,147
pituitary cancer 10 | 1,972
sonic hedgehog group medulloblastoma 10 | 1,482
Alzheimer's disease 9 | 644
Parkinson's disease 9 | 364
group 3 medulloblastoma 9 | 2,254
malignant mesothelioma 9 | 3,162
Breast cancer 8 | 3,094
Multiple myeloma 8 | 1,327
Schizophrenia 8 | 501
adult high grade glioma 8 | 2,148
posterior fossa group B ependymoma 8 | 1,530
invasive ductal carcinoma 7 | 2,950
Bipolar Disorder 6 | 266
Epilepsy 6 | 346
atypical teratoid/rhabdoid tumor 6 | 1,095
posterior fossa group A ependymoma 6 | 1,511
Osteopetrosis 5 | 40
Tetanus 5 | 66
diabetes mellitus 5 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
non-small cell lung cancer 5 | 2,798
spina bifida 5 | 1,064
Attention deficit hyperactivity disorder 4 | 156
Botulism 4 | 20
Intellectual disability 4 | 573
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
pancreatic cancer 4 | 2,300
tuberculosis 4 | 1,557
Anemia 3 | 252
Cocaine dependence 3 | 24
Cutis laxa 3 | 28
Diarrhea 3 | 155
Gaucher disease type 1 3 | 171
Neurodegenerative disease 3 | 383
Psychotic Disorders 3 | 20
Rheumatoid Arthritis 3 | 1,160
Sensorineural hearing loss 3 | 107
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 780
breast carcinoma 3 | 1,614
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,665
ductal carcinoma in situ 3 | 1,745
glioblastoma multiforme 3 | 347
interstitial cystitis 3 | 2,299
non primary Sjogren syndrome sicca 3 | 840
tuberculosis and treatment for 6 months 3 | 686
Amyotrophic Lateral Sclerosis 2 | 431
Autistic Disorder 2 | 320
Colitis 2 | 46
Coloboma 2 | 51
Dystonia 2 | 77
Early infantile epileptic encephalopathy with suppression bursts 2 | 18
Huntington's disease 2 | 72
Leber congenital amaurosis 2 | 72
Metabolic acidosis 2 | 49
Osteoporosis 2 | 257
Pain agnosia 2 | 99
Parkinson Disease 2 | 102
Peripheral Neuropathy 2 | 303
REM sleep behavior disorder 2 | 16
Velocardiofacial syndrome 2 | 45
Wernicke encephalopathy 2 | 12
adrenocortical carcinoma 2 | 1,427
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 933
esophageal adenocarcinoma 2 | 737
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
hepatocellular carcinoma 2 | 532
interstitial lung disease 2 | 291
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung carcinoma 2 | 413
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
primary pancreatic ductal adenocarcinoma 2 | 1,271

Tissue

Digestive Tract 63 | 18,473
Nervous System 63 | 18,561
Skin and soft tissues 63 | 18,115
Blood and immune system 62 | 17,995
Cardiovascular System 62 | 17,958
Endocrine System 62 | 18,512
Female tissues 62 | 18,647
Liver and Pancreas 62 | 18,136
Urinary Tract 62 | 18,444
Male tissues 61 | 17,969
Respiratory system 60 | 17,484

Target Family

Non-IDG 29 | 11,971
Enzyme 25 | 4,146
Transporter 7 | 473
Ion Channel 2 | 341

KEGG Pathway

Synaptic vesicle cycle 63 | 63
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.36455 23.7 59
V-type proton ATPase subunit e 2 ATP6V0E2 Tdark Enzyme 0.18 0.40 19
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -0.98803 10.3 111
Dynamin-2 DNM2 Tchem Non-IDG -3.22299 1426.1 125
AP-2 complex subunit alpha-2 AP2A2 Tbio Non-IDG -0.63932 4.63 109
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.26936 21.4 27