Development Level

Tbio 26 | 11,445
Tchem 18 | 1,598
Tclin 12 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal behavior 3 | 298
increased circulating alkaline... 3 | 122
abnormal lens morphology 2 | 81
decreased circulating serum al... 2 | 82
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
abnormal male genitalia morpho... 1 | 3
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal tail bud morphology 1 | 8
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased pulmonary respirator... 1 | 5
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating unsatura... 1 | 1
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
small kidney 1 | 16

Disease

Carcinoma 39 | 11,493
psoriasis 29 | 6,694
Prostatic Neoplasms 21 | 495
Cancer 20 | 2,499
medulloblastoma, large-cell 14 | 6,241
ovarian cancer 14 | 8,520
Autosomal recessive predisposition 13 | 1,442
Polycystic ovary syndrome 12 | 360
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
ependymoma 11 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Endometriosis 10 | 540
Hypertension 10 | 396
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung cancer 10 | 4,740
pancreatic cancer 10 | 2,398
Breast cancer 9 | 3,578
Congenital adrenal hyperplasia 9 | 73
Cushing's syndrome 9 | 48
Sickle Cell Anemia 9 | 53
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
malignant mesothelioma 9 | 3,232
osteosarcoma 9 | 7,950
tuberculosis 9 | 2,010
Anemia 8 | 365
Cholestasis 8 | 155
Cryptorchidism 8 | 296
Liver Cirrhosis, Experimental 8 | 769
adrenocortical carcinoma 8 | 1,428
lung adenocarcinoma 8 | 2,716
non-small cell lung cancer 8 | 2,890
Bilirubin metabolic disorder 7 | 41
Hypertensive disease 7 | 292
Obesity 7 | 678
Pericholangitis 7 | 8
Prostate cancer 7 | 175
Schizophrenia 7 | 1,160
adult high grade glioma 7 | 3,801
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
glioblastoma 7 | 5,792
lung carcinoma 7 | 2,843
Alcoholic Intoxication, Chronic 6 | 289
Attention deficit hyperactivity disorder 6 | 278
Breast Neoplasms 6 | 445
Carcinoma, Hepatocellular 6 | 228
Chemical and Drug Induced Liver Injury 6 | 195
Endometrial Neoplasms 6 | 55
Gynecomastia 6 | 64
Hyperaldosteronism 6 | 35
Hyperandrogenism 6 | 34
Liver carcinoma 6 | 240
Mammary Neoplasms 6 | 425
Pick disease 6 | 1,894
Pseudohermaphroditism 6 | 16
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Adenoma 5 | 167
Adrenal hyperplasia 5 | 13
Contact Dermatitis 5 | 81
Delayed bone age 5 | 136
Dermatitis, Contact 5 | 71
Diarrhea 5 | 253
Failure to gain weight 5 | 365
Fatty Liver 5 | 70
Hepatomegaly 5 | 285
Hypoaldosteronism 5 | 12
Hypospadias 5 | 53
Increase in blood pressure 5 | 119
Infertility 5 | 188
Liver disease 5 | 237
Male Pseudohermaphroditism 5 | 19
Mineralocorticoid insufficiency 5 | 12
Osteoporosis 5 | 363
Pediatric failure to thrive 5 | 365
Renal salt wasting 5 | 18
Short stature 5 | 531
pituitary cancer 5 | 1,972
Adrenal cortical adenoma 4 | 19
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Conn's syndrome 4 | 22
Hypercortisolism 4 | 8
Kidney cancer 4 | 2,613
Liver Cirrhosis 4 | 181
Lung Neoplasms 4 | 232
Male infertility 4 | 206
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
esophageal adenocarcinoma 4 | 737
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
nasopharyngeal carcinoma 4 | 1,058

Tissue

Liver and Pancreas 55 | 16,750
Digestive Tract 54 | 17,369
Male tissues 51 | 17,142
Skin and soft tissues 51 | 17,230
Urinary Tract 51 | 16,678
Endocrine System 50 | 18,159
Female tissues 49 | 17,400
Blood and immune system 42 | 16,909
Respiratory system 38 | 16,393
Nervous System 36 | 16,725
Cardiovascular System 26 | 15,192

Target Family

Enzyme 52 | 4,145
Non-IDG 6 | 12,091

KEGG Pathway

Steroid hormone biosynthesis 58 | 58
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
Very-long-chain 3-oxoacyl-CoA reductase HSD17B12 Tbio Enzyme -1.58879 36.7 136
Transmembrane O-methyltransferase LRTOMT Tbio Enzyme -0.92913 14.1 37
Cytochrome P450 11B1, mitochondrial CYP11B1 Tclin Enzyme -2.66308 432.9 136
UDP-glucuronosyltransferase 2A1 UGT2A2 Tdark Enzyme -0.95290 10.2 9
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
UDP-glucuronosyltransferase 2B10 UGT2B10 Tbio Enzyme -1.28053 19.5 91
Estrogen sulfotransferase SULT1E1 Tchem Enzyme -2.97379 932.9 156
UDP-glucuronosyltransferase 2B28 UGT2B28 Tbio Enzyme -0.88835 8.45 45