Development Level

Tbio 108 | 11,651
Tdark 19 | 6,593
Tchem 5 | 1,388

IMPC Phenotype

preweaning lethality, complete... 21 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 4 | 278
decreased vertical activity 3 | 208
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hypoactivity 2 | 132
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal esophagus morphology 1 | 5
abnormal heart morphology 1 | 162
abnormal neural tube morpholog... 1 | 12
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
thrombocytosis 1 | 27

Disease

ovarian cancer 94 | 8,520
Carcinoma 77 | 11,493
osteosarcoma 55 | 7,950
group 3 medulloblastoma 52 | 4,104
lung cancer 44 | 4,740
psoriasis 43 | 6,694
medulloblastoma, large-cell 40 | 6,241
Multiple myeloma 37 | 1,332
glioblastoma 37 | 5,792
oligodendroglioma 27 | 2,850
atypical teratoid / rhabdoid tumor 26 | 5,112
malignant mesothelioma 25 | 3,232
astrocytoma 24 | 1,146
ependymoma 24 | 4,679
acute quadriplegic myopathy 23 | 1,158
diabetes mellitus 22 | 1,728
Kidney cancer 21 | 2,613
Waldenstrons macroglobulinemia 21 | 765
primitive neuroectodermal tumor 19 | 3,035
dermatomyositis 18 | 966
Breast cancer 17 | 3,578
Intellectual disability 17 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
astrocytic glioma 14 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Pick disease 13 | 1,894
lung adenocarcinoma 13 | 2,716
non-small cell lung cancer 13 | 2,890
pancreatic cancer 13 | 2,398
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
adult high grade glioma 12 | 3,801
Conductive hearing loss 11 | 123
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
subependymal giant cell astrocytoma 11 | 2,287
progressive supranuclear palsy 10 | 676
Anteverted nostril 9 | 191
Broad flat nasal bridge 9 | 236
Cancer 9 | 2,499
Nasal bridge wide 9 | 236
acute myeloid leukemia 9 | 783
invasive ductal carcinoma 9 | 2,951
Blind Vision 8 | 111
Blindness, Legal 8 | 110
Cataract 8 | 297
Lens Opacities 8 | 231
Obesity 8 | 678
Retinitis Pigmentosa 8 | 226
breast carcinoma 8 | 1,638
hepatocellular carcinoma 8 | 547
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
nasopharyngeal carcinoma 8 | 1,058
non primary Sjogren syndrome sicca 8 | 891
pituitary cancer 8 | 1,972
Abnormality of retinal pigmentation 7 | 111
Abnormality of the retinal vasculature 7 | 59
Atypical scarring of skin 7 | 62
Congenital anomaly of testis 7 | 52
Congenital hypoplasia of penis 7 | 176
Electroretinogram abnormal 7 | 95
Glaucoma 7 | 239
HIV Infections 7 | 102
Hyperinsulinism 7 | 133
Hypogonadism 7 | 173
Keratoconus 7 | 113
Night blindness, progressive 7 | 51
Nystagmus 7 | 317
Ophthalmoplegia 7 | 106
Optic Atrophy 7 | 242
Photodysphoria 7 | 121
Photophobia 7 | 121
Retinal pigment epithelial abnormality 7 | 111
Rheumatoid arthritis 7 | 1,191
Sensorineural Hearing Loss (disorder) 7 | 284
gastric cancer 7 | 459
juvenile dermatomyositis 7 | 1,187
Cleft Palate 6 | 271
Difficulties with night vision 6 | 87
Epilepsy 6 | 792
Gaucher disease type 1 6 | 180
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Microcephaly 6 | 166
Micrognathism 6 | 275
Night Blindness 6 | 101
Short stature 6 | 531
Uranostaphyloschisis 6 | 167
aldosterone-producing adenoma 6 | 665
atypical teratoid/rhabdoid tumor 6 | 357
pancreatic carcinoma 6 | 562
tuberculosis and treatment for 6 months 6 | 409
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Feeding difficulties 5 | 127
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Small head 5 | 374

Tissue

Endocrine System 132 | 18,159
Blood and immune system 130 | 16,909
Digestive Tract 130 | 17,369
Female tissues 130 | 17,400
Male tissues 130 | 17,142
Respiratory system 130 | 16,393
Skin and soft tissues 130 | 17,230
Urinary Tract 130 | 16,678
Cardiovascular System 129 | 15,192
Liver and Pancreas 129 | 16,750
Nervous System 129 | 16,725

Target Family

Non-IDG 116 | 12,091
Enzyme 13 | 4,145
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

KEGG Pathway

Spliceosome 132 | 132
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U6 snRNA-associated Sm-like protein LSm5 LSM5 Tdark Non-IDG -0.98876 8.80 46
Pre-mRNA-splicing factor SYF2 SYF2 Tbio Non-IDG -1.04825 13.2 124
Probable ATP-dependent RNA helicase DDX23 DDX23 Tbio Enzyme -1.24669 18.6 167
U4/U6 small nuclear ribonucleoprotein Prp31 PRPF31 Tbio Non-IDG -1.84397 72.4 216
Nuclear cap-binding protein subunit 2 NCBP2 Tbio Non-IDG -1.45099 24.2 110
THO complex subunit 4 ALYREF Tbio Non-IDG -2.46163 282.5 0
Pre-mRNA-processing factor 19 PRPF19 Tbio Non-IDG -1.71524 54.2 234
Peptidyl-prolyl cis-trans isomerase E PPIE Tbio Enzyme -1.36546 21.0 185
U4/U6 small nuclear ribonucleoprotein Prp3 PRPF3 Tbio Non-IDG -1.73686 54.3 123
RNA-binding motif protein, X chromosome RBMX Tbio Non-IDG -1.52402 35.8 98